You’re eating clean.
You’re exercising regularly.
You’re disciplined, motivated, and doing exactly what you’ve been told to do.

So why isn’t the scale moving?

In this episode of the Dr. Lori Integrative Medicine Podcast, Dr. Lori explains why weight loss resistance is one of the most common — and misunderstood — health issues today, especially for women over 35 and high-performing adults.

If you’ve been stuck thinking “This used to work, but now it doesn’t,” this episode will change how you understand your body.

This isn’t about eating less or working harder.
It’s about hormones, inflammation, stress physiology, toxins, gut health, sleep, and metabolic adaptation — the real drivers of fat loss that are often ignored.

In this episode, Dr. Lori breaks down:

Why calorie restriction can actually slow fat loss

How cortisol, thyroid dysfunction, and insulin resistance block progress

The role of perimenopause and menopause in changing metabolism

Why inflammation and toxin exposure keep the body in fat-storage mode

Which labs actually matter when weight won’t budge

What to do differently if you’re “doing everything right”

This episode is for anyone who feels frustrated, blamed, or dismissed when weight loss stalls — and is ready for a smarter, root-cause approach.

00:00 – Introduction
Why weight loss resistance is not a willpower problem

02:15 – “I’m Doing Everything Right” Syndrome
Why disciplined people struggle the most with stalled weight loss

05:40 – Why Calories In vs. Calories Out Fails
How metabolic adaptation slows fat loss over time

09:30 – Cortisol, Stress, and Fat Storage
Why chronic stress keeps your body in survival mode

13:45 – Thyroid Function and Reverse T3
Why “normal” thyroid labs can still mean a sluggish metabolism

18:10 – Insulin Resistance You Can’t See
How blood sugar and insulin block fat loss even without diabetes

22:50 – Leptin Resistance and Hunger Signals
Why your body stops responding to fullness cues

27:15 – Perimenopause, Menopause, and Weight Gain
How hormonal shifts change the rules after 35–40

32:40 – Inflammation and Weight Loss Resistance
Why your body won’t release fat when it’s inflamed

36:55 – Toxins, Mold, and Metabolism
How environmental exposures quietly disrupt hormones and fat burning

41:30 – The Labs That Actually Matter
What to test when weight loss stalls

46:10 – What to Do Instead
A smarter, integrative approach to fat loss

50:00 – Final Takeaway
Why your body isn’t broken — it’s protecting you

If this episode resonated with you:

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Visit Dr. Lori Integrative Medicine to learn how functional labs can uncover your root cause

You don’t need more discipline.
You need better data — and a better plan.