Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare

Could calming overactive mast cells help with chronic fatigue, brain fog, and food reactivity? Dr. Ruscio explores remarkable improvements reported in a Johns Hopkins case series using cromolyn sodium—a mast cell stabilizer developed from the plant compound khellin. Learn how it works in the gut, dosing and safety considerations, and how it may help highly reactive patients tolerate treatment for underlying triggers.

✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

📖 Free Guides:

MCAS Guide & Questionnaire: https://drruscio.com/guides/get-mcas-symptom-questionnaire/

Histamine Intolerance: https://drruscio.com/guides/get-histamine-intolerance-guide/

💊 Featured Products:

NasalCrom Nasal Spray Allergy: https://www.amazon.com/dp/B000R829FO?lv=shuf&channelId=500&plpRedirect=mhFallback&th=1

👇 Watch more videos like this 👇

➡️ This New Histamine Treatment Helped 89% of Patients: https://www.youtube.com/watch?v=cosOYisG-bQ

➡️ 5 Warning Signs You're Histamine Intolerant (& What You Can Do): https://youtu.be/JPBAd9RzIf4?si=X-MXY1l7l71dDSe4

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇 Read these next 👇

➡️ Low Histamine Diet: Foods to Eat, Avoid, and a 3-Week Plan: https://drruscio.com/low-histamine-diet/

➡️ Can I Take Quercetin for Histamine Intolerance?: https://drruscio.com/quercetin-for-histamine-intolerance/

00:00 Intro

01:35 Cromolyn's Impact On Health

03:28 What Cromolyn Is

04:27 Patient Cases

06:49 Protocols Used In Cases

08:35 Gut & Other Benefits

10:00 Cromolyn & Root-Cause Treatment

12:28 Safety and Side Effects

13:15 Closing

📉https://pubmed.ncbi.nlm.nih.gov/41728426/

📉https://pubmed.ncbi.nlm.nih.gov/2110198/

📉https://pubmed.ncbi.nlm.nih.gov/2506913/

📉https://pubmed.ncbi.nlm.nih.gov/6405650/

📉https://pubmed.ncbi.nlm.nih.gov/37442295/

📉https://pubmed.ncbi.nlm.nih.gov/2141132/

📉https://pubmed.ncbi.nlm.nih.gov/6401954/

📉https://pubmed.ncbi.nlm.nih.gov/101315/

📉https://pubmed.ncbi.nlm.nih.gov/1742648/

Facebook - https://www.facebook.com/DrRuscio

Instagram - https://www.instagram.com/drruscio/

DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.

What happens when you drink kefir every day? In this video, Dr. Ruscio breaks down findings from 70+ clinical trials on this traditional fermented drink, including its potential effects on gut health, digestion, inflammation, metabolic health, and even brain function. He also covers how much kefir to drink, whether homemade or store-bought is better, and what to look for on the label.

✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

✅ Get practical, science-based insights straight to your inbox: https://drruscio.com/signup/

📖 Kefir Guides

How To Make Homemade Kefir: https://culturesforhealth.com/blogs/learn/milk-kefir-how-to-make-milk-kefir?srsltid=AfmBOorHufAS0ZLcH_xgznS4YBylr3EUs9sEYxdQPIQKiAgmZgBqZIO4&utm_

Recommended Kefir Grains:

https://culturesforhealth.com/collections/kefir/products/milk-kefir-grains

Healthy Gut Healthy You:

https://store.drruscio.com/products/healthy-gut-healthy-you

👇 Watch more videos like this 👇

➡️ 6 Fermented Foods You Must Eat for Better Gut Health: https://youtu.be/f-b16qAD4tI?si=-MdwGG_QDEpWyHvo

➡️ If I Could Only Take ONE Gut Health Supplement:

https://youtu.be/qrJwfWa2r9Y?si=uYqPquBPA6rnYs2T

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇 Read these next 👇

➡️ Are Probiotic Drinks as Effective as Probiotic Supplements?: https://drruscio.com/probiotic-drinks/

➡️ Types of Probiotics: https://drruscio.com/types-of-probiotics/

00:00 Intro

02:24 What is Kefir?

03:15 Gut Health

06:58 Lower Inflammation

08:21 Brain Health

10:00 Metabolic & Other Benefits

10:18 Homemade Kefir

11:00 Recommended Kefir Dose

11:33 Closing Thoughts

📉 https://pubmed.ncbi.nlm.nih.gov/41827605/

📉 https://www.frontiersin.org/journals/food-science-and-technology/articles/10.3389/frfst.2025.1725280/full

