TT HealthWatch

Program notes:

0:33 Statins for older people without CVD

1:34 Followed for six years

2:34 Aged to 70 without CVD

3:00 Improving primary care for folks with chronic conditions

4:00 70,000 respondents

5:00 Long term relationship with a primary care provider

6:00 Continuity and coordination can be delivered at scale

7:09 Treating advanced breast cancer

8:10 Mutation in estrogen receptor

9:12 Targeting specific mutations

10:00 A new target for managing asthma and COPD

11:00 Healthy volunteers and patients with asthma

12:00 Typically treated with immunosuppression

13:05 End

Program notes:

0:40 Structured exercise after cancer

1:40 Moderate evidence

2:40 Improves overall survival

3:41 Improves drug penetration

4:00 Colonoscopy intervals after polyp removal

5:00 Five-year cumulative incidence same as three years

6:03 Covid vaccination and immune checkpoint therapy

7:03 Mortality as primary outcome

8:04 Multiple benefits of vaccination

9:03 Other vaccines of benefit?

9:50 Does sodium bicarbonate help in critical illness and shock

10:50 Metabolic acidosis tx

11:50 Largely futile

12:37 End

Program notes:

0:37 New stroke therapy

1:37 Use of IV for 10 days after stroke

2:37 Present late after a stroke

3:39 Long term outcomes of top-down therapy in Crohn's

4:40 Outcomes up to five years

5:40 Early TNF use from diagnosis improves outcomes

6:42 No real downside

7:38 How much oxygen for 32–35-week neonates?

8:34 Ongoing respiratory support needed?

9:34 Not hypoxic to begin with

9:50 Feeding eggs and peanuts during pregnancy

10:50 Did not impact risk for infant allergy

11:50 One third dropped out

13:03 End

Program notes:

0:33 Vaccines for RSV, flu, and Covid

1:35 Studies available right now

2:33 Reduction of hospital encounters for infants

3:33 Maternal vaccination for RSV

4:34 Gene silencing therapy for cardiomyopathy

5:35 Decreased primary outcome about 20%

6:35 Should we be screening?

7:06 A new protein to pinpoint preeclampsia

8:05 Low levels in first trimester

9:08 Anchors embryo to uterus

10:05 A new therapy for COPD exacerbations

11:05 Phase three trial of monoclonal

12:34 End

Program notes:

0:44 EKG monitoring and syncope

1:45 No difference when monitored

2:45 Why not try monitoring?

3:13 Catheter directed thrombolysis in PE

4:14 Composite of death from any cause

5:14 Assessment for intermediate or high risk

6:16 Treatment not onerous

6:45 Afib ablation versus sham

7:45 Did not improve quality of life

8:45 Preprocedure assessment of psychological state?

9:13 Digital intervention to protect cognitive health

10:13 Verbal reasoning at 12 months

11:13 As long as internet is available

12:15 What happens at five-year follow-up

13:09 End

Program notes:

0:35 Devices to do CPR versus manual

1:37 About 60% of U.S. population

2:32 8-9% survive with favorable neurologic status

3:15 Ventilated patients and reduction of mucous secretions

4:15 Duration of ventilation unchanged

5:15 Regulate or expectorate

5:40 Boarding ED patients

6:45 Adults admitted to general medicine service

7:45 More common in older patients

8:45 Can initiate inpatient management

9:24 Cold stored platelets versus room temp

10:24 Hemostatic efficiency score

11:30 Historically used in cancer patients

12:45 End

Program notes:

0:38 Polymyalgia rheumatica treatment

1:35 Antibody targets interleukin 17a

2:35 Remission started at 12 weeks and was durable to 52

3:11 Cannabis and hyperemesis syndrome

4:11 Cannabis-related ED visits

5:11 Prior to the new coding didn't link

6:05 Gene inhibition of PCSK-9

7:05 Encased in a nanoparticle

8:11 Three vascular risk factors and dementia

9:11 Stratified by age, sex, apoE status

10:13 13 additional dementia-free years

11:58 End

Program notes:

0:44 Novel agent for acute pain

1:44 Post-abdominal surgery and placebo, low and high dose

2:46 Compared to placebo and opioids

3:19 Metabolic associated steatotic liver disease

4:19 Imaging with two techniques and plasma markers

5:19 Imaging and composite scores for staging

6:21 Identifying appropriate candidates for clinical trials

7:00 Alcohol consumption during pregnancy

8:00 Employed, tobacco use, and mental stress predicts

9:01 Never tested medicines for AUD in pregnant women

9:24 Early detection of Alzheimer's disease with circular RNA

10:24 Can it identify those with the disease as well as those at risk

11:24 Almost 95% AUC

12:20 Use with tau, it was even better

13:05 End