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Use the timestamps below to jump to the peptide topic you care most about!

⸻

Timestamps

0:00 – Introduction
2:22 – Nicotine for Autoimmune Health, Energy & Focus
4:46 – Peptides for Heart Disease and Heart Attack Recovery
6:04 – Rapamycin and Fasting for Longevity
7:14 – Stacking AOD, Tesofensine, and Retatrutide for Fat Loss Plateaus
8:27 – Tesofensine Cycling and New Blends
9:28 – Growth Hormone vs. GH Secretagogues for Women
10:26 – Thyreogen Dosing Protocols
11:19 – Testosterone Start-Up Side Effects & Immune Shifts
12:55 – Regaining Muscle After GLP-1 Peptide Use
13:36 – Mitochondrial Peptides (SS-31) and Fatigue
14:49 – Melanotan 1 Startup Dosing & Tanning Tips
16:20 – Protein Intake for Fat Loss & Muscle Building
16:45 – Peptides for Autoimmunity (Lupus/Hashimoto’s) & Allergy Support
19:23 – Metformin for “Natty” Lifters?
20:54 – Microdosing GLP-1s for Long-Term Metabolic Health
23:11 – Peptides for Elderly, Heart Bypass, and COPD
23:49 – Recovery from Rhabdo, Overactive Bladder, and Aesthetic Injections
26:33 – DADA, Metformin, & Exercise Performance
27:23 – Peptides for Prostate Health & BPH
27:41 – Healing Old Injuries: The Wolverine Stack 3.0
28:12 – Weaning Off Antidepressants with Peptides
28:53 – Oral Testosterone (Kyzatrex) vs. Injectables: My Honest Take
32:23 – DMAA, Clenbuterol, and Safer Fat Burners
33:04 – Women on TRT: How to Avoid Voice Changes
34:17 – Carnitine Injection Dosing 101
35:01 – Fasting, Protein, and the Sugar Diet
36:03 – Peptides for Chronic Lung Disease & My Father-in-Law’s Story
37:15 – Taurine for Heart Rate & Fat Loss
39:11 – “Dumpster Fire Stack” for Extreme Fat Loss
40:12 – BAM15 Dosing and Human vs. Mouse Studies
41:43 – Setmelanotide, Appetite Suppression, and Brutal Nausea
44:14 – Peptides for Back Pain & Degenerative Discs
45:28 – PCOS & Peptides for Women
46:04 – Peptide Pens, Needle Sizes, and Injection Tips
47:02 – Nerve Regeneration & Bell’s Palsy
48:05 – Lyme Disease, Fasting, and GLP-1s
50:34 – When to Test Teens for Testosterone & Safe Peptides
51:05 – Peptides for PSA/Prostate, Water Retention, and Women’s Health
53:29 – Jardiance, Preworkout Injections, and Cycling Peptides
54:29 – Peptides for Tendon Injuries
55:06 – Depression, Dopamine Deficiency & Brain Rebuilding Stacks
56:15 – Bang-for-Buck Peptide Stacks for TRT Users
56:50 – Site-Specific Injections for Healing
57:32 – Peptide Longevity After Reconstitution
57:54 – Bioregulator Pills vs. Injections
58:05 – Peptide Safety After Prostate Cancer
59:08 – Menopause, Hormones, and The #1 Thing Women Need
1:00:21 – Clomiphene & HCG on TRT
1:01:30 – Cycling GLP-1s and Cagri
1:02:40 – Final Thoughts, Gratitude, and How to Submit Questions

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Vilon Peptide: The Secret Weapon for Immune Balance, Longevity, and Recovery

