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When most people think of Parkinson’s disease, the first images that come to mind are often hand tremors, muscle stiffness, and trouble walking. But what if the story starts long before those classic symptoms, sometimes decades earlier, with subtle clues like constipation, loss of smell, or unusual sleep disturbances? In this episode of “What I’d Tell My Family,” Dr. Todd Levine unveils the hidden early signs of Parkinson’s that often go unnoticed, reveals the latest research on how the disease can quietly begin in the gut or body before reaching the brain, and shares what he’d want his own loved ones to know about early risks, prevention, and the groundbreaking ways we can now detect Parkinson’s before it ever affects movement. Whether you’re concerned about a loved one, curious about cutting-edge science, or just want to demystify this complex disease, this conversation brings practical advice and hope for the future.
Timestamps:
00:00 Theories on Parkinson's disease origins
04:36 Early signs of Parkinson's disease
08:55 Constipation linked to Parkinson's research
10:18 Early diagnosis and preventative neurology
16:11 Detecting proteins linked to Parkinson's
18:10 Speeding up Parkinson's drug trials
21:54 The era of preventative neurology
24:20 Early warning signs of Parkinson's
Dr. Todd Levine on LinkedIn - https://www.linkedin.com/in/todd-levinemd/
FOX10 Talks: World Alzheimer’s Day - Part 1 & Part 2
Neuro Concierge - https://neuro-concierge.com/
Podcast - https://what-id-tell-my-family.beam.ly/
What I´d Tell My Family Podcast on LinkedIn - https://www.linkedin.com/company/what-id-tell-my-family/
Podcast Partner - https://www.tophealth.care/
Book - Your Brain's Second Chance by Dr. Todd Levine
“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”
Welcome back to What I'd Tell My Family, the show where renowned neurologist Dr. Todd Levine answers your most pressing questions about brain and nerve health, the same way he would for his loved ones. In this special episode, Dr. Levine discusses his new book, Your Brain's Second Chance, co-authored with his wife Samantha, which challenges the idea that cognitive decline is inevitable. You'll hear how the latest advances in preventative neurology, lifestyle choices, and emerging biomarkers are reshaping our ability to protect and even optimize our brains as we age. Dr. Todd Levine shares insights from decades of experience, practical advice on sleep, diet, exercise, and stress management, and reveals why taking an active role in our brain health matters now more than ever. Whether you're concerned about family history or simply want to boost your cognitive health, this conversation offers hope and actionable steps for every listener.
Timestamps:
00:00 Preventative neurology and biomarkers
03:59 Father-in-law's health journey
08:44 Maintaining brain health as we age
11:39 Importance of REM sleep for brain health
15:30 Brain health and social interaction
18:04 Book offers tools for healthy lifestyle
21:01 Wrapping up the episode
Dr. Todd Levine on LinkedIn - https://www.linkedin.com/in/todd-levinemd/
FOX10 Talks: World Alzheimer’s Day - Part 1 & Part 2
Neuro Concierge - https://neuro-concierge.com/
Podcast - https://what-id-tell-my-family.beam.ly/
What I´d Tell My Family Podcast on LinkedIn - https://www.linkedin.com/company/what-id-tell-my-family/
Podcast Partner - https://www.tophealth.care/
Book - Your Brain's Second Chance by Dr. Todd Levine
“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”
Welcome back to What I’d Tell My Family. In today’s episode, Dr. Todd Levine explores a frequently misunderstood and commonly misdiagnosed condition: dementia with Lewy bodies. Affecting over a million Americans, this form of dementia stands out for its early visual hallucinations, fluctuating cognition, and symptoms that often mimic psychiatric disorders or even Alzheimer’s disease. Dr. Levine breaks down how Lewy body dementia is different at a cellular level, the warning signs families should watch for, and why accurate diagnosis is critical, not just for effective treatment, but to avoid dangerous drug reactions. Whether you have a loved one struggling with memory loss or want to learn about the latest advances in diagnosis and care, this episode offers expert advice and hope for planning a better quality of life, even after a difficult diagnosis.