📉 https://pubmed.ncbi.nlm.nih.gov/40469719/

📉 https://pubmed.ncbi.nlm.nih.gov/42174008/

📉 https://pubmed.ncbi.nlm.nih.gov/32171508/

📉 https://pubmed.ncbi.nlm.nih.gov/25599776/

📉 https://pubmed.ncbi.nlm.nih.gov/30662004/

📉 https://pubmed.ncbi.nlm.nih.gov/42174008/

📉 https://pubmed.ncbi.nlm.nih.gov/41314291/

📉 https://www2.med.muni.cz/biomedjournal/pdf/2007/06/279-286.pdf

📉 https://pubmed.ncbi.nlm.nih.gov/37224566/

📉 https://pubmed.ncbi.nlm.nih.gov/23621727/

📉 https://pubmed.ncbi.nlm.nih.gov/35405603/

📉 https://pubmed.ncbi.nlm.nih.gov/41076330/

📉 https://pubmed.ncbi.nlm.nih.gov/35282787/

📉 https://pubmed.ncbi.nlm.nih.gov/32411323/

📉 https://pubmed.ncbi.nlm.nih.gov/30768439/

📉 https://pubmed.ncbi.nlm.nih.gov/41076330/

📉 https://www.sciencedirect.com/science/article/abs/pii/S2213434421000177

Facebook - https://www.facebook.com/DrRuscio

Instagram - https://www.instagram.com/drruscio/

DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.

💊 Dr. Ruscio Probiotics: https://store.drruscio.com/collections/probiotics

Not all probiotics are created equal, and even a good probiotic may not work if you're using the wrong formula, dose, or duration.

In this episode, Dr. Ruscio breaks down how to choose a high-quality probiotic, what GMP and third-party testing actually tell you, how long probiotics typically need to work, the most evidence-supported formula types and doses, and what to do if you're sensitive or don't respond.

✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

✅ Get practical, science-based insights straight to your inbox: https://drruscio.com/signup/

👇 Watch more videos like this 👇

➡️ Cure SIBO FASTER (New Research): https://youtu.be/u8MsOY5rgAU?si=cQtkEYfM-jwabFMi

➡️ Prebiotics vs Probiotics - Which Is Best for Gut Health?: https://www.youtube.com/watch?v=3Efllxhj3ts

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇Read these next 👇

➡️ How to Take Probiotics for the Best Results: https://drruscio.com/how-often-to-take-probiotics/

➡️ Do Probiotics Make You Poop?: https://drruscio.com/do-probiotics-make-you-poop/

➡️ What Happens When You Stop Taking Probiotics: Week by Week: https://drruscio.com/what-happens-when-you-stop-taking-probiotics/

00:00 Intro

01:51 Selecting Quality Probiotics

07:04 Probiotic Guidelines

13:55 Formula Types

18:01 Probiotic Meta-Protocol

19:36 Sensitivity, Side Effects & Caveats

23:23 Closing Thoughts

https://pubmed.ncbi.nlm.nih.gov/21303743/

https://pubmed.ncbi.nlm.nih.gov/40995173/

https://pubmed.ncbi.nlm.nih.gov/32582075/

https://pubmed.ncbi.nlm.nih.gov/27857709/

https://pubmed.ncbi.nlm.nih.gov/21303743/

https://pubmed.ncbi.nlm.nih.gov/31105649/

https://www.consumerlab.com/news/problems-at-supplement-manufacturing-sites/03-20-2020/?utm_

https://www.wired.com/story/creatine-gummies-dubious-claims/

https://pubmed.ncbi.nlm.nih.gov/36178333/

https://pubmed.ncbi.nlm.nih.gov/35927504/

https://pubmed.ncbi.nlm.nih.gov/41394228/

https://pubmed.ncbi.nlm.nih.gov/23299716/

https://pubmed.ncbi.nlm.nih.gov/29128720/

Facebook - https://www.facebook.com/DrRuscio

Instagram - https://www.instagram.com/drruscio/

DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.

In this episode, Dr. Ruscio and Dr. Scott Spiridigliozzi break down why mold and fungal treatments often fail—and what may improve the odds of success. They discuss how to get clearer on the diagnosis, why herbal therapies may not be enough for some patients, the importance of reaching therapeutic antifungal levels, why underdosing can backfire, and how targeting the right tissues may help prevent relapse. They also share insights from their own experiences with chronic fungal illness and how those lessons are shaping their evolving treatment approach.

✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

💊 Antifungal Protocol

🔹 Triple Therapy Probiotic Powder Sticks: https://store.drruscio.com/products/triple-therapy-probiotic

🔹 Gut Rebuild Nutrients: https://store.drruscio.com/products/gut-rebuild-nutrients-powder-chocolate

🔹 Biota-Boost: https://store.drruscio.com/products/biota-boost

🔹 Biota Resistant Starch: https://store.drruscio.com/products/biota-resistant-starch

🔹 Biota Fiber: https://store.drruscio.com/products/biota-fiber

🌿 Herbal Antimicrobials

🔹 Biota-Clear 1a: https://store.drruscio.com/products/biota-clear-1a

🔹 Biota-Clear 1b: https://store.drruscio.com/products/biota-clear-1b

🔹 Biota-Clear 2a: https://store.drruscio.com/products/biota-clear-2a

🔹 Biota-Clear 2b: https://store.drruscio.com/products/biota-clear-2b

👃 Nasal irrigation:

