It will be the shot heard ‘round the world, once it comes. But exactly when can we expect a COVID vaccine? We discuss timelines, how it would work, who’s involved, and the role of human challenge trials. 
Also, although he doesn’t consider himself brave, we do. Meet a Seattle volunteer enrolled in the first coronavirus vaccine trial. And, while we mount an elaborate defense against a formidable foe, scientists ask a surprising question: is a virus even alive?
Guests:


Nigel Brown – Emeritus Professor of Molecular Microbiology at the University of Edinburgh


Ian Haydon – Public information specialist at the University of Washington, Seattle


Bonnie Maldonado – Professor of Pediatrics and Infectious Diseases at the Stanford University School of Medicine


Paul Offit – Head of the Vaccine Education Center, and chief of the Division of Infectious Diseases, at Children’s Hospital of Philadelphia


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Vaccine, When?

The surprising connections in science and technology that give you the Big Picture. Astronomer Seth Shostak and science journalist Molly Bentley are joined each week by leading researchers, techies, and journalists to provide a smart and humorous take on science. Our regular "Skeptic Check" episodes cast a critical eye on pseudoscience.

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It was a radical idea a century ago, when Einstein said space and time can be bent, and gravity was really geometry. We hear how his theories inspire young minds even today.
At small scales, different rules apply: quantum mechanics and the Standard Model for particles. New experiments suggest that muons – cousins of the electron – may be telling us that the Standard Model is wrong. Also, where the physics of both the large and small apply, and why black holes have no hair.
Guests:
Hakeem Oluseyi – Astrophysicist, affiliated professor at George Mason University, and author of “A Quantum Life: My Unlikely Journey from the Street to the Stars”
Janna Levin – Professor of physics and astronomy, Barnard College at Columbia University
Mark Lancaster – Professor of particle physics, University of Manchester
*Originally aired August 16, 2021
Featuring music by Dewey Dellay and Jun Miyake
You can get early access to ad-free versions of every episode by joining us on Patreon. Thanks for your support!
Big Picture Science is part of the Airwave Media podcast network. Please contact advertising@airwavemedia.com to inquire about advertising on Big Picture Science.
 
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Phreaky Physics*

Above the Arctic Circle, much of the land is underlaid by permafrost. But climate change is causing it to thaw. This is not good news for the planet. 
As the carbon rich ground warms, microbes start to feast… releasing greenhouse gases that will warm the Earth even more.
Another possible downside was envisioned by a science-fiction author. Could ancient pathogens–released from the permafrost’s icy grip–cause new pandemics? We investigate what happens when the far north defrosts.
Guests:
Jacquelyn Gill – Associate professor of paleoecology at the University of Maine.
Jim Shepard – Novelist and short story writer, and teacher of English at Williams College, and author of “Phase Six.”
Scott Saleska – Global change ecologist, professor of Ecology and Evolutionary Biology at the University of Arizona, and co-founder of IsoGenie.
Originally aired September 6, 2021
Featuring music by Dewey Dellay and Jun Miyake
You can get early access to ad-free versions of every episode by joining us on Patreon. Thanks for your support!
Big Picture Science is part of the Airwave Media podcast network. Please contact advertising@airwavemedia.com to inquire about advertising on Big Picture Science.

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De-Permafrosting*

Birds have it going on. Many of these winged dinosaurs delight us with their song and brilliant plumage. Migratory birds travel thousands of miles in a display of endurance that would make an Olympic athlete gasp.
We inquire about these daunting migrations and how birds can fly for days without rest. And what can we do to save disappearing species? Will digital tracking technology help? Plus, how 19th century bird-lovers, appalled by feathered hats, started the modern conservation movement.
Guests:
Scott Weidensaul – Ornithologist and naturalist and author of “A World on the Wing: the Global Odyssey of Migratory Birds.”
Kassandra Ford – Doctoral candidate in evolutionary biology at the University of Louisiana at Lafayette.
Michelle Nijhuis – Science journalist and author of “Beloved Beasts: Fighting for Life in an Age of Extinction.”
Originally aired May 10, 2021
Featuring music by Dewey Dellay and Jun Miyake
You can get early access to ad-free versions of every episode by joining us on Patreon. Thanks for your support!
Big Picture Science is part of the Airwave Media podcast network. Please contact advertising@airwavemedia.com to inquire about advertising on Big Picture Science.
 
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For the Birds*

The zombie eco-thriller “The Last of Us” has alerted us to the threats posed by fungi. But the show is not entirely science fiction. Our vulnerability to pathogenic fungi is more real than many people imagine. 
Find out what human activity drives global fungal threats, including their menace to food crops and many other species. Our high body temperature has long kept lethal fungi in check; but will climate change cause fungi to adapt to warmer temperatures and threaten our health? 
Plus, a radically new way to think about these organisms, how they make all life possible, and how we might find balance again.
Guests:
Emily Monosson – Toxicologist who writes about changes in the natural world. A member of the Ronin Institute and a professor at the University of Massachusetts, Amherst, she is the author of “Blight: Fungi and the Coming Pandemic.”
Arturo Casadevall – Microbiologist, immunologist, professor of medicine at Johns Hopkins School of Medicine.
Michael Hathaway – Anthropologist, director of the Asian Studies Center at Simon Fraser University in Vancouver, Canada, and author of “What a Mushroom Lives For.”
 *originally aired February 13, 2023
Big Picture Science is part of the Airwave Media podcast network. Please contact sales@advertisecast.com to inquire about advertising on Big Picture Science.
You can get early access to ad-free versions of every episode by joining us on Patreon. Thanks for your support!
 
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Fungi Fear*

Drinking a cup of coffee is how billions of people wake up every morning. But climate change is threatening this popular beverage. Over 60% of the world’s coffee species are at risk of extinction. Scientists are searching for solutions, including hunting for wild, forgotten coffee species that are more resilient to our shifting climate. Find out how the chemistry of coffee can help us brew coffee alternatives, and how coffee grounds can be part of building a sustainable future.
Guests:
Christopher Hendon - Assistant Professor of Computational Materials Chemistry, University of Oregon
Shannon Kilmartin-Lynch - Associate Professor of Civil Engineering, Monash University, Australia
Aaron Davis - Senior Research Leader of Crops and Global Change, Royal Botanical Gardens, Kew
Featuring music by Dewey Dellay and Jun Miyake
You can get early access to ad-free versions of every episode by joining us on Patreon. Thanks for your support!
Big Picture Science is part of the Airwave Media podcast network. Please contact advertising@airwavemedia.com to inquire about advertising on Big Picture Science.
 
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Vaccine, When?

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