0:00 - Introduction & What is Vilon?
0:40 - How Vilon Feels: My Personal Experience
1:35 - Use Cases: Longevity, Pain, Autoimmune, and More
2:32 - What is Vilon? Thymic Bioregulator Explained
3:04 - History: Soviet Origins and Development
4:37 - Unique Properties: Small Structure, Immune Regulation
5:31 - Immune Modulation: How Vilon Restores Balance
6:00 - Mechanisms: Calcium, T-Cells, Cytokines, and More
7:05 - Epigenetic Rejuvenation: Turning Back the Clock
8:23 - Pathways Activated by Vilon
9:13 - Immune System Restoration: Data in Aging and Disease
10:29 - Longevity Effects: Lifespan, Tumor Reduction, Activity
11:22 - Anti-Cancer Properties
12:21 - Tissue Regeneration, Recovery, and Healing
13:22 - Inflammation Modulation: From Gut to Surgery
14:20 - Improved Metabolic and Organ Function
15:28 - Organ Specific Benefits: Heart, Kidneys, and More
15:45 - Nootropic and Brain Health Potential
16:22 - Safety Profile: Side Effects, Tolerance, and Risks
18:20 - Dosing: Animal and Human Protocols
19:55 - Cycling Protocols for Longevity
21:18 - High Dose Protocols: What Science and Experience Show
21:32 - Routes of Administration (SubQ, IM, Oral, Nasal)
22:50 - Study Review: Tumor, Lifespan, Recovery, Immunity
24:22 - Human Trials: Diabetes, Wound Healing, Immunity
25:13 - Potency vs. Other Peptides
25:32 - Synergistic Stacks: Epitalon, Thymalin, SS-31, and More
27:53 - Conclusion: Summary and Who Should Try Vilon
29:06 - Practical Results: Inflammation, Gut, Recovery
29:32 - Use Cases: Health, Longevity, Recovery
30:09 - Mission: Making Peptides Accessible for All

⸻

In this deep dive, I reveal everything you need to know about the vilon peptide—one of the most underappreciated and potent thymic bioregulators. Discover its Soviet research origins, molecular mechanisms, immune balancing, longevity effects, anti-cancer data, healing powers, nootropic potential, and protocols for real-world use. I break down published studies, my experience, and stacking strategies with other powerful peptides like Epitalon and SS-31. Whether you’re fighting chronic inflammation, seeking to reverse biological aging, or wanting optimal recovery and resilience, this video gives you the latest science and my personal tips for dosing, cycling, and maximizing results.

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Are you struggling to lose 50+ pounds and feel like nothing works? In this video, I break down the ultimate “Dumpster Fire” peptide stack for fat loss—a protocol I’ve personally used to help people finally transform their bodies. Whether you’re new to peptides or have tried everything, you’ll learn why this comprehensive approach works where diets and supplements have failed.

Timestamps:

0:00 - Introduction: The Dumpster Fire Stack & Who This Is For
4:01 - The #1 Peptide for Fat Loss: Retatrutide (GLP-1, GIP, Glucagon Agonist)
10:38 - Growth Hormone Support: Tesamorelin, CJC/Ipamorelin, HGH
14:50 - The Mitochondrial Fat Loss Trifecta: MOTS-c, SS-31, SLU-PP-332
22:19 - BAM15 & The Synergy of Stacking for Maximum Results
24:41 - NAD+ & 5-Amino-1MQ: The Fat Loss “Gas Pedal”
27:40 - Glutathione for Detox & Liver Health During Rapid Weight Loss
29:58 - Why This Stack Works: Synergy, Pathways, and Muscle Preservation
34:10 - Dosing Chart & How to Build Your Protocol
36:05 - Final Thoughts: Who Should (and Shouldn’t) Do This, Plus Real-World Results
37:44 - Gratitude & Community: Join the Movement.

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Curious about the pros, cons, and real-world protocols for using human growth hormone (HGH) and growth hormone peptides together? In this video, I share my personal experience, the science, and practical cycling strategies for optimizing results—whether your goal is fat loss, muscle growth, or longevity.

Timestamps

0:00 – Introduction & Why I’m Updating This Topic
1:00 – My Core Belief: HGH Is the Gold Standard (But Peptides Have a Place)
1:42 – What Are Growth Hormone Peptides? GHRPs vs GHRHs Explained
2:20 – HGH vs Peptides: The Core Difference
2:58 – Why Use HGH? My Personal Experience and When It’s Best
3:53 – How Exogenous HGH Works (and the Pituitary Shutdown Question)
4:53 – Peptide Types: GHRH vs GHRP (and Why It Matters)
5:28 – The Science of Peptide Synergy: Why Combine Peptides?
7:19 – What Happens When You Stack Peptides (CJC+Ipamorelin)
8:02 – Key Benefits: Lean Muscle, Fat Loss, Recovery, and More
9:04 – Fat Loss: How HGH and Peptides Each Work
10:37 – Recovery, Sleep, Skin, and Cognitive Benefits
12:11 – Metabolic and Cardiovascular Benefits
13:01 – Comparing HGH and Peptides Head-to-Head
14:33 – Risks: Side Effects of HGH vs Peptides
15:58 – Accessibility, Cost, and Dosing Frequency
16:56 – My Favorite Protocols: How I Cycle HGH and Peptides
17:31 – How to Alternate and Combine for Maximum Effect
18:19 – Pulsatile Therapy, Circadian Rhythm, and Optimizing Results
19:11 – Example Yearly Cycle: How I Use HGH and Peptides Throughout the Year
20:49 – Why You Need to Experiment for Yourself (Personalization is Key)
22:02 – Final Thoughts, Gratitude, and How to Ask Me Questions

