This episode is brought to you by Maui Nui, Levels, and Ollie.

When we think about chronic disease and vital organs, the liver isn’t always the first that comes to mind—but it should be. The liver plays a role in nearly every metabolic process in the body, from stabilizing blood sugar levels to converting amino acids into usable fuel. Today’s guest joins the podcast for a deep dive into how optimizing liver health is key to supporting overall health.

Today on The Dhru Purohit Show, Dhru sits down with Kristin Kirkpatrick to explore the liver’s vital role in detoxification, the rise of fatty liver disease, and how liver health impacts overall mortality. They break down the connection between diet and liver function, debunk myths about dietary fat, and examine the effects of ultra-processed foods and artificial sweeteners. Kristin shares the benefits of coffee, muscle mass, and blood sugar balance for metabolic health, along with key liver-supportive foods, lifestyle tips, and insights into GLP-1 medications for those with obesity and liver issues.

In this episode, Dhru and Kristin dive into:

Also mentioned in this episode:

For more on Kristin, follow her on Facebook, Instagram, X/Twitter, Pinterest, Youtube, LinkedIn, and her Website.

This episode is brought to you by Maui Nui, Levels, and Ollie. 

Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now —but hurry, supply is limited!

Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link: levels.link/DHRU. Make moves on your metabolic health with Levels today.

Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com, use the code DHRU, and you’ll get 60% off your first box of meals in your subscription.

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This episode is brought to you by Momentous, Cozy Earth, and Levels.

In today’s world, addiction takes many forms—whether it’s alcohol, drugs, social media, or people-pleasing. Certain key factors drive these behaviors and make breaking the cycle incredibly challenging. Today’s guest offers powerful insights into brain health and psychology, explaining why these patterns emerge and how we can begin to unhook from them.

On this episode of The Dhru Purohit Show, Dhru sits down with psychologist and addiction expert Dr. Adi Jaffe. Dr. Jaffe breaks down the “hook” that keeps us stuck in addictive behaviors and explores the root causes that draw us back to them. He takes a deep dive into shame—the true fuel behind addiction—and explains why people-pleasing is one of the hardest patterns to break. He also shares his own powerful journey of overcoming addiction and highlights the importance of holding onto beliefs that serve us—and letting go of those that don’t.

Dr. Adi Jaffe is a UCLA-trained psychologist and a leading expert on mental health, addiction, and relationships. Once a meth addict and drug dealer, his life changed after a SWAT arrest and jail sentence. Now the author of The Abstinence Myth and Unhooked, Dr. Jaffe challenges traditional addiction treatment and leads IGNTD, an organization helping former inmates find support for addiction and mental health. His work has been featured on CNN, Fox, NBC, and Psychology Today.

In this episode, Dhru and Dr. Jaffe dive into:

Also mentioned in this episode:

For more on Dr.Jaffe, follow him on Facebook, Instagram, X/Twitter,  Apple Podcast, LinkedIn, his Website, and other platforms, such as IGNTD™.

This episode is brought to you by Momentous, Cozy Earth, and Levels,

Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Head to livemomentous.com and use code DHRU for 35% off your first subscription.

Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP.

Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link, levels.link/DHRU. Make moves on your metabolic health with Levels today.

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This episode is brought to you by Levels and Maui Nui.

When most people think about metabolic health, they think of weight management and steady energy. But here’s what often gets overlooked: metabolic health also plays a major role in sexual function and fertility.

Our hormones depend on a delicate balance—and when blood sugar spikes and crashes, that balance gets thrown off. The result? Not just weight gain, mood swings, and fatigue, but also a higher risk of erectile dysfunction, infertility, reduced sexual pleasure, and more.

Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with experts on how sexual health can reflect your overall metabolic health.

Dr. Casey Means explains that blood flow, hormones, and psychology are the three pillars of good sexual function. She shares how diet impacts all three through a hormonal cascade, along with effects on nitric oxide and neurotransmitter production.

Dr. Rena Malik dives into the importance of a healthy sex life and the common challenges men and women face—from low libido and hormone imbalances to lifestyle factors that get in the way. She breaks down the science behind sexual health, including the roles of diet, exercise, and orgasms, and unpacks the key roadblocks that can prevent us from experiencing a truly fulfilling sex life.