🔹 NeilMed Squeeze Bottle

https://shop.neilmed.com/products/sinus-rinse-bottle-3ct-and-nasadock-plus

🔹 NeilMed Xylitol

https://www.amazon.com/NeilMed-Sinus-Rinse-Xylitol-Count/dp/B08FPK73R7?th=1

🔹 NAC Packet

https://www.amazon.com/SinuMed-Packets-Allergy-Congestion-Symptoms/dp/B0FLPQFN99/

🔹 LiviaOne Probiotic Nasal Spray:

https://store.drruscio.com/products/liviaone-probiotic-nasal-spray

👇 Watch more videos like this 👇

➡️ Fungus – The Hidden Reason Symptoms Keep Coming Back:

https://www.youtube.com/watch?v=lIb2DXdInv4

➡️ How to Tell If You Have Mold in Your Home (And What To Do Next):

https://www.youtube.com/watch?v=utLr0rQghfs

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇 Read these next 👇

➡️ Everything You Need to Know about SIFO (Small Intestinal Fungal Overgrowth):

https://drruscio.com/everything-need-know-sifo-small-intestinal-fungal-overgrowth/

➡️ Black Mold Symptoms: What's Real, What's Not, and What to Do: https://drruscio.com/black-mold-symptoms/

00:00 Intro

05:25 Clues of Fungal Infection

10:32 Diagnostic Clarity

17:50 Herbal Therapy Alone Is Insufficient

19:36 Natural Fungal Protocol

23:46 Medications Must Hit Therapeutic Levels

35:56 Don't Be Timid On The Battlefield

55:35 Medications Must Hit Target Tissues

📉Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth: https://pubmed.ncbi.nlm.nih.gov/41394228/

📉Itraconazole solution: higher serum drug concentrations and better clinical response rates than the capsule formulation in acquired immunodeficiency syndrome patients with candidosis: https://pubmed.ncbi.nlm.nih.gov/9378812/

📉Population pharmacokinetics of itraconazole and its active metabolite hydroxy-itraconazole in paediatric cystic fibrosis and bone marrow transplant patients: https://pubmed.ncbi.nlm.nih.gov/17048974/

📉Effect of omeprazole on the pharmacokinetics of itraconazole: https://pubmed.ncbi.nlm.nih.gov/9626921/

📉Case Study: Rapid Complete Recovery From An Autism Spectrum Disorder After Treatment of Aspergillus With The Antifungal Drugs Itraconazole And Sporanox: https://pubmed.ncbi.nlm.nih.gov/33132781/

Facebook - https://www.facebook.com/DrRuscio

Instagram - https://www.instagram.com/drruscio/

DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.

Gallbladder removal may not always be the only option. In this video, Dr. Scott Spiridigliozzi explains how SIBO and gut dysbiosis may contribute to gallstones, sludge, and poor gallbladder function. He also shares two patient cases and the gut-focused protocol used to resolve their symptoms and help them avoid surgery.

✅ Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

💊 Supplement Protocol

• 📖Free Low FODMAP Diet Guide: https://drruscio.com/guides/get-low-fodmap-diet-guide/

• Triple Therapy Sticks: https://store.drruscio.com/products/triple-therapy-probiotic?variant=40164201922757

62 billion CFU per serving

• Dose range: 1-3 packets per day

• May be taken with or without food

• Herbal antimicrobials (SIBO Biofilm Protocol: https://drruscio.com/biofilm-protocol/)

• 1st month:

• Biota-Clear 1a: https://store.drruscio.com/products/biota-clear-1a?variant=31925255471156

4 pills, 2x per day, best with food. 2 bottles of 120 capsules needed per month

• Biota-Clear 1b: https://store.drruscio.com/products/biota-clear-1b?variant=5245784522789

2 pills, 2x per day, best with food. 2 bottles of 60 capsules needed per month

• 2nd month:

• Biota-Clear 2a: https://store.drruscio.com/products/biota-clear-2a?variant=4964993171493

3 pills, 2x per day, best with food. 2 bottles of 90 capsules needed per month

• Biota-Clear 2b: https://store.drruscio.com/products/biota-clear-2b?variant=5245785145381

3 pills, 2x per day, best with food. 2 bottles of 90 capsules needed per month

• Take along with antimicrobials:

• Biota Dissolve: https://store.drruscio.com/products/biota-dissolve

3 capsules, 2x per day, on an empty stomach

• Glycine: https://www.amazon.com/Life-Extension-Glycine-Vegetarian-Capsules/dp/B00B35A394/ref=sr_1_6

3 capsules 2x daily with or without food

• TUDCA: https://www.amazon.com/Supplement-Servings-Double-Wood-Supplements/dp/B07YQ6J6FW/ref=sr_1_4?th=1

1-2 caps 2x daily with food

• Optimal PC: https://www.amazon.com/Seeking-Health-Supplement-Phospholipid-Sunflower/dp/B00SLVJ54M/ref=sr_1_2

Start with 1 capsule 2x daily with food.

• Increase as tolerated to 3 caps 2x daily with food.

• Diarrhea can occur initially, and should improve over time. If it doesn't improve, lower the dose to whichever dose doesn't cause diarrhea.