What you’ll learn in this video:
 • The real science and mechanism behind HGH and growth hormone peptides
 • My honest protocol for stacking and cycling both for best results
 • When to use just peptides, just HGH, or both together
 • How to avoid side effects and get the best from your regimen
 • My seasonal “real-life” cycling strategy for year-round progress

Want the full peptide cheat sheet and exclusive protocols? Check the link below. And join our Fully Optimized Health community to nerd out with 700+ other biohackers.

Drop your questions in the comments—I read them all!

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Are you thinking about switching from tirzepatide to retatrutide? In this video, I’ll walk you through everything you need to know about making the transition—from the science and mechanisms, to real-world dosing strategies and the side effect differences I see in my community. If you’re looking for maximum fat loss and the most up-to-date peptide protocols, this video is for you.

Timestamps

0:00 – Introduction: Why the switch from tirzepatide to retatrutide is happening
0:45 – Clinical background: Compounding issues and the rising popularity of retatrutide
1:30 – My transition philosophy: Gradual tapering and best practices
2:04 – Mechanisms: How tirzepatide and retatrutide work in the body
3:10 – Tirzepatide: GIP and GLP-1 agonism explained
3:54 – Why tirzepatide has fewer side effects vs semaglutide
4:01 – Retatrutide: What does triple agonism mean?
4:42 – Metabolic advantages: Glucagon receptor activation, liver fat reduction, energy expenditure
5:45 – Head-to-head comparison: Why retatrutide is stronger for fat loss
6:51 – Dose escalation: How to titrate both drugs (side effects & protocol)
7:56 – Study outcomes: Average weight loss on both drugs
9:10 – A1C improvements: Comparing metabolic health markers
10:00 – Retatrutide’s liver benefits and impact on longevity
11:02 – What to expect when you switch: Side effects, hunger, and adaptation
12:02 – Appetite differences: Why tirzepatide suppresses appetite more at equal doses
13:30 – Side effect management: GI symptoms, heart rate, and tips
14:02 – My detailed titration schedule for switching safely
16:50 – Can you mix tirzepatide and retatrutide?
17:39 – Why minimum effective dosing matters and other fat loss pathways
18:01 – Final thoughts: Community support, feedback, and closing

In this video you’ll learn:
 • The step-by-step protocol to taper down tirzepatide and introduce retatrutide safely
 • Key differences in mechanisms (GIP/GLP-1 vs GIP/GLP-1/Glucagon)
 • Real world data on weight loss, A1C, and fatty liver reduction
 • My honest recommendations for side effect management
 • How to listen to your body and titrate up for maximum effect
 • Answers to common questions: can you combine both, and is the switch right for you?

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Are you struggling to balance estrogen while on testosterone? In this video, I break down the surprising connection between metformin and estrogen, why blocking estrogen is NOT the answer, and how metformin may be the healthiest aromatase inhibitor nobody talks about.

0:00 - Introduction: Why Metformin vs Estrogen?
0:45 - The Real Cause of High Estrogen in Men
1:48 - My Experience: High Testosterone, No Estrogen Problems
2:57 - Why Metformin May Beat Aromatase Inhibitors
4:36 - Disclaimer & Perspective
5:00 - Understanding Aromatase in Fat Tissue
6:06 - Obesity, Aromatase, and Hormones
9:06 - Metformin’s Effect on Aromatase: What Science Says
11:12 - Metformin: Selective Estrogen Control in Fat
13:11 - Beyond Fat: Metformin in Ovaries & Lungs
15:57 - How Metformin Modulates Aromatase (Molecular Pathways)
17:46 - Metformin, Insulin, and Aromatase: The Hidden Link
19:05 - Metformin’s Anti-Inflammatory Impact on Estrogen
20:42 - The Power of Reducing Visceral Fat with Metformin
22:45 - Metformin’s Crosstalk with Estrogen Receptors
23:47 - Consequences of Altered Aromatase Activity
25:08 - PCOS, Reproduction, and Metformin’s Role
26:57 - Metformin, Estrogen, and Metabolic Health
28:29 - Summing Up: Metformin as an Estrogen Modulator
29:08 - Walking the Estrogen Tightrope: Real World Takeaways
31:18 - Case Studies & Community Discussion
32:36 - Thank You & Final Thoughts

In this deep-dive, I explain why most men don’t have an “estrogen problem”—they have a visceral fat problem. More fat means more aromatase, which means more testosterone gets converted into estrogen.
I share my experience taking high doses of testosterone (up to 750 mg/week!) with no high-estrogen symptoms, because I keep visceral fat low.

