Fish oil supplements are a huge industry. Americans spend more than $1 billion a year on them, hoping to support brain health by taking in the omega-3 fatty acids they contain.
A new study may provide a dose of reality, however. A two-year clinical trial conducted by University of Southern California researchers found that while fish oil supplements do deliver omega-3s to the brain, there is no meaningful benefit for memory, cognition or Alzheimer’s-related changes.
On its face, taking fish oil supplements is not illogical. Omega-3s, healthy fats found in some fish, help build the connections between brain cells key to our ability to think and remember.
More than 350 people between the ages of 55 and 80 who rarely ate fish were enrolled in the study. All were at elevated risk for Alzheimer’s disease. They were placed in two groups. One group was given a daily, high-dose fish oil supplement; the other group got a placebo.
Each supplement contained 2,000 milligrams of docosahexaenoic [duh-kow-suh-hek-suh-know-ick] acid, or DHA, an omega-3 important in brain function. For the brain, DHA is like premium oil is to an engine.
By measuring DHA levels in participants’ cerebrospinal fluid, they could see it did indeed reach the brain.
Even so, that did not equate to measurable cognitive benefits. Participants went through memory tests at the start of the study and two years later. Those who took DHA supplements performed no better than the placebo group.
For now, the researchers say those who hope to safeguard brain health should focus on eating nutritious food and staying fit. And eating salmon, mackerel, sardines and anchovies surely can’t hurt.