Today, I'm joined by the brilliant Dr. Elena Gross, a neuroscientist with an inspiring story and a relentless drive to solve the mysteries behind chronic migraines and brain health. Dr. Gross's personal journey—enduring twenty days of migraine each month and navigating countless failed treatments—led her from crawling through the pain to founding Brain Ritual, a company reimagining brain fuel for longevity.

Episode Timestamps:

Intro and offers ... 00:00:00

Elena Gross's journey from chronic migraines to neuroscience ... 00:46

Distinguishing migraines from headaches ... 08:13

Energy deficit in the brain and ketones as a solution ... 15:05

Mechanisms and benefits of ketones for brain health ... 23:03

Micronutrients and mitochondrial support ... 28:20

Perfume, toxins, and migraine triggers ... 32:30

Hormonal, dietary, and oxidative stress factors in migraines ... 34:33

Exogenous ketones: Types, safety, and application ... 44:43

Brain Ritual supplement overview ... 47:04

Expanding beyond migraines: Mitochondria and neuropsychiatric health ... 57:31

Four pillars for mastering migraines ... 67:00

Actionable starting step for listeners ... 71:58

How to access Brain Ritual and community ... 73:10

Our Amazing Sponsors:

Regenerive - Most cheap Ashwagandha is bulked up with stems and leaves to inflate the "actives." Those parts can bring compounds you don't actually want in your body. A root-only extract containing four newly identified bioactives, the ASHX4 Complex. Visit regenerive.co and use code NAT25 for 25% off.

StemRegen - A plant-based supplement protocol designed to enhance stem cell function. support your recovery, flexibility, and long-term vitality. Visit stemregen.co/NAT15 and use code: NAT15 for 15% off your order.

Blue Peptide Spray from Young Goose - brings the message back loud and clear. With NAD+ APEX to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.

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Today, I'm sharing my go-to biohacking strategies and supplement stacks for leveling up your health and longevity. After years of testing the latest tech and science-backed interventions, I've curated smart bundles for better sleep, sharper focus, and lasting energy—perfect for your own routine or thoughtful holiday gifting.

We'll cover why each pick works, from essentials like magnesium and Urolithin A to recovery devices and productivity tools. You'll also get the inside scoop on practical ways to personalize your approach and make smart choices during seasonal sales.

If you're looking to supercharge your well-being or help someone you love feel their best, this episode is your actionable guide to vitality, clarity, and thriving all season long.

Go To NatNiddam.com/giftguide for all the holiday deals!

Episode Timestamps:

Intro and offers ... 00:00:00

Sleep and recovery bundles: Trocalm, Troz, magnesium, gadgets ... 05:43

Serenity and Sanity Set for busy moms ... 10:37

Fitness and workout performance bundles ... 13:23

Foodie and longevity nutrition gifts ... 19:13

Nitric oxide and vegetable support ... 21:57

Anti-aging skin and vitality bundles ... 23:06

Golden Glow bundle: Stem Regen, Prodrome, bioregulators ... 25:20

Wellness and immune support bundles ... 29:05

Biohacker and luxury splurge bundles ... 31:16

Focus and home office essentials ... 33:58

Hydrogen, water, and holistic elements ... 40:01

Our Amazing Sponsors:

Nootropept by LVLUP - an advanced cognitive enhancement formula that combines fast-acting neuropeptides, cholinergic support, and mitochondrial-boosting compounds to sharpen mental clarity, memory, and long-term brain performance. Visit https://lvluphealth.com/ and use code NAT at checkout for 20% off.

NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase.Timeline.com/nat20

BerkeleyLife - Two Berkeley Life capsules deliver the dietary nitrates your body needs to support nitric oxide production. When you subscribe at BerkeleyLife.com/NAT, you'll get a free tube of 50 Nitric Oxide test strips with your first delivery.

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Today, I'm joined by the inspiring Dr. Darshan Shah, a board-certified surgeon who made the bold leap from the operating room to the forefront of longevity and functional medicine. In our conversation, Dr. Shah opens up about his own journey through burnout, chronic illness, and autoimmune disease, and shares how simple, consistent lifestyle changes became the real medicine that transformed his health. His experience revealed firsthand just how powerful habits like movement, proper nutrition, and sleep can be—often succeeding where surgery and prescriptions fell short.