You’ll learn why metformin can act as a natural aromatase modulator, helping to manage estrogen not by blocking it, but by fixing the upstream problems: insulin resistance, inflammation, and excess body fat.

I break down the science, studies, and mechanisms: from AMPK activation, to anti-inflammatory effects, to tissue-specific aromatase control in fat, ovaries, and lungs.

We’ll cover what the research says about metformin lowering estrogen only when it’s pathologically high (like in obesity, PCOS, or inflammation) while keeping healthy estrogen levels intact.

If you’re using testosterone, battling estrogen issues, or worried about aromatase inhibitors’ side effects, this video will show you a healthier, smarter way forward—backed by science and my own clinical experience.

Let me know in the comments if you’ve tried replacing your AI with metformin, or if you’re curious to experiment!

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Are you struggling with chronic fatigue, brain fog, or mysterious autoimmune symptoms? Mold toxicity is one of the most underdiagnosed yet widespread health issues today—and most people don’t even realize it’s the real cause behind their suffering. In this in-depth video, I, Hunter Williams, break down my ultimate peptide stack for mold toxicity, explaining exactly how each peptide works, the clinical evidence, recommended dosages, and how you can use these strategies to reclaim your health.

Timestamps
0:00 – Introduction: Why Mold Toxicity Is So Prevalent  
1:02 – How to Test for Mold Exposure & My North Carolina Story  
3:33 – What Peptides Help with Mold? Full Stack Overview  
4:22 – LL-37: The Antimicrobial Powerhouse  
8:32 – SS-31: The Mitochondrial Repair Peptide  
12:51 – Thymosin Alpha 1 (TA1): Immune Restoration  
17:36 – Thymalin: Bioregulator Peptide for Immune Balance  
22:18 – BPC-157: Regeneration & Gut Healing  
26:31 – TB-500: Repair and Recovery for Mold-Induced Damage  
31:58 – KPV: Anti-Inflammatory & Mast Cell Stabilizer  
37:12 – VIP: The Critical Peptide for True Mold Recovery  
43:16 – Dosage Chart & Protocol (Screenshot This!)  
43:38 – Final Thoughts: Healing Mold Toxicity with Peptides  
44:55 – Mold Toxicity Is More Common Than You Think  
45:17 – Why Most People Don’t Know They Have Mold Issues  
45:22 – Closing & Thank You  

In this video, you’ll learn:
 • The root causes and hidden dangers of mold toxicity
 • How to test for mold exposure (no fluff, just practical steps)
 • Why testosterone optimization matters for mold recovery
 • How each peptide (LL-37, SS-31, TA1, Thymalin, BPC-157, TB-500, KPV, VIP) helps with immune balance, inflammation, and tissue repair
 • Clinical evidence, practical dosing, and real-world application
 • My personal recommendations based on years of research and coaching

Whether you’ve been diagnosed with mold illness, chronic fatigue, CIRS, or you’re just biohacking for better health, this comprehensive guide will walk you through everything you need to know about using peptides to recover from mold exposure.

Screenshot the protocol chart at [43:16] for easy reference!

👇 Share your experience with mold and peptides in the comments below—your story could help someone else heal!

Don’t forget to like, subscribe, and download my free Peptide Cheat Sheet for more advanced protocols.

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In this video, I dive deep into the reasons behind the infamous “GLP plateau”—that frustrating point where fat loss on GLP-1 peptides like semaglutide, tirzepatide, and retatrutide comes to a grinding halt. I break down the physiological, hormonal, and lifestyle factors that drive plateaus, plus practical, science-backed solutions to get results moving again.