👇 Watch more videos like this 👇

➡️ How to Get Rid of Gallstones Naturally: https://www.youtube.com/watch?v=Sm2ENwJ-F1g

➡️ Cure SIBO FASTER (New Research): https://www.youtube.com/watch?v=u8MsOY5rgAU

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇Read these next 👇

➡️ The 5 Most Evidence-Backed Gallstone Supplements: https://drruscio.com/gallstone-supplements/

00:00 Intro

01:47 Warning Signs

02:37 The Microbiome's Role

04:29 2 Types of Gut Imbalance

06:46 Patient Cases

09:44 Treatment Protocol

15:35 Patient Results

16:53 Key Takeaways

📉 Gastrointestinal microbiome and cholelithiasis: https://pubmed.ncbi.nlm.nih.gov/36970590/

📉 The characteristics of small intestinal bacterial overgrowth in patients with gallstone diseases:

https://pubmed.ncbi.nlm.nih.gov/29392773/

📉 Intestinal flora imbalance affects bile acid metabolism and is associated with gallstone formation: https://pubmed.ncbi.nlm.nih.gov/32143645/

📉 Effects of oral tauroursodeoxycholic acid and/or intestinal probiotics on serum biochemical indexes and bile composition in patients with cholecystolithiasis: https://pubmed.ncbi.nlm.nih.gov/36353477/

📉 Effects of oral tauroursodeoxycholic acid and/or intestinal probiotics on serum biochemical indexes and bile composition in patients with cholecystolithiasis: https://pubmed.ncbi.nlm.nih.gov/36353477/

📉 Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth: https://pubmed.ncbi.nlm.nih.gov/41394228/

📉 The effect of ursodeoxycholic acid in dissolving gallstones formed after laparoscopic sleeve gastrectomy: retrospective cohort study: https://pmc.ncbi.nlm.nih.gov/articles/PMC11885402/

Facebook - https://www.facebook.com/DrRuscio

Instagram - https://www.instagram.com/drruscio/

DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.

📖 Full Mold Checklist & Resources Guide (Free Download) : https://drruscio.com/guides/get-home-mold-guide/

Could hidden fungus or mold exposure be driving recurring gut symptoms? In this episode, Dr. Scott Spiridigliozzi interviews Dr. Pejman Katiraei about a novel "backdoor" mechanism through which inhaled fungal toxins may reach the gut through the bloodstream, disrupt the microbiome, increase intestinal permeability, and contribute to persistent symptoms such as bloating, food reactions, fatigue, brain fog, and anxiety.

They also discuss how to identify possible fungal or environmental triggers and the practical steps that may help restore gut health and reduce symptoms.

✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

➡️ Learn more about Dr. Pejman Katiraei:

https://drkatiraei.com/

https://wholistickids.com/

https://www.instagram.com/wholistickids/

We Tested Our Home and We Don't Have Mold! https://www.youtube.com/watch?v=lcdjPSD5QDo

Mold Substack Protocol: https://pkatiraei.substack.com/p/mold-protocol-for-children-with-asd

💊 Featured Products & Supplements

EnviroBiomics Tests: https://www.envirobiomics.com/ref/27392/

Lis Biotech Tests: https://lisbiotech.com/

Hista Digest: https://store.drruscio.com/products/hista-digest-capsules?variant=4217464743546

Mirica: https://www.amazon.com/gp/product/B07365MZLY/ref=as_li_qf_asin_il_tl?ie=UTF8&tag=hghy-google-ads-20&creative=9325&linkCode=as2&creativeASIN=B07365MZLY&linkId=7bc6f62e0f4e5c01f94c938d05ed7823

ANRC Essentials Plus Capsules 180 ct:

https://www.autism-store.com/products/anrc-essentials-plus-capsules-180-ct?gad_source=1&gad_campaignid=21403744485&gbraid=0AAAAA97GzlK2RDtK29lVrexVnymTqdwVB&gclid=Cj0KCQjwsMLSBhD9ARIsAIpUTDr9cycb71lEU5qWznfBoY1L5_UT4h5NfDHQHm29X5E8zLo3gk8S-scaAhPJEALw_wcB

NeuroNeeds Energy Needs: https://www.neuroneeds.com/product/energyneeds/

👇 Watch more videos like this 👇

➡️ How to Tell If You Have Mold in Your Home (And What To Do Next): https://www.youtube.com/watch?v=utLr0rQghfs

➡️ Fungus – The Hidden Reason Symptoms Keep Coming Back: https://www.youtube.com/watch?v=lIb2DXdInv4

➡️ Mold Exposure Story: Healing Cordila's Fatigue, Weight Gain, & Nausea: https://www.youtube.com/watch?v=zdVGK5J2Skg

