Toxicologic Pathology & Veterinary Science

TPX: Unexpected Thrombocytopenia and Anemia in Cynomolgus Monkeys Induced by a Therapeutic Human Monoclonal Antibody


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A discussion with Drs. Nancy Everds, Nianyu Li and Katherine Sprugel from Amgen in Seattle, Washington about the article “Unexpected thrombocytopenia and anemia in cynomolgus monkeys induced by a therapeutic human monoclonal antibody”.  This manuscript won the journal’s best paper award in 2013 and describes a study that is a cautionary tale for those investigating/testing monoclonal antibodies.

 

Click here to read the full article.  

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Toxicologic Pathology & Veterinary ScienceBy Sage Publications

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