Dr. Casey Means is a Stanford-trained physician, Co-founder of the metabolic health company Levels, and author of Good Energy. Her mission is to maximize human potential and reverse the epidemic of preventable chronic disease by empowering individuals with tools that foster a deep understanding of their bodies and support personalized, sustainable dietary and lifestyle choices.

Dr. Rena Malik is a board-certified urologist with a talent for dispelling medical misinformation, discussing intimate topics, and evidence-based discussions of taboo topics. Dr. Malik is also a  prominent reconstructive urologist treating bladder conditions, sexual dysfunction, pelvic pain, and hormone management.

In this episode, Dhru and his guests dive into:

Also mentioned:

This episode is brought to you by Levels and Maui Nui. 

Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link: levels.link/DHRU. Make moves on your metabolic health with Levels today.

Right now Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now —but hurry, supply is limited!

Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Levels, BiOptimizers, and Birch Living. 

Traditionally, elevated LDL has been directly linked to a higher risk of cardiovascular disease. But today’s guest is on a mission to dig deeper. He’s raising both awareness and funding to explore the true relationship between LDL, ApoB, and heart disease—challenging long-held beliefs in the process. He joins us to share the results of his team’s groundbreaking study.

Today on The Dhru Purohit Show, Dhru sits down with Dave Feldman to discuss his team’s landmark study on LDL cholesterol and its implications for cardiovascular health. Dave shares the personal journey that led him to fund this research and what it means for how we approach and treat heart disease. He breaks down the surprising findings on how plaque progression really occurs—and the key questions that still need answers in future studies. Dave also outlines the most effective tests to assess your risk, along with how to interpret your scores based on age.

Dave Feldman is a software and platform engineer, entrepreneur, and founder of the Citizen Science Foundation. His life took a radical turn upon seeing his cholesterol skyrocket after adopting a ketogenic diet, and he became obsessed with understanding why this is common with those who are likewise leaner and more metabolically healthy. Through a series of self-experiments and partnering with formal researchers, he has since published the “Lipid Energy Model,” which may explain this phenomenon.

In this episode, Dhru and Dave dive into:

Also mentioned in this episode:

For more on Dave, follow him on Instagram, Twitter/X, YouTube, his Website, and other platforms, such as Cholesterol Code.

This episode is brought to you by Levels, BiOptimizers, and Birch Living.

Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link: levels.link/DHRU. Make moves on your metabolic health with Levels today.

Go to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order of Sleep Breakthrough and find out this month’s gift with purchase. 

Get 20% off your Birch Living mattress during their Spring Event—just head to birchliving.com/dhru today! 

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This episode is brought to you by LMNT and Lumebox. 

The mainstream narrative around LDL cholesterol has long claimed that high LDL is always harmful—no matter the individual or their overall health status. The traditional view holds that elevated LDL levels directly increase the risk of cardiovascular disease, regardless of metabolic health. Today’s guest, Dr. Nick Norwitz, shares groundbreaking research that further explains why plaque buildup progresses and how it can lead to heart disease. 

Today on The Dhru Purohit Show, Dhru sits down with Dr. Nick Norwitz to explore a groundbreaking study on LDL cholesterol and its implications for cardiovascular health. Dr. Norwitz dives into the role of diet, individual risk factors, and the significance of plaque progression while also addressing lifestyle influences and practical strategies for heart health. He also shares insights on the limitations of current testing methods, the impact of microplastics on cardiovascular health, and the growing gut health crisis. Dhru and Dr. Norwtiz emphasized the need for personalized nutrition, informed decision-making, and a balanced perspective between scientific research and real-world experience.

Dr. Nick Norwitz is a researcher, educator, and passionate advocate for metabolic health whose mission is to “Make Metabolic Health Mainstream.” He earned a PhD in Metabolism from the University of Oxford and is now completing his MD at Harvard Medical School. Nick’s drive in this field stems from his personal battle with severe Inflammatory Bowel Disease, which he overcame through a ketogenic diet after conventional treatments failed. His journey has fueled a deep commitment to challenging outdated thinking around health, and he’s known for his infectious curiosity and dedication to teaching.

In this episode, Dhru and Dr. Norwitz dive into:

Also mentioned in this episode:

For more on Dr. Norwitz, follow him on Facebook, Instagram, X/Twitter, YouTube, LinkedIn, Threads, and his Website, and subscribe to his Newsletter.

This episode is brought to you by LMNT and Lumebox.

Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to drinkLMNT.com/dhru today.