➡️ Top Treatments To Detox Mold Exposure and Mycotoxins For Good:

https://www.youtube.com/watch?v=KSLtfGRNPKI

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇Read these next 👇

➡️ Mold Detox Diet: Foods that May Support Recovery:

https://drruscio.com/mold-detox-diet/

➡️ Black Mold Symptoms: What's Real, What's Not, and What to Do:

https://drruscio.com/black-mold-symptoms/

➡️ Are Your Seasonal Allergies Actually An Allergy to Mold?:

https://drruscio.com/allergy-to-mold/

00:00 Intro

03:36 Hidden Effects of Fungus & Mold

07:15 Surprising Fungus & Mold Facts

11:44 Signs of Mold Exposure

17:21 MCAS & Nervous System Signs

18:33 Gut Symptoms

22:31 How It Triggers Leaky Gut

42:29 Gut-Brain Effects & Inflammation

50:17 Sinus Problems

52:54 Neurodegenerative Disease Connection

54:28 Best Mold Tests

01:28:25 Mold Diagnostic Framework

01:31:31 Dr. Katiraei's Protocol

01:37:57 Mitochondria Supplements

01:38:56 Gut & Antifungal treatments

01:45:50 Key Takeaways

📉 Dysmotility and proton pump inhibitor use are independent risk factors for small intestinal bacterial and/or fungal overgrowth: https://pubmed.ncbi.nlm.nih.gov/23574267/

📉 Gut-Brain Inflammation and Disrupted Homeostasis Due to Activation of Mast Cells and Microglia:

https://pubmed.ncbi.nlm.nih.gov/41751904/

📉 Mycotoxin Deoxynivalenol Has Different Impacts on Intestinal Barrier and Stem Cells by Its Route of Exposure: https://pubmed.ncbi.nlm.nih.gov/32987679/

📉 Chronic rhinosinusitis and cognition: https://pubmed.ncbi.nlm.nih.gov/40619980/

📉 A positive correlation between autonomic nervous system function and endoscopic disease severity in chronic rhinosinusitis: https://pubmed.ncbi.nlm.nih.gov/40988571/

Facebook - https://www.facebook.com/DrRuscio

Instagram - https://www.instagram.com/drruscio/

DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.

https://drkatiraei.com/

https://wholistickids.com/

https://www.instagram.com/wholistickids/

We Tested Our Home and We Don't Have Mold! https://www.youtube.com/watch?v=lcdjPSD5QDo

Mold Substack Protocol: https://pkatiraei.substack.com/p/mold-protocol-for-children-with-asd

SIBO & Parasite Antimicrobial Protocol: https://drruscio.com/biofilm-protocol/?nab=0&utm_source=youtube

Elemental Diet: https://store.drruscio.com/pages/elementalheal

Triple Therapy Probiotics: https://store.drruscio.com/products/triple-therapy-probiotic

Gut Rebuild Nutrients: https://store.drruscio.com/products/gut-rebuild-nutrients-powder-chocolate?srsltid=AfmBOopnMhnrTlDklAWPUIyuoOFwM3FwTahLXX4888KzfgBc-Ym9bUvt

Parasites are an often-overlooked factor in chronic gut symptoms, food intolerance, histamine-type reactions, fatigue, and cases where patients feel stuck despite addressing SIBO, Candida, or other common gut imbalances. In this episode, Dr. Ruscio, Dr. Jake Vonfeldt, and Dr. Scott Spiridigliozzi discuss common parasites like Giardia, Cryptosporidium, Blastocystis, pinworms, and helminths, why standard testing can miss them, and how clinical history can help determine when parasites deserve closer consideration. They also share both natural and pharmaceutical parasite protocols, along with practical guidance on when each approach may be appropriate.

✅Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

📖Healthy Gut Healthy You Book by Dr. Michael Ruscio: https://store.drruscio.com/products/healthy-gut-healthy-you

👇 Watch more videos like this 👇

➡️Expert Reveals Signs You Have Parasites (And How to Treat):

https://www.youtube.com/watch?v=EiiGdORqOek

➡️Cure SIBO FASTER (New Research):

https://youtu.be/u8MsOY5rgAU?si=Bvi5qBXv_NeNO_-l

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇Read these next 👇

➡️ Protozoan Parasites: What They Mean and How to Treat Them:

https://drruscio.com/protozoan-parasite/

➡️SIBO Biofilm Explained: Symptoms, Causes, and a Treatment Protocol:

https://drruscio.com/sibo-biofilm/

00:00 Intro

02:26 About Dr. Vonfeldt & Dr. Spiridigliozzi

06:04 Common Parasites, Sources & Key Symptoms

18:59 Prevalence & challenges

25:59 Testing

43:05 Treatment

01:07:38 Natural Protocol

01:19:36 Pharmaceutical Protocol

01:36:56 Cases

01:43:31 Chronic symptom recovery map

01:48:08 Key insights

📉Intestinal parasitism in the United States: update on a continuing problem:

https://pubmed.ncbi.nlm.nih.gov/8024063/

📉Perceived food intolerance and irritable bowel syndrome in a population 3 years after a giardiasis-outbreak: https://pubmed.ncbi.nlm.nih.gov/26585714/

📉Irritable bowel syndrome and chronic fatigue 6 years after giardia infection:

https://pubmed.ncbi.nlm.nih.gov/25115874/

📉Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth: https://pubmed.ncbi.nlm.nih.gov/41394228/

📉Blastocystis, urticaria, and skin disorders: https://pubmed.ncbi.nlm.nih.gov/31873864/

📉Urticaria by Blastocystis hominis. Successful treatment with paromomycin: https://pubmed.ncbi.nlm.nih.gov/8237719/

