Researchers and regulatory agencies are racing against the clock to develop a safe and effective vaccine against COVID-19. This episode outlines the path of vaccine development, the top contenders currently in phase 3 trials, as well as questions that remain unanswered.

• Intro :08
• The path of vaccine development 2:55
• Regulatory agencies working on a vaccine 4:09
• The lifecycle of vaccines 7:43
• Potential targets of the vaccines 10:58
• Top contenders in phase 3 trials 14:13
• Viral vector vaccines 21:03
• Protein-based vaccines 23:31
• Approval process 25:46
• Vaccine safety monitoring 28:23
• Unanswered questions 31:09
• Let's stay tuned for more information 33:12
• A fairytale analogy to explain vaccine development difficulties 35:10

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Disclosures: Pai reports serving on the advisory boards of Abbvie and Gilead Sciences.