The recent Quartet Study evaluated initial hypertension pharmacotherapy - specifically, the role of using four antihypertensives at a low dose compared to usual step therapy. Does a small dose of multiple medications work better than one high dose medication?

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References and resources: Chow CK, Atkins ER, Hillis GS, et al. QUARTET Investigators. Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomized, double-blind, active-controlled trial. Lancet. 2021 Sep 18;398(10305):1043-1052. doi: 10.1016/S0140-6736(21)01922-X. Epub 2021 Aug 29. PMID: 34469767.

Continuing Education Information:
Learning Objectives:
1. Describe the medications used in the QUARTET study
2. Apply the results of the QUARTET study to a patient with hypertension

0.05 CEU | 0.5 Hrs
ACPE UAN: 0107-0000-21-356-H01-P
Initial release date: 10/25/21
Expiration date: 10/25/22
Complete CPE and CME details can be found here

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