📉An atypical urticaria case caused by Giardia intestinalis: https://pubmed.ncbi.nlm.nih.gov/36449653/

📉The Landscape of Parasitic Infections in the United States: https://www.modernpathology.org/article/S0893-3952(23)00122-9/fulltext

📉Utility of multiple-stool-specimen ova and parasite examinations in a high-prevalence setting:

https://pubmed.ncbi.nlm.nih.gov/10405376/

📉Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth: https://pubmed.ncbi.nlm.nih.gov/41394228/

📉The effectiveness of empirical anti-parasitic treatment in returning travellers with persistent abdominal symptoms: https://pubmed.ncbi.nlm.nih.gov/29232458/

📉Albendazole Treatment Improves Work Capacity in Women Smallholder Farmers Infected with Hookworm:

https://pmc.ncbi.nlm.nih.gov/articles/PMC5953358/

📉Saccharomyces boulardii and infection due to Giardia lamblia: https://pubmed.ncbi.nlm.nih.gov/16798698/

📉Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystis hominis infection: https://pubmed.ncbi.nlm.nih.gov/20922415/

📉N-acetylcysteine and intestinal health: a focus on its mechanism of action: https://pubmed.ncbi.nlm.nih.gov/25553484/

📉Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome: https://pubmed.ncbi.nlm.nih.gov/30108163/

📉Effects of vitamin A supplementation on intestinal barrier function, growth, total parasitic, and specific Giardia spp infections in Brazilian children: https://pubmed.ncbi.nlm.nih.gov/20038852/

📉Impact of vitamin A on selected gastrointestinal pathogen infections and associated diarrheal episodes among children in Mexico City, Mexico: https://pubmed.ncbi.nlm.nih.gov/17041847/

📉Prevalence, Risk Factors, and Outcomes of Irritable Bowel Syndrome After Infectious Enteritis:

https://pubmed.ncbi.nlm.nih.gov/28069350/

📉Use of berberine in treatment of giardiasis: https://pubmed.ncbi.nlm.nih.gov/1096596/

📉Inhibition of enteric parasites by emulsified oil of oregano in vivo: https://pubmed.ncbi.nlm.nih.gov/10815019/

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DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.

In this episode, Dr. Ruscio breaks down the surprising gut and systemic benefits of NAC (N-acetylcysteine), including how it may help break down biofilms, support SIBO and H. pylori treatment, improve gut lining repair, boost nutrient absorption, and support glutathione, mitochondria, and brain health. You'll also learn when sustained-release NAC may be useful, how to dose NAC properly, and what side effects or cautions to keep in mind.

✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

💊 Featured Products:

Biota Dissolve: https://store.drruscio.com/products/biota-dissolve

Jarrow Formulas N-A-C Sustain 600 mg: https://www.amazon.com/Jarrow-Formulas-Sustain-Supports-Function/dp/B0013OVVK0/

👇 Watch more videos like this 👇

➡️ Cure SIBO FASTER (New Research):

https://www.youtube.com/watch?v=u8MsOY5rgAU

➡️ 5 Reasons You Need Glutathione & How To Boost It:

https://www.youtube.com/watch?v=7k7YT70MnA4

➡️ 8 Ways to Beat Brain Fog & Boost Your Cognition:

https://www.youtube.com/watch?v=Tk_ICGk0RwQ

➡️ Butyrate – The SIBO Treatment Nobody Talks About:

https://www.youtube.com/watch?v=5B4l1yOn9UA

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇 Read these next 👇

➡️ SIBO Biofilm Explained: Symptoms, Causes, and a Treatment Protocol:

https://drruscio.com/sibo-biofilm/

➡️ What are Biofilms?: https://drruscio.com/biofilms/

➡️ The Best Glutathione Foods (and When to Supplement):

https://drruscio.com/glutathione-foods/

➡️ 8 Best Microbiome Supplements for a Happier, Healthier Gut:

https://drruscio.com/best-microbiome-supplements/

00:00 What is NAC?

01:47 H. pylori

04:50 SIBO & biofilms

11:00 Gut lining & nutrient absorption

15:22 IBD

18:18 Systemic benefits

24:16 Gut health protocol

26:14 Systemic protocol

27:29 Side effects

Supplementary endoscopy video reproduced from: Baumgartner M, Lang M, Holley H, et al. Mucosal Biofilms Are an Endoscopic Feature of Irritable Bowel Syndrome and Ulcerative Colitis. Gastroenterology (2021). Available on PubMed Central. Licensed under CC BY 4.0.