Episode Timestamps:

Intro and offers ... 00:00:00

Dr. Darshan Shah's journey from surgery to lifestyle medicine ... 00:04:37

Simple actions: nutrition, movement, habit formation ... 00:08:41

Challenges of doctors embracing lifestyle changes ... 00:11:06

Building a parallel system: prevention and chronic care ... 00:14:32

Empowering patients: tech, wearables, and AI ... 00:18:27

Therapeutic plasma exchange (TPE): mechanism and safety ... 00:27:47

Essential biomarker and at-home tests ... 00:48:19

Continuous glucose monitors and real-time health feedback ... 00:52:33

Next Health model: prevention, functional, lifestyle, longevity ... 00:43:08

Longevity circuit: cellular gym approach ... 00:59:37

Liquid biopsy and early cancer detection ... 01:02:08

Advice for health, self-care, and lifelong vitality ... 01:09:31

Where to learn more and clinic expansion ... 01:10:26

Our Amazing Sponsors:

Manukora honey - From remote forests in New Zealand, where bees collect nectar from the native Manuka tea tree. That nectar is naturally rich in antibacterial compounds like MGO, plus antioxidants and prebiotics that support immunity and gut health. Visit manukora.com/NAT to save up to 31% plus $25 worth of free gifts with the Starter Kit - you'll get an MGO 850+ Manuka Honey jar, 5 travel sticks, a wooden spoon, and a guidebook. *Look out for their Black Friday/Cyber Monday promotion from 11/17/25 - 12/02/25..

Qualia NAD+ - A groundbreaking, doctor-formulated vegan formula that boosts your NAD levels by up to 67% for enhanced cellular energy, DNA repair, and detox support. Go to qualialife.com/NATHALIE and use promo code NATHALIE to get 15% off—and try it risk-free with their 100-day money-back guarantee.

Probiotic Breakthrough by Bioptimizers - uses a stress-tested Lactobacillus plantarum strain that showed over 30× greater survival in bile and intestinal fluid vs. generic strains. Save 15% at bioptimizers.com/bionat and use code BIONAT for 15% off any order.

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Today, I'm joined by the inspiring Rowena Gates, co-founder of ENG3 and the innovative mind behind the NanoVi device—a technology specialized in supporting cellular repair and resilience. Rowena Gates shares her unique journey from teaching high school and academic consulting to pioneering advanced biotech for health optimization. Her story is a powerful reminder of how unlikely paths can lead to groundbreaking innovation in longevity science.

Visit https://eng3corp.com/niddam/ and receive a free pelican carrying case with your order of NanoVi

Episode Timestamps:

Intro and offers ... 00:00:00

Role of reactive oxygen species and NanoVi's mechanism ... 00:07:11

Protein folding, DNA repair, and longevity ... 00:11:00

NanoVi's impact on NAD IV tolerance and stress ... 00:16:07

Ordered water and protein folding explained ... 00:22:10

VO2 max, metabolic efficiency, and biological age ... 00:27:39

Guidelines for NanoVi: Performance, recovery, and hormesis ... 00:34:44

Brain endurance and cognitive recovery ... 00:39:09

Sleep, HRV, and effects on older adults ... 00:43:46

Anecdotes: ED, cardiovascular health, notable users ... 00:46:33

NanoVi at home: Sleep, recovery, workday use ... 00:51:02

Stacking with other modalities (hyperbaric, red light) ... 01:00:05

Vision: Accessibility via shared devices ... 01:02:07

Main message: Body's capacity to repair ... 01:04:40

Our Amazing Sponsors:

Blue Peptide Spray by Young Goose - With NAD+ APEX™️ to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.

BEAM Minerals - Mineral deficiency support. One shot in the morning, tastes like water, and you've just restored every essential mineral your cells are craving. Go to beamminerals.com, use code NAT20, and get 20% off your first order.

NEW Tranq Dart - a multi-pathway sleep support from Wizard Sciences. It's not a knockout pill; it's a gentle nudge toward that wind-down zone. Take 30 minutes before bed, and it helps your body and brain sync up for sleep. Visit wizardsciences.com and use code NAT15 for 15% off.

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Today, let's talk about immune support. With the festive season and colder months upon us, it's the perfect time to focus on practical strategies to help you build a resilient, balanced immune system. I share not only the science-backed basics—like sleep, stress management, and the realities of sugar and alcohol—but also my favorite low-tech tools and innovative supplements for fortifying your body's natural defenses.