Lumebox is offering my community $260 off their FDA-registered portable Red Light device!  That's over 40% off! Go to thelumebox.com/dhru and get your Red Light device.

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This episode is brought to you by Bon Charge, Pique Life, and Fatty15.

When it comes to looking younger, sun exposure, and skin cancer, the research and advice can be overwhelming, leaving many of us unsure of what to believe. With endless skincare products and trends flooding the market, it’s hard to know what’s truly effective, worth the investment, and safe for maintaining a youthful glow. Today’s guest joins us to break it all down and share what really works.

Today on The Dhru Purohit Show, Dhru sits down with double board-certified dermatologist and skin cancer and reconstructive surgery specialist Dr. Teo Soleymani to discuss research-backed skin protocols that can improve your skin and reduce your risk of skin cancer. Dr. Soleymani breaks down the difference between mineral and chemical sunscreens, what the data really says about sun exposure and skin cancer, and the top therapies for reducing wrinkles, acne scars, and sun damage. He also shares the most cost-effective devices and strategies for achieving a more youthful appearance.

Dr. Teo Soleymani is a nationally recognized, double board-certified dermatologist and fellowship-trained Mohs Micrographic and Facial Plastic & Reconstructive Surgeon. A Stanford-trained physician and former clinical professor at UCLA, he specializes in the treatment of complex, high-risk skin cancers and sun-damaged, aging skin. He now leads California Dermatology and Mohs Surgery Specialists in Pasadena, CA, and continues to contribute to academic research and innovation in dermatologic surgery.

In this episode, Dhru and Dr. Soleymani dive into:

Also mentioned in this episode:

• Sun Powder 

For more on Dr. Soleymani, follow him on Instagram, LinkedIn, and his Website.

This episode is brought to you by Bon Charge, Pique, and Fatty15.

Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%.

Right now, Pique Life is offering 20% off the Radiant Skin Duo plus a free beaker and frother when you go to piquelife.com/dhru.

Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health.

Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Birch Living and Levels.

When you think of blood sugar regulation, weight loss, or boosting cognition, fiber may not be the first thing that comes to mind. But this essential nutrient does far more than just relieve constipation. It feeds our gut microbes, keeping them happy and thriving—and in return, they produce anti-inflammatory, anti-cancer, immune-supporting metabolites that help us stay healthy, happy, and thriving.

Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with top experts on fiber and its powerful benefits for gut and whole-body health. Dr. Will Bulsiewicz breaks down the signs of inadequate fiber in your diet and shares his top four tips for improving bowel movements and incorporating fiber into your daily routine. Dr. Mary Claire Haver explains how optimizing fiber intake can help reduce visceral fat—especially during perimenopause and menopause. Dr. Brad Stanfield highlights psyllium husk as one of the most underrated supplements for boosting fiber intake and supporting overall health.

Dr. Will Bulsiewicz is an award-winning gastroenterologist and New York Times bestselling author of Fiber Fueled and The Fiber Fueled Cookbook.

Dr. Mary Claire Haver is board-certified in Obstetrics and Gynecology and is a Certified Culinary Medicine Specialist. 

Dr. Brad Stanfield is a primary care physician hailing from Auckland, New Zealand who has garnered over 200,000 followers on YouTube for his video segments related to longevity-promoting strategies.

In this episode, Dhru and his guests dive into:

Also mentioned:

This episode is brought to you by Birch Living and Levels.

Get 25% off your Birch Living mattress during their Flash Sale—just head to birchliving.com/dhru today!

Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link, levels.link/DHRU. Make moves on your metabolic health with Levels today.

Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15.

When we think about treating depression, we rarely consider exercise. Yet emerging research shows it can be a powerful tool for managing mild to moderate depression, and it works well alongside other therapies—including medication. Today’s guest shares the science behind exercise and explores why more practitioners aren’t incorporating it into treatment conversations.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Nicholas Fabiano to explore the powerful role of exercise in treating depression. Dr. Fabiano introduces the FITT protocol for prescribing exercise and sheds light on the disconnect between physicians and patients when it comes to exercise recommendations. Dhru and Dr. Fabiano also discuss how research funding can shape treatment perspectives, the benefits of combining medication with lifestyle interventions, and the emerging role of creatine in brain energy and its potential impact on depression. Dr. Fabiano emphasizes why exercise is essential for mental health and advocates for a holistic approach to treating depression—one that includes lifestyle pillars like diet and sleep.