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC8527885/

License: https://creativecommons.org/licenses/by/4.0/

Changes: trimmed

📉 N-acetylcysteine and intestinal health: https://pubmed.ncbi.nlm.nih.gov/25553484/

📉 Biofilm demolition and antibiotic treatment to eradicate resistant Helicobacter pylori:

https://pubmed.ncbi.nlm.nih.gov/20478402/

📉 N-acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication: https://pubmed.ncbi.nlm.nih.gov/30746681/

📉 N-acetylcysteine as powerful molecule to destroy bacterial biofilms:

https://pubmed.ncbi.nlm.nih.gov/25339490/

📉 Mucosal Biofilms Are an Endoscopic Feature of Irritable Bowel Syndrome and Ulcerative Colitis:

https://pubmed.ncbi.nlm.nih.gov/34146566/

📉 Low dose rifaximin combined with N-acetylcysteine is superior to rifaximin alone in a rat model of IBS-D:

https://pubmed.ncbi.nlm.nih.gov/39103611/

📉 Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth: https://pubmed.ncbi.nlm.nih.gov/41394228/

📉 Effect of N-acetylcysteine on remission maintenance in patients with ulcerative colitis: https://pubmed.ncbi.nlm.nih.gov/33067169/

📉 Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: https://pubmed.ncbi.nlm.nih.gov/33783984/

📉 N-Acetylcysteine Supplementation Elevates Human Brain Glutathione In Vivo: https://cds.ismrm.org/protected/17MProceedings/PDFfiles/4553.html?utm_

📉 Treatment effects of N-acetyl cysteine on resting-state functional MRI and cognitive performance in patients with chronic mild traumatic brain injury: https://pubmed.ncbi.nlm.nih.gov/38299014/

📉 Clinical trials of N-acetylcysteine in psychiatry and neurology: https://pubmed.ncbi.nlm.nih.gov/25957927/

📉 Influence of N-Acetylcysteine Supplementation on Physical Performance and Laboratory Biomarkers in Adult Males: https://pubmed.ncbi.nlm.nih.gov/37299425/

📉 COVID-19 clinical outcomes and N-acetylcysteine (CoViNAC study): https://pubmed.ncbi.nlm.nih.gov/40418545/

📉 Sinus Irrigation with N-Acetylcysteine after Endoscopic Sinus Surgery for Chronic Rhinosinusitis:https://pubmed.ncbi.nlm.nih.gov/39125554/

📉 The effects of N-acetylcysteine supplement on metabolic parameters in women with polycystic ovary syndrome: https://pubmed.ncbi.nlm.nih.gov/37841396/

📉 The role of N-acetyl-cysteine (NAC) orally daily on the sperm parameters and serum hormones in idiopathic infertile men: https://pubmed.ncbi.nlm.nih.gov/33405232/

📉 Anti-Inflammatory and Anti-Oxidant Properties of N-Acetylcysteine:https://pubmed.ncbi.nlm.nih.gov/39064168/

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Instagram - https://www.instagram.com/drruscio/

DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.

New research suggests that low-dose peptide therapy may help calm histamine-driven inflammation and mast cell activation in people with stubborn symptoms like food reactions, brain fog, fatigue, flushing, itching, hives, bloating, and digestive distress. In this episode, Dr. Ruscio explains how the gut, histamine, and mast cells are connected, what the latest human research shows, and why this approach may help some patients who haven't fully responded to diets, supplements, or other natural therapies.

📉 Utility of glucagon-like-peptide-1-receptor agonists in mast cell activation syndrome: https://pubmed.ncbi.nlm.nih.gov/40675372/

✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

📖 Free Guides

Histamine Intolerance: https://drruscio.com/guides/get-histamine-intolerance-guide/

MCAS Questionnaire: https://drruscio.com/guides/get-mcas-symptom-questionnaire/

💊 Featured Products

https://koramd.com/products/personalized-glp-1-treatments

👇 Watch more videos like this 👇

➡️ 4-Step Protocol to Treat Histamine Intolerance (Best Diet & Supplements):

https://www.youtube.com/watch?v=9Da_Dar8Cjo

➡️ The Best And Worst Foods For Histamine Intolerance:

https://www.youtube.com/watch?v=hird4u7tHis

➡️ SIBO, Histamine & the Vagus Nerve:

https://www.youtube.com/watch?v=V2IeX9qRZzE

➡️ The Top Anti-Inflammatory Foods You Should Eat Every Day:

https://www.youtube.com/watch?v=NF5gOX-VsFY

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇 Read these next 👇

➡️ Everything You Need To Know About Histamine Intolerance:

https://drruscio.com/everything-you-need-to-know-about-histamine-intolerance/

➡️ Can I Take Quercetin for Histamine Intolerance?:

https://drruscio.com/quercetin-for-histamine-intolerance/

➡️ GLP-1 Benefits Beyond Weight Loss: IBS, PCOS, and Risks:

https://drruscio.com/glp-1-benefits/

➡️ Understand Diamine Oxidase & Manage Your Histamine in 5 Steps:

https://drruscio.com/diamine-oxidase/

00:00 89% improved with peptides

02:44 Root causes of histamine intolerance

04:51 How peptides help

07:17 Breakthrough study on peptides & histamine

11:27 Do doctors agree?