Studies Mentioned: https://pubmed.ncbi.nlm.nih.gov/39544655/ https://pmc.ncbi.nlm.nih.gov/articles/PMC9471313/

Supplements Mentioned: XClear Nasal Spray

BeeKeepers Naturals Throat Spray (Bee propolis)

Manukora: Manuka Honey (save up to 31%)

Puori: Terrific Vitamin C Effervescent Tablets includes Zinc, D3, Yerba Matte, Ginseng - use in the am (use code NAT for 20% off)

Troscriptions - TroMMune, TroCalm, TroZZ (use NAT10, and get 10% off your first order)

JustThrive: Spore Biotics (use code NAT20 for 20% off)

LVLUP Health:Ultimate GI Repair (use code NAT at checkout for 20% off)

Healthgevity: ImmunoRESTORE+ (use code LONGEVITY)

Bioregulators: Pineal Gland and Thymus (use code LONGEVITY15 for 15% off )

Episode Timestamps:

Intro and offers ... 00:00:00

Balancing the immune system vs. boosting ... 00:01:32

Risks of an overactive immune response ... 00:02:55

Lifestyle practices for immune health ... 00:03:38

Sleep's role and practical sleep tips ... 00:04:41

Sugar's impact on immunity ... 00:09:05

Alcohol, mocktails, and immune suppression ... 00:15:26

Managing stress for immune support ... 00:18:19

Summary of key lifestyle strategies ... 00:24:36

Exercise: benefits and moderation ... 00:26:26

Top supplements for immune support ... 00:28:59

Propolis, Manuka honey, vitamins and probiotics ... 00:29:34

Bioregulators and peptide support ... 00:38:42

Sauna and light therapy for winter immunity ... 00:40:01

Take action before the holiday season ... 00:42:28

Our Amazing Sponsors:

NootroPept by LVLUP: an advanced cognitive enhancement formula that combines fast-acting neuropeptides, cholinergic support, and mitochondrial-boosting compounds to sharpen mental clarity, memory, and long-term brain performance. Visit https://lvluphealth.com/ and use code NAT at checkout for 20% off.

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Today, I'm joined by Austin Mao, a serial entrepreneur whose personal journey with plant medicine led him from the high-pressure, Instagram-perfect startup world to founding Ceremonia—one of the leading psychedelic organizations in the U.S. In this candid conversation, Austin shares how a transformative psilocybin ceremony unraveled the layers of ego, revealing new depths of presence, embodiment, and emotional healing.

Episode Timestamps:

Austin's first plant medicine ceremony: ego, healing, and memories ... 00:06:28

Uncovering childhood trauma and learning presence ... 00:08:34

Motivations for plant medicine: curiosity, networking, and pride ... 00:13:46

Core lessons: ego, external vs. internal fulfillment ... 00:14:57

Comparing ayahuasca and psilocybin: safety, access, and tradition ... 00:18:27

Facilitator training and role in psychedelic experiences ... 00:24:48

Purging, meaning-making, and emotional release in ceremony ... 00:27:39

Psychedelics and mental health: impact and effectiveness ... 00:31:27

Retreat model: psilocybin first, ayahuasca later ... 00:37:20

The crucial role of integration post-ceremony ... 00:41:00

Ceremonia's offerings: retreats, online integration, and microdosing ... 00:47:59

Our Amazing Sponsors:

Nature's Marvels - Thymus & Pineal BioRegulators - The Thymus Bioregulator helps keep immune response balanced and small human studies in older adults link it with healthier immune markers and fewer seasonal respiratory issues. The Pineal Bioregulator supports your natural melatonin/circadian rhythm—key when schedules and daylight change—so you get the kind of sleep that underpins immune resilience. Head to profound-health.com and use code LONGEVITY15 for 15% off your first order.

BTS2 Sunlamp by Mitolux - When your skin makes vitamin D from UVB light, it also creates natural companion molecules that help your body use it smarter—so you're not just boosting levels, you're activating your biology the way nature intended. Visit mitolux.com/NAT10. You'll receive 10% off! NAT10 will be automatically applied at checkout.

NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase. Timeline.com/nat20

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Today, I'm joined by Dr. Drew Taylor, a trailblazer in regenerative medicine and the innovative force behind Acorn Biolabs. Dr. Taylor's path is anything but ordinary—he went from pitching in professional baseball to pioneering non-invasive ways to collect and preserve the body's most potent cells, all sourced from our hair follicles. His journey is a testament to the power of curiosity, resilience, and the drive to use cutting-edge science for better health and longevity.

ONE-FREE Year of Hair Follicle Banking:

Whether it's for present use or future use, you get one full year of free banking.

All you have to do is find a clinic that offers Acorn near you, sign up for your hair follicle harvest, and then go to acorn.me/nat and use code NAT at checkout to get one free year of banking.

Episode Timestamps:

Dr. Drew Taylor's journey: pro athlete to stem cell science ... 00:06:24

Transition from sports to regenerative medicine ... 00:09:45

Advances in stem cell therapy and cell reprogramming ... 00:11:01

Donor vs. autologous stem cell differences ... 00:12:12

Stem cell hierarchy and pluripotency explained ... 00:19:00

Limits of biological age tests ... 00:23:27

Non-invasive harvesting from hair follicles ... 00:27:36

Advantages of hair follicle cells ... 00:30:10

Age and timing for cell banking ... 00:33:02

Wound healing case study with secretome ... 00:38:19

Secretome, exosomes, and topical treatment potential ... 00:40:43

Hair regrowth and transplant support ... 00:52:12

Accessibility and affordability of Acorn's approach ... 00:56:40

Cryopreservation as a "biological insurance policy" ... 00:59:42

Microneedling and aesthetic results ... 01:00:39

Future uses: sports injuries, immune cells, organ regeneration ... 01:04:30

Final advice for longevity and health span ... 01:13:16

How to access Acorn's services ... 01:15:18

Our Amazing Sponsors:

Puori - Minimally processed, made from pasture-raised cows' milk, and it's tested for over 200 contaminants every single batch. Go to Puori.com/NAT and use code NAT for 20% off— it also applies to subscriptions so you'll get nearly a third off the price.

Kineon - Near-infrared light helps improve circulation, oxygen delivery, and mitochondrial function, which can support focus, recovery, and even overall brain health. Visit kineon.io/NATNIDDAM and get 10% off!

Digestive Bitters by Just Thrive - One capsule before eating helps your body absorb more nutrients, ease digestion, and leave you feeling light instead of weighed down. Head over to Justthrivehealth.com/discount/NAT and use code NAT20 for 20% off.

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Today, I'm thrilled to welcome Dr. Amy Killen, a visionary in hormone optimization and regenerative medicine who is transforming the conversation around women's health and longevity. In this episode, Dr. Killen shares her personal journey—from witnessing her mother's struggle after a hip fracture, to becoming a steadfast advocate for correcting the myths and misinformation that still surround estrogen, progesterone, and testosterone optimization.

Episode Timestamps:

Ferritin, iron, and hormonal health basics ... 00:00:43

Dr. Amy Killen's evolving hormone focus ... 00:04:02

Women's Health Initiative and estrogen myths ... 00:06:31

Importance of hormone optimization vs. stem cells ... 00:10:25

Testosterone for women: symptoms, labs, delivery options ... 00:12:05

Side effects and nuances of testosterone therapy ... 00:14:01

SHBG, free testosterone, and lab variability ... 00:16:38

Libido, PT-141, and the biopsychosocial lens ... 00:21:46

Iron and ferritin: sweet spot and skin implications ... 00:29:16

Hot vs. HRT: definitions and individualization ... 00:34:23

Debunking estrogen and breast cancer myths ... 00:41:30

Aging expectations and finding the right doctor ... 00:43:18

Advice for women by decade—20s, 30s, 40s, etc. ... 00:47:20

Our Amazing Sponsors:

Tro Zzz by Troscriptions - This isn't just melatonin—it's a powerhouse! Oblipair gives you honokiol and agarin to enhance GABA binding, while adenosine and cordycepin boost sleep drive and deep sleep. CBD, CBN, and 5‑HTP round it out. Head to troscriptions.com, use NAT10, and get 10% off your first order.

NMN+G Rx by Wizard Sciences - A scientifically formulated blend of NMN, ginsenosides from Panax ginseng, and apigenin. Together, they enhance mitochondrial function, boost NAD+ levels, and support cellular repair. Go to wizardsciences.com and look for NMN+G. Use code NAT15 at checkout to get 15% off your purchase.

