Program notes:

0:34 Chronotrope type and timing of exercise

1:36 Sedentary adults and morning or evening type

2:36 Acting as your own control

3:10 Stenting for post thrombotic syndrome

4:10 Severity lower with endovascular therapy

5:10 Patent in 2/3 at six months

6:10 Very diverse patient populations

6:28 Estimating kidney function

7:28 Currently underestimate compromise

8:27 Deprescribing proton pump inhibitors

9:27 Three different interventions

10:27 Almost 15% achieved outcome in both patient and physician

12:08 End

Program notes:

0:36 How low should cholesterol be targeted in secondary prevention?

1:40 33% reduction with target to 55

2:36 Able to do it with statin and other drugs

3:03 Deprescribing levothyroxine

4:06 Were able to discontinue in many 

5:05 Thyroid not as responsive with aging

6:05 Barriers to deprescribing?

6:31 Treatment of HTN in low-income patients

7:31 75% unemployed

8:31 Patient participates

9:06 Manufacturer coupon use

10:10 Annual patient use of coupons

11:18 Used to drive people to use drugs that are expensive

12:33 End

Program notes:

0:38 Migrating biopharma industry

1:36 Early stage development

2:36 Need to replicate studies

3:23 Treatment for fatigue from long Covid

4:25 Fluvoxamine or metformin

5:25 Only fluvoxamine helped

6:25 Only for fatigue

6:35 How treatments for hepatitis C have been used

7:36 Number of people receiving treatment declining

8:36 Need a better system

9:16 Dulaglutide or tirzepatide and patient reported outcomes

10:17 Quality of life metrics

11:43 End

Program notes:

0:36 High versus standard-dose flu vaccines in older people

1:36 Cardiovascular outcomes

2:26 Also in those with previous CVD

3:10 Cooking and dementia risk

4:10 Cooking frequency and skills assessment

5:10 Tasks relative to preparing a meal at home

6:10 Encourage home cooking

6:30 Asymptomatic aortic stenosis treatment

7:30 Replace valve before symptoms

8:30 Trained cardiologist can grade

9:10 Pediatric sepsis in U.S. hospitals

10:17 About 51,000 cases

11:17 Adult criteria may not be in EHR

12:29 End

Program notes:

0:35 New cholesterol lowering guidelines

1:35 Risk scores new

2:35 Mainstay is behavioral change

3:35 For those with a longer view

4:00 AI based glaucoma screening in primary care settings

5:00 Either AI or pressure

6:00 Fundus photograph and intraocular pressure

7:00 Sensitivity and specificity

7:50 Diet and brain structure

8:50 Brain imaging over ten or fifteen years

9:50 Diet that's been advocated for a long time

10:55 Surveying wastewater for colorectal cancer markers

11:55 CDH1 marker measurement

12:55 Shows promise for intervention

13:57 End

Program notes:

0:44 Adolescents and sleep duration

1:44 Very short sleep duration

2:44 Increased among all subgroups

3:45 Structural factors more important

4:45 Moving school start later

5:02 GLP1 agonists and various patient characteristics

6:02 Greater weight loss in women

7:06 A blood test to predict onset of symptomatic Alzheimer's

8:06 Median error of 3-4 years

9:06 Window of 11.4 years for an 80 year old

10:05 Screening for colorectal cancer 

11:05 Colonoscopy and FIT diagnosed early

12:33 End

Program notes:

0:37 HIV treatment monthly injections

1:37 Long acting and effective

2:37 Some didn't come for monthly injections

3:16 COVID-19 vaccination and preeclampsia rate

4:16 In two successive cohorts during pandemic

5:16 Pre-existing morbidity 58% reduction

6:15 COVID-19 cytokine storm?

6:45 Monkeypox treatment

7:45 Randomized to placebo or smallpox drug

8:50 Menstrual blood to test for HPV

9:50 Minipad essentially the same as clinician collection

10:45 Can make it cost effective?

11:49 End

Program notes:

0:37 Hormone therapy and mortality

1:37 Those who used versus those unexposed

2:35 Different types of HT

3:32 Adolescent cannabis use and mental illness

4:32 Screened in physician office

5:32 Action at societal and government levels

6:00 Access to dialysis facilities and SES

7:01 2.3 % of advantaged communities lacked access

8:01 For profit centers consolidate

9:01 Roughly half of nephrology spots unfilled

9:33 ACOs and Medicare savings

10:33 Initial study showed net savings

11:16 Fragile savings estimate

12:09 End 

Program notes:

0:35 Diabetes and food prescriptions

1:35 Got a food card to purchase nutritious foods

2:32 More than half didn't use it or used it less than 60%

3:00 Adequacy of a planetary health diet

4:00 Micronutrient intake and biomarkers

5:00 Doesn't seem to compromise long-term health

6:12 Statin recommendations and patient preferences

7:00 Benefit/risk analysis for patients

8:00 Patient's decisions are multifactorial

9:00 Resistance to daily medication

9:30 Findings on shoulder MRI

10:35 Rotator cuff abnormalities in almost 99%

11:35 Almost ubiquitous regardless of symptoms

12:25 Physical therapy best strategy

13:23 End

Program notes:

0:38 Removal of fallopian tubes to prevent ovarian ca

1:43 129 studies included

2:43 Women who no longer desire pregnancy

3:40 Technically feasible

4:30 New oral PCSK9 inhibitor

5:35 Think it's a slam dunk

6:08 EHR helping deprescribing in older adults

7:08 Two sequential EHR interventions

8:08 40% more likely in one group

9:08 Something in email less effective

9:50 Benefits of knee braces for OA

10:50 Brace specific to area of OA

12:00 If it results in a placebo effect

13:00 End