14:17 Other supportive data

16:11 Recommended peptide protocol

19:01 Safety & side effects

20:29 Where to source

22:53 Close

📉 Utility of glucagon-like-peptide-1-receptor agonists in mast cell activation syndrome: https://pubmed.ncbi.nlm.nih.gov/40675372/

📉 Concomitant Prevalence of Low Serum Diamine Oxidase Activity and Carbohydrate Malabsorption:

https://pubmed.ncbi.nlm.nih.gov/28042564/

📉 Improvement of Chronic Spontaneous Urticaria After Glucagon-Like Peptide 1 Receptor Agonist Therapy: Report of Two Cases: https://pubmed.ncbi.nlm.nih.gov/41535531/

📉 Unintended Benefit of GLP-1 Treatment for Obesity: Resolution of Chronic Systemic Mastocytosis Symptoms:

https://bariatrictimes.com/glp1-resolution-chronic-systemic-mastocytosis-symptoms/?utm_

📉 Pain relief and pain intensity response to GLP-1 receptor agonist ROSE-010 in irritable bowel syndrome:

https://pubmed.ncbi.nlm.nih.gov/35234561/

📉 Glucagonlike Peptide-1 Receptor Agonists and Asthma Risk in Adolescents With Obesity:

https://pubmed.ncbi.nlm.nih.gov/41632171/

📉 Association of glucagon-like peptide-1 agonist use with atopic dermatitis in obese patients:

https://pubmed.ncbi.nlm.nih.gov/41033491/

📉 Effects of six months treatment with liraglutide among patients with psoriasis and obesity, beyond metabolic control?: https://pubmed.ncbi.nlm.nih.gov/40267547/

📉 International Society for Mast Cell Activation Syndromes:https://ismcas.org/

Facebook - https://www.facebook.com/DrRuscio

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DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.

Free Candida Guide: https://drruscio.com/guides/get-candida-diet-guide/

Free Home Mold Guide: https://drruscio.com/guides/get-home-mold-guide/

Dr. Ruscio and Dr. Scott discuss a clinical framework for fungus, Candida, and mold as potential drivers of persistent gut, sinus, brain fog, fatigue, and inflammatory symptoms. They cover key diagnostic clues, sinus involvement, blood mold antibodies, sinus CT, limitations of urine mycotoxin testing, and treatment options including diet, probiotics, herbals, biofilm support, sinus therapies, and prescription antifungals.

✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

💊 Featured Products

Biofilm Disruptor: https://store.drruscio.com/products/biota-dissolve

Biota Clear 1a (Oregano Oil): https://store.drruscio.com/products/biota-clear-1a

PARI SINUS2: https://www.pari.com/int/products/inhalation-devices/pari-sinus2/

Biofilm Clear-X: https://store.drruscio.com/products/biofilm-clear-x-silver-free-edta-nasal-spray

Xlear Nasal Spray: https://store.drruscio.com/products/xlear-nasal-spray

👇 Watch more videos like this 👇

➡️ Eat These 7 Foods EVERY DAY for SIFO & Candida: https://www.youtube.com/watch?v=KIKgNtxC3Mw

➡️ Get Rid Of Candida & SIFO in 4 Simplified Steps (Works Fast): https://www.youtube.com/watch?v=EenuIwuJ7h0

➡️ Mold Toxicity Symptoms & Solutions: Expert Guide to Testing and Treatment: https://www.youtube.com/watch?v=qolB9bIH7DQ

➡️ How to Tell If You Have Mold in Your Home (And What To Do Next): https://www.youtube.com/watch?v=utLr0rQghfs

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇 Read these next 👇

➡️ A Practitioner-Approved Candida Cleanse That Works: https://drruscio.com/candida-cleanse/

➡️ What Is the Strongest Candida Killer? (Evidence-Based Answer): https://drruscio.com/strongest-candida-killer/

➡️ Black Mold Symptoms: What's Real, What's Not, and What to Do: https://drruscio.com/black-mold-symptoms/

➡️ Mold Detox Diet: Foods that May Support Recovery: https://drruscio.com/mold-detox-diet/

00:00 Fungal treatment problems

03:24 How prevalent is fungus?

05:08 Surprising forms of fungus (mold)

07:49 Why mold & fungus co-occur

09:22 Common mold testing issues

15:50 Mold & fungus symptoms

23:27 Our mold diagnostic framework

27:30 Sinus testing & why it's important

44:54 Best diets

46:24 Natural supplements

47:19 Sinus treatment

01:06:29 Medications

📉 Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth: https://pubmed.ncbi.nlm.nih.gov/41394228/

📉 Dysmotility and proton pump inhibitor use are independent risk factors for small intestinal bacterial and/or fungal overgrowth: https://pubmed.ncbi.nlm.nih.gov/23574267/

📉 The diagnosis and incidence of allergic fungal sinusitis: https://pubmed.ncbi.nlm.nih.gov/10488788/

📉 Case Study: Rapid Complete Recovery From An Autism Spectrum Disorder After Treatment of Aspergillus With The Antifungal Drugs Itraconazole And Sporanox: https://pubmed.ncbi.nlm.nih.gov/33132781/

📉 Efficacy of generic forms of itraconazole capsule in treating subjects with chronic pulmonary aspergillosis:

https://pubmed.ncbi.nlm.nih.gov/36967117/

Facebook - https://www.facebook.com/DrRuscio

Instagram - https://www.instagram.com/drruscio/

DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.