Probiotic Breakthrough by Bioptimizers: uses a stress-tested Lactobacillus plantarum strain that showed over 30× greater survival in bile and intestinal fluid vs. generic strains. Save 15% at bioptimizers.com/bionat and use code BIONAT for 15% off any order.

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Today, I'm joined by the pioneering duo behind Young Goose and two of the earliest voices to bring longevity science into the world of skincare. Amitay comes from the red light therapy space, while Anastasia's background is rooted in cancer research and regenerative medicine—together, their bold thesis is that youthful skin is not just about appearance, it's an energy state.

Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.

Episode Timestamps:

Skin longevity: appearance vs resilience vs long-term health ... 00:06:42

Why topical NAD matters for skin ... 00:14:07

Importance and decline of NAD as we age ... 00:18:26

Why spermidine was added to skincare ... 00:21:00

How spermidine drives autophagy and hydration ... 00:25:43

Spermidine's impact on wrinkles and skin barrier ... 00:29:06

Longevity skincare vs traditional approaches ... 00:31:18

Methylene blue's unique benefits and formulation ... 00:34:04

Methylene blue vs other antioxidants ... 00:36:16

Methylene blue's role in recovery and protection ... 00:46:13

Platelet-derived, quantified exosomes explained ... 00:51:44

How to layer exosomes in your skincare ... 01:01:13

Biggest myths in skin longevity ... 01:02:41

Does topical NAD and spermidine really work? ... 01:08:28

Where to start with Young Goose products ... 01:19:33

Our Amazing Sponsors:

Digestive Bitters by Just Thrive - One capsule before eating helps your body absorb more nutrients, ease digestion, and leave you feeling light instead of weighed down. Head over to Justthrivehealth.com/discount/NAT and use code NAT20 for 20% off.

Puori: It's minimally processed, made from pasture-raised cows' milk, and it's tested for over 200 contaminants every single batch. It's also very Yummy! Go to Puori.com/NAT and use code NAT for 20% off— it also applies to subscriptions so you'll get nearly a third off the price.

Thymus & Pineal BioRegulators by Natures Marvels - Thymus Bioregulator helps keep immune response balanced and small human studies in older adults link it with healthier immune markers and fewer seasonal respiratory issues. Pineal Bioregulator supports your natural melatonin/circadian rhythm so you get the kind of sleep that underpins immune resilience. Head to profound-health.com and use code LONGEVITY15 for 15% off your first order.

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Today, I'm joined by Omid Moghadam, a serial inventor and biotech entrepreneur whose fascination with innovation has led him from the world of imaging and semiconductors to groundbreaking advancements in cancer screening. Omid shares how personal experiences—including his mother's battle with cancer and his own early diagnosis—sparked his relentless drive to build better tools for early cancer detection.

Visit https://auria.care/ and use code NAT20 to save 20% off Auria

Episode Timestamps:

Omid Moghadam's path from tech to biotech ... 00:05:05

Personal cancer stories fueling innovation ... 00:09:58

How tears enable advanced screening for breast cancer ... 00:11:16

Advantages and affordability of tear-based testing ... 00:13:48

AI's role in developing Auria ... 00:16:35

Screening vs. diagnostic—key distinctions ... 00:20:12

Early detection and functional medicine approaches ... 00:27:25

Challenges with current breast cancer screening ... 00:39:15

Future directions: more cancer screens and radiopharmaceuticals ... 00:48:31

Accessing Auria and company discount ... 01:01:16

Our Amazing Sponsors:

NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase.

Qualia Senolytic - A cutting-edge formula designed to help your body eliminate senescent cells, also known as "zombie cells." Go to qualialife.com/NATHALIE and use promo code NATHALIE to get 15% off—and try it risk-free with their 100-day money-back guarantee.

Manukora honey - From remote forests in New Zealand, where bees collect nectar from the native Manuka tea tree. That nectar is naturally rich in antibacterial compounds like MGO, plus antioxidants and prebiotics that support immunity and gut health. Visit manukora.com/NAT to save up to 31% plus $25 worth of free gifts with the Starter Kit - you'll get an MGO 850+ Manuka Honey jar, 5 travel sticks, a wooden spoon, and a guidebook.

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