Program notes:

1:25 mRNA flu vaccine

2:25 Phase three trial

3:25 Preventing infection with a respiratory virus

4:25 Prophylaxis with NSAID?

4:45 Umbrella review of acetaminophen in pregnancy, ASD and ADHD

5:42 Confidence was low to critically low

6:45 Other factors such as environmental exposures

7:22 Increasing potassium to prevent heart arrythmias

8:33 Increase with supplements or dietary advice

9:18 Canceling funding for clinical trials

10:18 In the process of receiving interventions

11:18 Can't not analyze 

12:15 End

Program notes:

0:50 Fish oil supplements and hemodialysis

1:50 1200 individuals to fish oil or not

2:50 Needs another study

3:11 PCSK9 inhibitor in people without MI or stroke

4:13 3- or 4-point MACE

5:11 Getting LDL down helps

6:11 Addition of more than one oral agent

6:50 Right therapy for afib and a stent

7:50 Noninferiority trial

8:50 After 12 months single agent works

9:27 Anticoagulation after afib tx

10:30 Low primary safety outcomes

11:25 96% won't have a stroke

12:16 End

Program notes:

0:37 An oral med for obesity

1:37 Five to 10% stopped medication

2:35 Need head-to-head trials with injectable

3:00 Stem cell infusion after MI and heart failure

4:01 Reduced heart failure in recipients

5:01 Twice as many in the control arm

6:01 Moving past BMI in predicting atherosclerosis

7:01 Especially in overweight but not obese

8:01 Almost 3000 participants in Brazil

8:25 Blood samples precede MS

9:04 Seen seven years beforehand

10:02 Twin studies and relatives

11:03 Way to intervene earlier

11:15 Applaud OpenAI

13:00 End

Program notes:

0:45 Steps, more and longer?

1:45 8,000 steps or less

2:45 Nothing on intensity

3:30 Mediterranean diet for IBS

4:30 Reduction in IBS symptom severity scale

5:30 Easy to accommodate with high compliance

6:30 Exercise for knee osteoarthritis

7:30 All types of exercise examined

8:30 Initiated exercise to try to address

9:00 AI intervention in prediabetes

10:00 Based on diabetes prevention program

11:00 AI and human led essentially the same

12:00 99% of eligible group don't have access

13:09 End

Program notes:

0:40 Nicotine reduction for various subgroups

1:40 Native American and Alaskan populations benefit most

2:42 Black, rural populations 10 million lives saved

3:40 19-39 million life years saved

4:00 Food insecurity and blood pressure

5:00 Food vouchers most successful

6:00 May be more involved and motivated

6:35 PFAS and infant brain architecture

7:35 Children assessed with MRI

8:30 Didn't correct for various factors

9:31 Other types of plasticized chemicals

9:50 Afib after cardiac surgery

10:50 Only found with implantable monitor

11:50 Very short duration of afib

12:51 End

Program notes:

0:40 New drug for SLE

1:41 Monitored for a year

2:43 Only one pathway limited

3:00 AI and health care

4:00 How to assure compliance?

5:00 Policy changes needed

6:01 Pessimistic about oversight

6:50 Genetic treatment for ADA deficiency

7:50 Using a viral vector

8:50 A curative treatment

9:30 Social media and cognitive performance in adolescents

10:30 Low and high increasing social media use

11:30 Good enough evidence

12:31 End

Program notes:

0:40 Aldosterone as a risk factor for heart disease

1:40 Spectrum of renin-aldosterone levels

2:40 As many as 25-30% may have

3:11 All pharmacologic interventions for obesity tx

4:14 All effective compared with placebo

5:12 Meta-analysis 

6:13 Very little data in overweight or massively obese

6:35 Where do U.S. antibiotics come from?

7:35 India leading country for finished product

8:20 Environmental impact of inhalers

9:20 Annual emissions increased by 24%

10:23 Decreased by 43%

11:23 Three forms of inhaler

12:40 End

Program notes:

1:21 Bronchiectasis treatment

2:22 Twenty sites in UK

3:20 Medical imaging and cancer risk in kids

4:20 3000 hematologic cancers

5:20 Consider other types of imaging

6:23 Head CT increases risk by 35%

7:24 Treating pulmonary arterial hypertension

8:24 Improved mortality in another trial

9:25 Antibody prevention of RSV in healthy infants

10:25 Healthy preterm and full term infants

11:25 Argues for use of this antibody globally

12:25 Antibodies against antibody didn't compromise

13:08 End

Program notes:

0:40 Private equity takeover of hospitals

1:40 Reduced salaries or staffing

2:40 Patients likely to cost system

3:30 Use of anti thymocyte globulin to slow down T1D in youth

4:30 Diagnosed within 9 weeks prior

5:30 Serum sickness in 82% of highest dose group

6:30 Incidence increasing by 2% per year over 20 years

7:00 Aspirin in CRC

8:00 1100 patients with mutation

9:00 Can this mutation be acquired?

9:15 Alcohol and dementia

10:15 Confounding factors relative to alcohol use

11:15 Is there a safe level of consumption?

12:40 End

Program notes:

0:45 Intimate partner violence and CVD

1:45 12% reported stalking

2:46 Screening in primary care

3:47 Fifty to 200% increased risk

4:00 Number of psychiatric disorders and dementia risk

5:00 Important to be aware when mental health disorders exist

6:03 Anxiety and depression associated

6:33 Lipoprotein(a) and widespread vascular disease

7:31 High risk of extracoronary vascular disease

8:32 Also associated with complications

9:32 Unknown why some areas affected

10:00 Second cancers after early invasive breast cancer

11:00 Contralateral breast cancer greater in younger women

12:00 Not excessive risk

13:31 End