Timestamps:
00:00 Understanding Lewy body dementia
06:06 Early symptoms of Lewy body dementia
09:52 Link between REM disorder and brain diseases
11:59 Early signs of Lewy body dementia
15:11 Alzheimer's misdiagnosis risks
18:58 Initial dementia evaluation process
24:45 Planning for a fulfilling future
27:59 Medications for Lewy body dementia
31:02 Diagnosing and tracking dementia progress
33:15 Upcoming episode on skin tests
Dr. Todd Levine on LinkedIn - https://www.linkedin.com/in/todd-levinemd/
FOX10 Talks: World Alzheimer’s Day - Part 1 & Part 2
Neuro Concierge - https://neuro-concierge.com/
Podcast - https://what-id-tell-my-family.beam.ly/
What I´d Tell My Family Podcast on LinkedIn - https://www.linkedin.com/company/what-id-tell-my-family/
Podcast Partner - https://www.tophealth.care/
Book - Your Brain's Second Chance by Dr. Todd Levine
“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”
Dementia is a word that often sparks fear and confusion, with many families immediately thinking of Alzheimer’s as the only form. But dementia is actually an umbrella term for several distinct diseases, each with its own causes, symptoms, treatments, and risks. In this episode of "What I'd Tell My Family," Dr. Todd Levine guides us through the essential differences between the four major types of dementia: Alzheimer's disease, Lewy body dementia, frontotemporal dementia, and vascular dementia.
We'll explore how new diagnostic tools and FDA-approved treatments are making precision medicine possible, learn about the frequently missed or misdiagnosed forms like Lewy body dementia, and discover why getting the right diagnosis has never been more important. Whether you’re noticing early memory slips in a loved one or want to prepare for the future, Dr. Levine offers practical advice, discusses life-changing medication risks, and explains the importance of new biomarkers that could change how we fight these diseases. If you think all dementias are the same, this episode will give you the critical distinctions every family needs to know.
Timestamps:
00:00 Precision medicine in dementia care
04:40 Understanding Alzheimer's protein buildup
07:15 Understanding brain aging stages
11:09 Understanding Dementia with Lewy Bodies
16:38 Aggression in frontotemporal dementia
19:39 Addressing Cognitive Decline Risks
22:26 Understanding co-pathology in dementia
23:54 Precision medicine for dementia treatment
28:25 Diagnosing neurological conditions over time
32:20 Early diagnosis and intervention
33:35 Advancements in Alzheimer's diagnostics
Dr. Todd Levine on LinkedIn - https://www.linkedin.com/in/todd-levinemd/
FOX10 Talks: World Alzheimer’s Day - Part 1 & Part 2
Neuro Concierge - https://neuro-concierge.com/
Podcast - https://what-id-tell-my-family.beam.ly/
What I´d Tell My Family Podcast on LinkedIn - https://www.linkedin.com/company/what-id-tell-my-family/
Podcast Partner - https://www.tophealth.care/
Book - Your Brain's Second Chance by Dr. Todd Levine
“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”
Welcome back to "What I'd Tell My Family." In today’s episode, we take a deep dive into one of the least discussed, yet most powerful predictors in neurology: the APOE4 gene and its connection to Alzheimer’s disease. Joined by Dr. Todd Levine, we unravel what it means to carry APOE4, the difference between having one or two copies, and how genetic information can shape the way we approach risk, prevention, and family conversations about memory loss.
We address the big questions: Who should get tested for APOE4? What does a positive or negative result actually mean? How can lifestyle changes and new advances in blood-based biomarkers impact your long-term brain health? And how should families navigate the complex emotions and decisions that come with learning about genetic risk?
Whether Alzheimer’s is part of your family story or you just want to better understand the role of genetics in dementia, this episode provides grounded advice, expert insight, and the candid conversation most clinics skip. Grab a seat at the table; this is information every family should hear.
