Meredith Perry, CEO and co-founder of Elemind, has built something genuinely revolutionary: a wearable headband that uses real-time EEG and sound pulses to interrupt the brainwaves keeping you awake. Clinically proven. Published in Nature. The median user falls asleep in 11 minutes.

The problem? Science doesn't sell. People don't believe you.

In this episode, Meredith breaks down how she solved the trust gap that kills most innovative products. She walks Jason through the actual technology (and demos it on him live during the podcast), then unpacks the guerrilla marketing strategy that put Elemind on the map: "Sleep With Our CEO," where she goes around New York knocking out strangers in Times Square, on the Staten Island Ferry, outside Giants games, anywhere people don't expect to fall asleep.

If you're a founder with a complicated product and a skeptical market, this one is for you.

Timestamps:

00:00 Cold open

04:10 The real innovation gap: getting people to believe you

06:09 What Elemind actually is and how it works

07:18 Putting 500 people to sleep at CES

08:58 The neuroscience, explained simply

11:02 Live demo: Jason tries the headband on the podcast

17:10 Why leading with science doesn't sell

19:24 The "Sleep With Our CEO" guerrilla campaign

22:06 Why founders have to become the face of accountability

25:30 How humor became the strategy

28:32 Amplifying the truth: if it works in Times Square, it works anywhere

30:09 The language masterclass: noise cancellation for the brain, app store for the brain

34:04 Balancing humor with serious science

36:02 Customer feedback that changed the strategy

37:14 Why comfort beat futuristic design

40:26 The one question every consumer asks

41:03 Advice for founders with revolutionary products nobody understands

43:04 Where to get Elemind

Sans Thakur, CEO and Chairman of Tower Capital Group, joins Jason Feifer to explain why the longevity industry is missing the point. The real frontier is generational health: the science of how your DNA, environment, and choices create cascades that shape your descendants' health for up to 16 generations.

Sans is one of the named pioneers of generational health. She spent decades helping launch 40+ medicines that reached 6 million patients before becoming an investor. In this conversation, she breaks down what's actually possible right now: dementia prevention infusions that cut risk by 50%, bio-AI that can grow a beating heart from a drop of your blood, and why the food you eat is interacting with your cells in ways science is only beginning to understand.

If you've been skeptical of the longevity hype but curious about what real science can do, this episode is for you.

Disclaimer: The science descriptions are ultra simplified for general audience consumption.

Timestamps:

00:00 Cold open

01:25 Why longevity has become "fluffy" and what it used to mean

02:30 What Tower Capital Group actually does

09:12 Defining generational health and the 16-generation cascade

13:53 From Human Genome Project to today's bio-AI breakthroughs

18:00 The dementia prevention infusion that cuts risk by 50%

21:30 Genetic cascades explained: how your choices imprint on your DNA

24:35 Growing a beating heart from a drop of blood

28:30 Bioethics and why this technology isn't available to everyone yet

29:32 Your mother's mitochondria and why maternal health is underfunded

32:00 Why longevity influencers get it wrong

36:38 Food as medicine and the data gap between groceries and clinics

40:12 How much do we actually know about food and the body?

46:13 How to get involved with Tower Capital Group and Uncharted Pitches

52:48 The "spackle" and why small wins matter too

Sans Thakur, CEO and Chairman of Tower Capital Group, joins Jason Feifer to explain why the longevity industry is missing the point. The real frontier is generational health: the science of how your DNA, environment, and choices create cascades that shape your descendants' health for up to 16 generations.

Sans is one of the named pioneers of generational health. She spent decades helping launch 40+ medicines that reached 6 million patients before becoming an investor. In this conversation, she breaks down what's actually possible right now: dementia prevention infusions that cut risk by 50%, bio-AI that can grow a beating heart from a drop of your blood, and why the food you eat is interacting with your cells in ways science is only beginning to understand.

If you've been skeptical of the longevity hype but curious about what real science can do, this episode is for you.

Timestamps:

00:00 Cold open

01:25 Why longevity has become "fluffy" and what it used to mean

02:30 What Tower Capital Group actually does

09:12 Defining generational health and the 16-generation cascade

13:53 From Human Genome Project to today's bio-AI breakthroughs

18:00 The dementia prevention infusion that cuts risk by 50%

21:30 Genetic cascades explained: how your choices imprint on your DNA

24:35 Growing a beating heart from a drop of blood

28:30 Bioethics and why this technology isn't available to everyone yet

29:32 Your mother's mitochondria and why maternal health is underfunded

32:00 Why longevity influencers get it wrong

36:38 Food as medicine and the data gap between groceries and clinics

40:12 How much do we actually know about food and the body?

46:13 How to get involved with Tower Capital Group and Uncharted Pitches

52:48 The "spackle" and why small wins matter too

In the early days of AI products, buyers were willing to experiment and take risks. Now they expect clear ROI. That’s changing the way that AI products are taken to market.

Rachel ten Brink, GP and co-founder of Red Bike Capital, breaks down what’s actually working now: founder-led sales, distribution moats, customer adoption, enterprise champions, strategic partnerships, and why the companies that win won’t necessarily have the best models — they’ll have the best go-to-market strategy.

You don’t win on product alone. You win by recognizing the white space that’s hidden in plain sight

In this episode, Jason talks with beverage entrepreneur Michelle Ivey — who built Illegal Mezcal and sold it to Bacardi, helped Megan Thee Stallion launch her tequila, and is now building multiple beverage brands — about what it actually takes to stand out when every shelf is full.

During big technological shifts, leaders face a difficult question: How do you project calm and vision, while everything around you changes?

Raynmaker CEO Joe Gagnon has led six companies, and has an answer: You must move as fast as the change itself. He explains how to create confidence in uncertain times, where AI actually helps (not hurts), and why the fundamentals of business matter more than ever.

How do founders stay calm, think clearly, and find answers faster when everything goes wrong?In this episode, host Jason Feifer talks with Gambit Robotics cofounder and former U.S. chess player Nicole Maffeo about the real mechanics of problem solving. They break down how great operators handle ambiguity, why patience is now a competitive advantage, how to “chunk” complex problems into solvable parts, and why losing well may be one of the most valuable entrepreneurial skills.

If you’re thinking about a pivot, a new venture, or a move into unfamiliar territory, this conversation will give you a smarter way to think about starting from scratch.

In this episode, Jason Feifer talks with Michael Louis, cofounder and CEO of the AI company Cerebrium, about what it takes to win in spaces you’ve never worked in before. Michael has built companies across blockchain, e-commerce, and AI, and he explains how he approaches every new market: by invalidating ideas fast, solving the next problem instead of obsessing over the long-term plan, building highly autonomous teams, and using relationships to accelerate learning and growth.

Burnout is the greatest danger to any ambitious founder. But with the right strategies, you can drive hard, grow fast, and preserve your sanity. Dr. Taryn Marie Stejskal explains how. She’s the founder of the Resilience Leadership Institute, was previously head of executive leadership development & talent strategy at Nike, and a recognized expert on resilience and burnout.

Tim Draper graciously joined us while traveling, so we appreciate your patience with any audio variances during the conversation.

In this episode of Uncharted, legendary venture capitalist Tim Draper joins for a wide-ranging conversation that’s part masterclass, part manifesto. From backing 20+ unicorns and buying Bitcoin when no one else would, to founding Draper University and creating a global pitch show, Draper unpacks his philosophy, his aversion to bureaucracy, and why trust and freedom are the bedrock of innovation. He shares war stories from early DFJ days, reflects on the rise and fall of China’s entrepreneurial boom, and dishes out advice on where the smart money should go next.

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