⸻

Timestamps

0:00 – Introduction: Why Do GLP-1 Plateaus Happen?
0:35 – Why Weight Loss Plateaus Are Universal
1:22 – How GLP-1s Work (Mechanisms: Semaglutide, Tirzepatide, Retatrutide)
2:36 – Typical Weight Loss Trajectory on GLP-1s
3:18 – When (and Why) Most People Plateau
4:55 – Plateau ≠ Failure: The New Weight Set Point
5:39 – Physiological & Metabolic Causes of Plateaus
6:26 – Resting Metabolic Rate Drop & Adaptive Thermogenesis
7:31 – Decreased Thermogenesis, Exercise Efficiency, & Mitochondria
8:42 – Muscle Loss and Its Impact on Plateaus
9:44 – NEAT (Non-Exercise Activity Thermogenesis) Drops
10:18 – Why the Body Adapts: Our Ancestral Survival Mechanism
11:06 – Hormonal Adaptations: Leptin, Ghrelin, Insulin
13:03 – Leptin Drop: Increased Hunger, Lower Metabolism
13:41 – Ghrelin Rise: Appetite Returns
15:17 – Insulin, Metabolic Health & Fat Loss
17:20 – Thyroid Hormones: T3, Metabolic Rate, and the Plateau
19:03 – Cortisol, Stress, and Fat Storage
20:07 – Sex Hormones: Testosterone, Fat Loss, and Plateaus
21:46 – Amylin, Neuropeptide Y, and Brain Pathways
22:44 – Behavioral & Lifestyle Factors: NEAT, Adherence, Calorie Creep
24:44 – Psychological Fatigue, Sleep, Diet Quality, & Hydration
28:27 – Is It a True Plateau? Body Fat vs. Weight Loss
28:32 – Pharmacological Tolerance & Dosing Issues
30:00 – Appetite Pathways and Receptor Desensitization
31:52 – Dose Ceiling: When More Isn’t Always Better
33:26 – Strategies to Break Through a Plateau
34:16 – Re-evaluating Diet: Macros, Sugar Diet, and Tracking
34:45 – Activity, Resistance Training, and NEAT
35:03 – Sleep, Stress, Thyroid, and Other Medications
35:44 – Add-On Pharmacology: LDN, Cagrilintide, Leptin Analogs
37:01 – Mitochondrial Pathways: BAM15, SLU-PP-332, Carnitine
37:50 – Cycling, Refeeds, and Metabolic Resensitization
39:55 – Fasting, Intermittent Fasting, and Nutrition
40:08 – Recap: Everyone Plateaus—How Will You Respond?
41:02 – Thank You & Outro

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If you’re struggling with fatigue, low motivation, or brain fog while on GLP-1 agonists like tirzepatide or retatrutide, you are NOT alone! I get asked about “GLP-1 fatigue” constantly, and in this video, I dive deep into why so many people experience tiredness on these meds, the science behind it, and—most importantly—what you can do to overcome it and get your energy back.

I cover everything from calorie restriction and dehydration to hormone and mitochondrial slowdown, and even the toxic load released during rapid fat loss. Whether you’re new to GLP-1s or have hit an energy wall, this is the comprehensive review you need!

Timestamps:

0:00 – Intro: Why are GLP-1 users so fatigued?
1:33 – What are GLP-1s, and why do people use them?
2:30 – How common is fatigue on GLP-1s?
3:24 – Who gets prescribed GLP-1s and why fatigue might be worse for some
4:10 – Calorie restriction and appetite suppression
5:43 – Metabolic adaptation: Why your metabolism slows down
6:20 – Nutrient deficiencies and low protein
7:37 – Weight loss itself: Why rapid fat loss can make you feel weak
7:41 – Dehydration and electrolyte imbalances
8:39 – Reduced thirst and GI side effects
9:56 – Blood sugar fluctuations and hypoglycemia
11:03 – Brain effects: Dopamine, mood, and motivation
12:15 – Hormonal changes: Leptin, thyroid, testosterone
13:40 – Neurological factors: GLP-1 in the brain
15:49 – The “detox effect” of rapid fat loss
17:06 – How toxin release and inflammation cause fatigue
18:47 – Mitochondrial slowdown: Why you feel so flat
20:45 – Practical fixes: What to do about GLP-1 fatigue
22:57 – How to eat, hydrate, and adjust your dose
24:15 – Timing your injections and microdosing
25:30 – Circadian rhythm, sunlight, and lifestyle tips
26:42 – Closing thoughts and community feedback

If you’ve experienced fatigue or brain fog on GLP-1s, comment below—share what worked for you! And if you want a deeper dive into peptides, hormones, and biohacking, grab my free peptide cheat sheet in the description and join Fully Optimized Health, the best community for health optimization.

Thank you for being here—I’m grateful for every one of you! If you found this helpful, like, comment, and subscribe for more science-backed content.