Timestamps:
00:00 Understanding genes and proteins basics
05:00 Understanding the APOE Protein Function
08:57 Answering the "so what" question
12:02 Discussing Alzheimer's risk and prevention
14:16 Discussing Alzheimer's risk and treatments
20:17 Understanding genetic risk and biomarkers
21:53 Discussing genetic testing decisions
25:16 Discussing APOE and Alzheimer's treatment
27:30 Ending the conversation
Dr. Todd Levine on LinkedIn - https://www.linkedin.com/in/todd-levinemd/
FOX10 Talks: World Alzheimer’s Day - Part 1 & Part 2
Neuro Concierge - https://neuro-concierge.com/
Podcast - https://what-id-tell-my-family.beam.ly/
What I´d Tell My Family Podcast on LinkedIn - https://www.linkedin.com/company/what-id-tell-my-family/
Podcast Partner - https://www.tophealth.care/
Book - Your Brain's Second Chance by Dr. Todd Levine
“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”
Welcome to What I'd Tell My Family. In today’s episode, Dr. Todd Levine demystifies the latest advances in Alzheimer’s diagnosis, specifically, the new blood tests that can spot warning signs years before symptoms appear. These groundbreaking tests are creating buzz everywhere from the New York Times to CNN, but what do they actually mean for you and your family? Dr. Todd Levine will walk us through the science behind these biomarkers, explain who should consider getting tested, and share the honest guidance he’d give his own loved ones when faced with tough decisions. No hype, no sugarcoating, just practical information and real talk to help you navigate the new era of Alzheimer’s prevention and care.
Timestamps:
00:00 FDA approves Alzheimer's blood test
04:12 Detecting Alzheimer's with P Tau 217
10:26 Understanding Alzheimer's Risk Factors
12:36 Determining Alzheimer's with blood tests
15:18 Emerging Alzheimer's treatments and trials
18:25 Advantages of P Tau 217 test
23:38 Discussing Alzheimer’s treatment options
25:48 Discussing genetics and dementia testing
28:21 Value of proactive health testing
31:35 Discussing Alzheimer's blood tests
Dr. Todd Levine on LinkedIn - https://www.linkedin.com/in/todd-levinemd/
FOX10 Talks: World Alzheimer’s Day - Part 1 & Part 2
Neuro Concierge - https://neuro-concierge.com/
Podcast - https://what-id-tell-my-family.beam.ly/
What I´d Tell My Family Podcast on LinkedIn - https://www.linkedin.com/company/what-id-tell-my-family/
Podcast Partner - https://www.tophealth.care/
Book - Your Brain's Second Chance by Dr. Todd Levine
“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”
Have you ever left a neurologist’s office with more questions than answers? Or struggled with a diagnosis that felt like the end of the road instead of a new beginning? On this premiere episode of What I’d Tell My Family, host and renowned neurologist Dr. Todd Levine to uncover the philosophy that drives his uniquely patient-centered approach to care. Drawing on decades of experience and his own journey as a patient—Dr. Todd Levine explains why every recommendation he gives starts with two fundamental questions: what does the science say, and what would I do if this were my own family? Together, they explore the challenges in today’s medical system, the importance of meaningful conversation and connection, and practical ways both patients and doctors can work as a team—especially when facing difficult neurologic diseases like ALS, Parkinson’s, and Alzheimer’s. Whether you’re seeking hope, better answers, or a more personal approach to brain health, this episode sets the stage for an enlightening look at what compassionate, individualized neurology truly means.
00:00 Personal health journey insights
04:20 Honoring patient's final wishes
09:14 Early detection in concierge medicine
13:33 Comprehensive patient health evaluation
17:49 Importance of gradual physical activity
18:56 Improving Health Through Exercise and Nutrition
24:39 Experiences as patient and caregiver
25:27 Simplifying complex neurologic diseases
29:31 Improving patient outcomes in neurology
Dr. Todd Levine on LinkedIn - https://www.linkedin.com/in/todd-levinemd/
FOX10 Talks: World Alzheimer’s Day - Part 1 & Part 2
Neuro Concierge - https://neuro-concierge.com/
Podcast - https://what-id-tell-my-family.beam.ly/
What I´d Tell My Family Podcast on LinkedIn - https://www.linkedin.com/company/what-id-tell-my-family/
Podcast Partner - https://www.tophealth.care/
Book - Your Brain's Second Chance by Dr. Todd Levine
“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”
From the publisher's feed
In every episode, Dr. Todd Levine - neurologist and founder of Neuro Concierge - picks up one real question about the brain and nerves and answers it the way he'd answer it for someone he loves.…