🧬 Can a diet improve healthspan without worsening frailty?

In this Cell Metabolism study, a low-protein longevity diet supplemented with moderate methionine reduced fat mass and frailty, preserved lean mass, improved insulin sensitivity, and increased GH, GLP-1, and FGF21 in aged mice. Western and ketogenic diets moved the needle the wrong way: more fat, more frailty, worse metabolic signals.

The clinical message: optimize protein quality and methionine balance—not extremes. 🌱⚖️

#Longevity #Healthspan #Frailty #Nutrition #MedicalPodcasts