No. 3 Texas Longhorns (-12.5) at Arkansas Razorbacks, Noon ET, ABC
Texas hasn’t had a dominant win yet, though their schedule hasn’t challenged them much. Arkansas, coming off a bye, has been struggling but won’t roll over at home. They could keep it close or even pull off an upset.
Pick: Arkansas +12.5
No. 20 Clemson Tigers (-11.5) at Pitt Panthers, Noon ET, ESPN
Pitt has struggled recently, but Clemson hasn’t been flawless either. While logic points to Clemson, Pitt’s home advantage and potential to rebound make them worth the points.
Pick: Pitt +11.5
Utah Utes (+11.5) at No. 17 Colorado Buffaloes, Noon ET, FOX
Colorado has improved on both sides of the ball, but Utah’s gritty, close-game style could challenge them. Kyle Whittingham may have something up his sleeve for this one.
Pick: Utah +11.5
Virginia Cavaliers (+23.5) at No. 8 Notre Dame Fighting Irish, 3:30 p.m. ET, NBC
Notre Dame has been dominant recently and is one of the best ATS teams under Marcus Freeman. Still, taking Virginia feels like a gamble worth trying.
Pick: Virginia +23.5
Boston College Eagles (+19.5) at No. 14 SMU Mustangs, 3:30 p.m. ET, ESPN
SMU’s path to an ACC title has opened up, and with Thomas Castellanos out for Boston College, SMU should roll.
Pick: SMU -19.5
No. 23 Missouri Tigers (+14.5) at No. 21 South Carolina Gamecocks, 4:15 p.m. ET, SEC Network
South Carolina’s defense at home should handle a Missouri team that has struggled to replicate last year’s success.
Pick: South Carolina -14.5
No. 1 Oregon Ducks (-13.5) at Wisconsin Badgers, 7:00 p.m. ET, NBC
Oregon faces a tough road test in Madison. The Badgers, fresh off a blowout loss to Iowa, could make this closer than expected. November challenges like this can define champions.
Pick: Wisconsin +13.5
No. 7 Tennessee Volunteers (+9.5) at No. 12 Georgia Bulldogs, 7:30 p.m. ET, ABC
Georgia has the edge, but Tennessee’s uncertainty, especially with Nico’s post-concussion play, makes this a tricky pick. Still, Georgia seems better positioned to cover.
Pick: Georgia -9.5
UAB Blazers (+15.5) at Memphis Tigers, 8:00 p.m. ET, ESPN2
Memphis has been inconsistent, while UAB can score. This could be closer than expected and is a more entertaining watch than the Georgia game.
Pick: UAB +15.5
Kansas Jayhawks (+2.5) at No. 6 BYU Cougars, 10:15 p.m. ET, ESPN
BYU has lived on the edge this season, but Kansas feels primed for an upset. The line suggests this could be their week.
Pick: Kansas +2.5
DK Saturday Main Slate DFS PicksRecord Year to Date: 19 Wins 25 Ties 21 Losses
Quarterback
Riley Leonard, Notre Dame ($9,500) – Leonard checks every box this week: mobile QB, home favorite, and facing a weak Virginia pass defense. With 13 rushing touchdowns this season and a 35+ point team total, Leonard has slate-breaking potential.
Cade Klubnik, Clemson ($8,600) – Klubnik has been consistent, with three or more TDs in six of nine games. Facing Pitt’s struggling secondary, he’s a reliable play, bolstered by Clemson’s emerging young receivers.
Running Back
Isaac Brown, Louisville ($6,700) – Brown is a lock, averaging 24+ fantasy points per game since taking over six weeks ago. Louisville’s run-heavy offense and a favorable matchup make him a must-play.
Kaytron Allen, Penn State ($4,900) – With Nick Singleton possibly limited or out, Allen becomes a high-volume play. If Singleton sits, Allen is a lock for 20+ carries at a great value.
Wide Receiver
Will Sheppard, Colorado ($3,600) – Sheppard has stepped up in Colorado’s pass-heavy offense, especially after Jimmy Horn’s injury. With touchdowns in four of five games, he’s the best value option.
TJ Moore, Clemson ($3,200) – Moore has emerged as a consistent target in Clemson’s offense, with two touchdowns and strong yardage in recent games. His low price and upside make him an excellent salary saver.
