University of California Video Podcasts (Video)

Manish Mehta is the VP of Marketing and Operations for the Optical Systems Division at Broadcom. Manish leads go-to- market and operational activity for the division responsible for developing and manufacturing devices and systems used in optical communications. Prior to joining Broadcom, Manish was EVP and Product Line Management of Source Photonics where he led the company's entry into the datacenter market. Manish holds a Ph.D. in Electrical Engineering from The University of California, Santa Barbara, and B.S. in Electrical Engineering from The University of Texas. Series: "Institute for Energy Efficiency" [Science] [Show ID: 38465]

What role do genetics, diet, exercise and cholesterol play in preventing and treating diseases of the heart? Learn about advances in the prevention and treatment of heart disease, including an overview of abnormal rhythms such as atrial fibrillation and diet with Dr. Gregory Marcus. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 38481]

Treatment options for problematic behaviors associated with severe autism are limited. Can cannabidiol (CBD) be an effective therapy? Doris Trauner, M.D., discusses recent studies looking at the use of CBD and how it works in the brain. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Show ID: 38393]

What role do genetics, diet, exercise and cholesterol play in preventing and treating diseases of the heart? Learn about advances in the prevention and treatment of heart disease, and what you and your doctor can do to minimize risk with Dr. Carlin Long. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 38482]

New technologies, shifting demographics and changing societal expectations point to the need for people from all walks of life to be part of fact-based discussions regarding the checks and balances in place when it comes to human research. Anthony Magit, M.D., M.P.H., shares the importance of institutional review boards (IRBs), oversight, and consent when doing research with human subjects. He is joined by Pratheesh Sathyan, Ph.D., and George Hightower, M.D., for a wide-ranging discussion of clinical trials, HIPAA, research design, consumer genetic testing and more. Series: "Exploring Ethics" [Health and Medicine] [Humanities] [Show ID: 38421]

Moderator Mireille Miller-Young joined Diversity in Cannes founder Yolonda Brinkley and filmmaker Wendy Eley Jackson to discuss this important initiative and to celebrate the achievements of global Black women in film. Collectively, they outlined the background and impact of the initiative and strategies for Black women and their allies to create global change. They also reflected on the serious representation gaps in the international film industry and their own experiences breaking barriers. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 38549]

Ram Huggahalli is a Principal Hardware Engineer in Microsoft's Azure Hardware Systems and Infrastructure group. His focus areas are hyper-scalar systems architecture, SoC/platform-level interconnects and accelerator architecture strategies for the next 2-4 years. Prior to Microsoft, Ram has been with Intel Corporation contributing to memory and I/O subsystem directions in various Xeon processors and platforms, large scale HPC interconnect product roadmaps and system level simulation methodologies. Ram has MS degrees in Electrical Engineering and Engineering Management from Missouri University of Science and Technology. Series: "Institute for Energy Efficiency" [Science] [Show ID: 38464]

Alysson Muotri discusses modeling Pitt-Hopkins syndrome (PTHS) using stem cells and brain organoids. He shares how rescuing TCF4 expression with CRISPR-mediated epigenetic induction of AAV vector delivery provides a gateway for targeted therapeutics for PTHS and related conditions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38516]

Rob Stone is a member of the infrastructure team at Meta, focusing on next generation optics and networking. Prior to Facebook, Rob was a distinguished engineer at Broadcom within the switch architecture team. He is active in industry communities including IEEE and other MSAs. Rob holds a D.Phil. in Physics from The University of Oxford. Series: "Institute for Energy Efficiency" [Science] [Show ID: 38463]

The human brain has a larger mass with respect to body weight, increased cortical neurons with respect to size, an expanded proliferative zone, and unique connectivity patterns. Human-specific neurodevelopment is not only marked by physical differences, but also by temporal changes. Human neurons, during both prenatal neurodevelopment and adult neurogenesis, exhibit an exceptionally delayed time course, a characteristic termed neoteny. Signatures of human-specific neoteny have been observed and reproduced across different systems including induced pluripotent stem cell (iPSC) and brain organoids models. We compared neurogenesis across stem cells from five primate species - rhesus, gorilla, bonobo, chimpanzee, human - and assessed the differences in transcriptional dynamics. We identified a pioneer transcription factor, GATA3, that exhibited elevated neuronal expression only in humans. This finding provides evidence for the divergence of gene regulation as a contributor to human neoteny. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38301]