This Pathological Life Podcast

** Thanks for downloading this episode. If you'd like to stay in touch with our continuing story, Season 2 continues at This Medical Life, in which Dr Travis Brown continues his exploration of diseases and our approaches to treatment from history to the modern day. Have a look in your podcast app now for This Medical Life, and hit subscribe so you never miss an episode **

Inherited bleeding disorders before the modern era were a death sentence. Haemophilia, also known as the Royal Disease (specifically Haemophilia B), is an X-linked coagulation disorder that the Heir to the Throne Alexei Romanov inherited in the early 1900’s.

However, in 1926 a Finnish physician by the name of Erik von Willebrand identified a family with a bleeding disorder with an Autosomal Dominant pattern of inheritance.

This was later named von Willebrand Disease (vWD) is now known to be the most common inherited form of bleeding disease worldwide.

This podcast includes an interview with Dr Nicholas Myles regarding our current understanding of Haemophilia A, Haemophilia B, von Willebrand disease, and platelet disorders and this section of the podcast is eligible for 1 RACGP CPD point – self reporting.

See omnystudio.com/listener for privacy information.

** Thanks for downloading this episode. If you'd like to stay in touch with our continuing story, Season 2 continues at This Medical Life, in which Dr Travis Brown continues his exploration of diseases and our approaches to treatment from history to the modern day. Have a look in your podcast app now for This Medical Life, and hit subscribe so you never miss an episode **

The Story of Typhoid Mary

An outbreak of Typhoid occurred 1906 in a wealthy family in Oyster Bay, New York.

Typically a disease of ‘deprived’ people, investigators concluded that the source must have been contaminated water or freshwater clams. However, in 1907, another wealthy family in Manhattan, New York also had an outbreak.

One investigator, George Soper, identified the link: it was the Cook.

Mary Mallon, a.k.a. Typhoid Mary, was found to have worked for 8 different families between 1900-1907; 7 of these families experienced cases of typhoid. Mary was sent into isolation for 2 years and confirmed as a healthy carrier of the bacteria Salmonella typhi but reoffended within 3 months of release.

This is the story of the villain Typhoid Mary vs the tragedy of Mary Mallon.

We thank Fidelma McCorry as the voice behind the reading of Mary's letter.

See omnystudio.com/listener for privacy information.

** Thanks for downloading this episode. If you'd like to stay in touch with our continuing story, Season 2 continues at This Medical Life, in which Dr Travis Brown continues his exploration of diseases and our approaches to treatment from history to the modern day. Have a look in your podcast app now for This Medical Life, and hit subscribe so you never miss an episode **

Smallpox was a devastating disease described as the scourge of the world.

The Variola virus was responsible for countless deaths from antiquity to the twentieth century and left most survivors with lifelong scars.

Using Variolation, a primitive form of vaccination, our ancestors attempted to blunt the full force of Smallpox infections.

However, it wasn’t until the twentieth century and using modern day vaccination techniques that we were able to achieve a monumental milestone and eradicate this disease. 

See omnystudio.com/listener for privacy information.

** Thanks for downloading this episode. If you'd like to stay in touch with our continuing story, Season 2 continues at This Medical Life, in which Dr Travis Brown continues his exploration of diseases and our approaches to treatment from history to the modern day. Have a look in your podcast app now for This Medical Life, and hit subscribe so you never miss an episode **

In the 19th Century there was an increasing numbers of Black Tumours reported in medical literature - described as Melanose in 1806 when Rene Laennec published that the Blackness of these tumours was not related to black carbon deposits found in the lungs of patients upon autopsy.

By mid 20th Century, a more evidence based approach was taken.

Today, through molecular biology advances, we know genetic mutations are important in the genesis of tumours such as melanoma.

This podcast includes an interview with Dr Craig James MBBS (Hons), FRCPA, AACD and this section of the podcast conducted by Dr Craig James is eligible for 1 RACGP CPD point – self reporting.

Episode notes, references and learning objectives, available at

https://www.clinpath.com.au/about-us/podcast-this-pathological-life/2020/07/episode-three-the-black-tumour

This Pathological Life is produced by Clinpath Pathology in South Australia.

Dr Craig James

MBBS (Hons), FRCPA, AACD

Specialties Cytopathology, Dermatopathology, and Histopathology

Bio:

https://www.clinpath.com.au/about-us/clinpath-leadership/our-pathologists/dr-craig-james/

See omnystudio.com/listener for privacy information.

** Thanks for downloading this episode. If you'd like to stay in touch with our continuing story, Season 2 continues at This Medical Life, in which Dr Travis Brown continues his exploration of diseases and our approaches to treatment from history to the modern day. Have a look in your podcast app now for This Medical Life, and hit subscribe so you never miss an episode **

Through the prism of COVID-19 and epidemiology, we examine different epidemics and pandemics throughout history. In the last twenty years, there have been three outbreaks of Coronavirus (MERS, SARS, and COVID-19) but only COVID-19 reached pandemic status. The question must be asked as to why?

Episode notes, references and learning objectives, available at

/podcast-this-pathological-life/2020/07/episode-two-anatomy-of-a-pandemic

This Pathological Life is produced by Clinpath Pathology in South Australia.

See omnystudio.com/listener for privacy information.

** Thanks for downloading this episode. If you'd like to stay in touch with our continuing story, Season 2 continues at This Medical Life, in which Dr Travis Brown continues his exploration of diseases and our approaches to treatment from history to the modern day. Have a look in your podcast app now for This Medical Life, and hit subscribe so you never miss an episode **

Pathology is by definition: the study of disease.
Pathology is about understanding.

This episode uses the story of Mary Papanicolaou and her husband George who discovered the pap smear.

Dr Travis Brown says, “What I’m hoping is that this podcast explores the evolution of Pathology from historical perspectives to the current day understanding. This may be about a disease or an event or a person. So much can be learnt and there are some fascinating stories like the example of Mary Papanicolaou. Mary Papanicolaou’s contribution has led to hundreds of thousands of lives being saved and unfortunately, she is little more than a sentence or two in historical records.”

This episode also covers:

1. Diabetes (as a discussion example)
2. How does someone become a pathologist?
3. Pathologists: medical school / junior doctor / registrar
4. How many different kinds of pathologists are there?

Episode notes, references and learning objectives, available at

clinpath.com.au/about-us/podcast-series/2020/07/episode-one-this-pathological-life

This Pathological Life is produced by Clinpath Pathology in South Australia.

See omnystudio.com/listener for privacy information.