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No. 3 Texas Longhorns (-12.5) at Arkansas Razorbacks, Noon ET, ABC
Texas hasn’t had a dominant win yet, though their schedule hasn’t challenged them much. Arkansas, coming off a bye, has been struggling but won’t roll over at home. They could keep it close or even pull off an upset.
Pick: Arkansas +12.5
No. 20 Clemson Tigers (-11.5) at Pitt Panthers, Noon ET, ESPN
Pitt has struggled recently, but Clemson hasn’t been flawless either. While logic points to Clemson, Pitt’s home advantage and potential to rebound make them worth the points.
Pick: Pitt +11.5
Utah Utes (+11.5) at No. 17 Colorado Buffaloes, Noon ET, FOX
Colorado has improved on both sides of the ball, but Utah’s gritty, close-game style could challenge them. Kyle Whittingham may have something up his sleeve for this one.
Pick: Utah +11.5
Virginia Cavaliers (+23.5) at No. 8 Notre Dame Fighting Irish, 3:30 p.m. ET, NBC
Notre Dame has been dominant recently and is one of the best ATS teams under Marcus Freeman. Still, taking Virginia feels like a gamble worth trying.
Pick: Virginia +23.5
Boston College Eagles (+19.5) at No. 14 SMU Mustangs, 3:30 p.m. ET, ESPN
SMU’s path to an ACC title has opened up, and with Thomas Castellanos out for Boston College, SMU should roll.
Pick: SMU -19.5
No. 23 Missouri Tigers (+14.5) at No. 21 South Carolina Gamecocks, 4:15 p.m. ET, SEC Network
South Carolina’s defense at home should handle a Missouri team that has struggled to replicate last year’s success.
Pick: South Carolina -14.5
No. 1 Oregon Ducks (-13.5) at Wisconsin Badgers, 7:00 p.m. ET, NBC
Oregon faces a tough road test in Madison. The Badgers, fresh off a blowout loss to Iowa, could make this closer than expected. November challenges like this can define champions.
Pick: Wisconsin +13.5
No. 7 Tennessee Volunteers (+9.5) at No. 12 Georgia Bulldogs, 7:30 p.m. ET, ABC
Georgia has the edge, but Tennessee’s uncertainty, especially with Nico’s post-concussion play, makes this a tricky pick. Still, Georgia seems better positioned to cover.
Pick: Georgia -9.5
UAB Blazers (+15.5) at Memphis Tigers, 8:00 p.m. ET, ESPN2
Memphis has been inconsistent, while UAB can score. This could be closer than expected and is a more entertaining watch than the Georgia game.
Pick: UAB +15.5
Kansas Jayhawks (+2.5) at No. 6 BYU Cougars, 10:15 p.m. ET, ESPN
BYU has lived on the edge this season, but Kansas feels primed for an upset. The line suggests this could be their week.
Pick: Kansas +2.5
DK Saturday Main Slate DFS PicksRecord Year to Date: 19 Wins 25 Ties 21 Losses
Quarterback
Riley Leonard, Notre Dame ($9,500) – Leonard checks every box this week: mobile QB, home favorite, and facing a weak Virginia pass defense. With 13 rushing touchdowns this season and a 35+ point team total, Leonard has slate-breaking potential.
Cade Klubnik, Clemson ($8,600) – Klubnik has been consistent, with three or more TDs in six of nine games. Facing Pitt’s struggling secondary, he’s a reliable play, bolstered by Clemson’s emerging young receivers.
Running Back
Isaac Brown, Louisville ($6,700) – Brown is a lock, averaging 24+ fantasy points per game since taking over six weeks ago. Louisville’s run-heavy offense and a favorable matchup make him a must-play.
Kaytron Allen, Penn State ($4,900) – With Nick Singleton possibly limited or out, Allen becomes a high-volume play. If Singleton sits, Allen is a lock for 20+ carries at a great value.
Wide Receiver
Will Sheppard, Colorado ($3,600) – Sheppard has stepped up in Colorado’s pass-heavy offense, especially after Jimmy Horn’s injury. With touchdowns in four of five games, he’s the best value option.
TJ Moore, Clemson ($3,200) – Moore has emerged as a consistent target in Clemson’s offense, with two touchdowns and strong yardage in recent games. His low price and upside make him an excellent salary saver.
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