Nicholas Fabiano is a psychiatry resident and researcher at the University of Ottawa. Drawing from his personal background in weightlifting and competitive soccer, Nicholas developed a strong interest in the use of exercise as a treatment for mental disorders, particularly depression. His research focuses on the intersection of mental and physical health, with a special emphasis on lifestyle psychiatry—exploring how exercise, diet, and sleep influence mental well-being.

In this episode, Dhru and Dr. Fabiano dive into:

Also mentioned in this episode:

For more on Dr. Fabiano, follow him on Instagram, X/Twitter, LinkedIn, and his Website.

This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15.

Go to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order of Sleep Breakthrough and find out this month’s gift with purchase. 

Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP.

Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health.

Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Pique Life, Momentous, and Lumebox. 

When we think about disease and chronic illness, we don’t usually consider the possibility of a lab leak or a government experiment gone wrong. Today’s guest sheds light on her investigation into Lyme disease, its disturbing origins, and how it’s impacted patient treatment. 

Today on The Dhru Purohit Show, Dhru sits down with writer and producer Kris Newby to discuss her theory on the origins of Lyme disease. She explores the possible role of weaponized ticks, the mismanagement of Lyme disease treatment, and the implications of military secrecy surrounding biological experiments. Kris also emphasizes the need for a deeper understanding of Lyme disease’s complexity and its broader impact on public health. She highlights the importance of awareness, research, and advocacy for better treatment options while sharing her personal journey with Lyme disease and how it affected her family.

Kris Newby is an award-winning science writer and the senior producer of the Lyme disease documentary UNDER OUR SKIN, which premiered at the Tribeca Film Festival and was a 2010 Oscar semifinalist. Her book, BITTEN, won three international book awards for journalism and narrative nonfiction. Previously, she worked as a science and technology writer for Stanford Medical School, Apple, and other Silicon Valley companies. She is currently working on her second book.

In this episode, Dhru and Kris dive into:

Also mentioned in this episode:

For more on Kris, follow her on Instagram, Facebook, X/Twitter, LinkedIn, and her Website.

This episode is brought to you by Pique Life, Momentous, and Lumebox. 

Right now, Pique Life is offering 20% off the Radiant Skin Duo plus a free beaker and frother when you go to piquelife.com/dhru.

Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Go to livemomentous.com and enter promo code DHRU to get 20% off any order.

Lumebox is offering my community $260 off their FDA-registered portable Red Light device!  That's over 40% off! Go to thelumebox.com/dhru and get your Red Light device. 

Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by BiOptimizers, Our Place, and Manukora Honey.

Mental health disorders are on the rise in our modern world, as our brains and bodies face constant disruption from environmental toxins in the air, water, and food. Meanwhile, connection and stress look vastly different than they once did. Today’s guest sheds light on what has changed, why these disorders are increasing, and—most importantly—how to protect ourselves.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Drew Ramsey to discuss the current state of mental health and treatment. Dr. Ramsey breaks down the top lies we've been told about brain health and healing. He also explores the challenges of modern life, how they disrupt our brains and mental well-being, and the lifestyle habits that make these disruptions worse. Plus, he shares the optimal diet for reducing the risk of depression and neurodegenerative diseases, along with the powerful impact of journaling, spending time in nature, and building community.

Drew Ramsey, MD, is a board-certified integrative psychiatrist, best-selling author, and a leading proponent of Nutritional Psychiatry and Mental Fitness. He served as an Assistant Clinical Professor of Psychiatry at Columbia University’s Vagelos College of Physicians and Surgeons for twenty years. Dr. Ramsey founded the Brain Food Clinic in New York City and Spruce Mental Health in Jackson, WY. A sought-after speaker, he conducts workshops nationwide, and his work has been widely featured in the media.

In this episode, Dhru and Dr. Ramsey dive into:

Also mentioned in this episode:

For more on Dr. Ramsey, follow him on Instagram, Facebook, X/Twitter, and his Website.

This episode is brought to you by BiOptimizers, Our Place, and Manukora Honey.

Go to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order of Sleep Breakthrough and find out this month’s gift with purchase. 

Reduce your toxic load by upgrading your cookware! Go to fromourplace.com today and use promo code DHRU at checkout to receive 10% off any order.

Upgrade to the creamiest honey, packed with antioxidants and prebiotics. Just go to manukora.com/dhru to get $25 off the Starter Kit and boost your energy, immunity, and digestive health today!

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