Dr. Kara Fitzgerald talks with Sergey Young, founder of the Longevity Vision Fund and XPRIZE board member, about the future of aging medicine. Hear how AI, wearables, new diagnostics, and early screening are making longevity solutions more practical, affordable, and clinically relevant for functional medicine practitioners.

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS

Sergey Young is a longevity investor, author, and visionary committed to extending healthy lifespans for one billion people. He co-founded the BOLD Longevity Growth Fund, wrote the bestseller The Science and Technology of Growing Young, and serves on the boards of XPRIZE and AFAR.

Website: https://sergeyyoung.com/

Follow Sergey: @sergeyyoung200

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Hair loss is more than cosmetic. In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald explores new research on the OS-01 peptide and its role in targeting senescent cells. Learn how peptide therapy compares to minoxidil, and how hormones, thyroid health, stress, UV exposure, and the scalp microbiome all play a role in thinning hair. Carolina Reis Oliveira, PhD, co-founder of OneSkin, shares insights on how polyphenols, prebiotics, and integrative strategies can support healthier growth.

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS

Carolina Reis Oliveira, PhD - OneSkin Co-Founder & CEO

Carolina Reis Oliveira, PhD, is the CEO and co-founder of OneSkin and an advocate for healthy aging. With a doctorate in immunology, she moved from Brazil to Silicon Valley to pursue her vision of using science to prevent age-related diseases. At OneSkin, she leads pioneering research on aging biology, including the development of the proprietary OS-01 peptide, the first scientifically proven to reverse skin’s biological age.

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Interested in reclaiming your roots and addressing hair thinning? Visit https://oneskin.co/DRKARA for 15% off your purchase of OneSkin’s OS-01 HAIR peptide scalp serum.

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Have you ever struggled to understand why some patients just don’t respond as expected, even when you’re following all the usual gut protocols? In this episode, I sat down with Dr. Tom Fabian, who breaks down the latest insights from StoolOMX and GI-MAP testing and shows us how to put them into practice for our most complex cases.

We dive into how identifying specific types of inflammation, bile acid patterns, and microbial imbalances can guide more precise interventions, whether it’s introducing fiber, addressing biofilms, or supporting secondary bile acid production. Dr. Fabian makes the science practical, helping us see not just what’s happening in the gut, but what to do about it in real-world clinical settings. ~DrKF

FOLLOW ALONG WITH THE CONVERSATION!

Curious about the StoolOMX Add-On to GI-MAP? Head to http://tinyurl.com/StoolOMX to download the StoolOMX Reference Guide to better understand results and create effective, actionable protocols

Listeners, join me and Dr. Tom Fabian for a free webinar on October 23rd 2025 and get your questions answered on all things on all things bile acids, pattern recognition on functional stool testing and precision-based interventions for optimal gut health and longevity. Register here: ​​https://tinyurl.com/ydzsh6y6

Check out the show notes at www.drkarafitzgerald.com/fxmed-podcast/ for all the relevant links and resources.

GUEST DETAILS

Thomas Fabian, PhD, CNTP

Email: [email protected]

Dr. Tom Fabian, PhD, is a translational scientist focused on applying microbiome research in functional and integrative medicine. He serves as a consultant and science advisor with Diagnostic Solutions Laboratory, sits on the Science Advisory Board at Designs for Health, and is a certified Nutrition Therapy Practitioner.

THANKS TO OUR SPONSOR

Diagnostic Solutions Laboratory: https://tinyurl.com/2shv9jth

Phone: 877-485-5336

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Can functional medicine unlock the secrets to healthy aging? In this special preview of the Functional Medicine is Longevity Medicine™ Masterclass happening on September 17- September 19, 2025, Dr. Kara Fitzgerald sits down with three leading voices in medicine and research:

- Dr. Bob Rountree: functional medicine pioneer in integrative approaches to health

- Dr. Dale Bredesen: internationally recognized expert on Alzheimer’s prevention and reversal

- Dr. Charles Serhan: Harvard researcher on inflammation resolution and aging biology

Together, they explore how functional medicine reframes longevity by addressing root causes, supporting cognitive health, and resolving chronic inflammation.

Whether you’re a clinician, health professional, or simply passionate about living longer and healthier, this conversation offers a glimpse into the science and practical applications that are transforming longevity medicine.

WATCH NOW TO LEARN:

- Why functional medicine is central to extending healthspan

- The latest insights on Alzheimer’s prevention and brain health

- How inflammation resolution impacts aging and chronic disease

- What to expect in the full Functional Medicine is Longevity Medicine™ Masterclass

Learn more & register for the Masterclass here: www.functionalmedicineislongevitymedicine.com

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It was a pleasure to sit down with Dr. Nir Barzilai for a conversation that turned out to be both lively and thought-provoking. His decades of research on centenarians, biological age, and the hallmarks of aging have shaped how we think about longevity—and what’s possible when we start targeting aging itself, not just individual diseases.

We get into the science behind why some people live 20–30 years longer and healthier, and what it means to measure the biological age of individual organs. But we also hit a few sparks—especially when it comes to nutraceuticals and the role of metformin in prevention. I don’t agree with everything you’ll hear, and I followed up with Dr. Barzilai afterward to unpack some of the more provocative claims. We may just need a second round for this one... stay tuned.

Check out the show notes at www.drkarafitzgerald.com/fxmed-podcast/ for all the relevant links and resources. ~DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS

Nir Barzilai M.D.

Director of the Einstein Institute for Aging Research

Professor of Medicine and Genetics

President of the Academy for Health & Lifespan Research

Website: https://einsteinmed.edu/faculty/484/nir-barzilai

Email: [email protected]

Dr. Nir Barzilai is a pioneer in aging science, known for his work on centenarians, the biology of aging, and the TAME trial. He is Director of the Institute for Aging Research at Albert Einstein College of Medicine and author of Age Later and has published over 330 papers.

THANKS TO OUR SPONSORS

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Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

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I’ve been watching the science behind Calocurb evolve over the last year, and I have to say—this is one of the most exciting clinical tools I’ve seen emerge in the metabolic space in quite some time. A hops-derived compound that stimulates endogenous GLP-1, CCK, and PYY—without a prescription or injection? That’s a big deal, especially for patients struggling with appetite regulation, weight plateaus, or the aftermath of GLP-1 discontinuation.

In this episode, I sit down with Sarah Kennedy, founder of New Zealand-based Calocurb, to talk about the years of government-funded research that led to this discovery, the remarkable clinical outcomes they’ve seen so far, and how I’ve personally used it in my practice with excellent results. If you’re looking for science-backed, natural strategies to support appetite control, fasting, or GLP-1 transitions—this one’s worth a listen. ~DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS

Sarah Kennedy, Founder and CEO of Calocurb Ltd.

Email: [email protected]

LinkedIn: https://www.linkedin.com/in/sarah-kennedy-0a840b13/

Sarah Kennedy, BVSc, is a veterinarian and health industry leader with 20+ years in nutrition science and innovation. Now CEO of Calocurb, she brings a unique perspective on natural GLP-1 activation—bridging plant-based research, gut physiology, and clinical application.

THANKS TO OUR SPONSOR: Calocurb

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Manage cravings and feel full faster with Calocurb, a 100% natural capsule that supports healthy weight management. Visit http://calocurb.com/drkara10 and use code DRKARA10 at checkout.

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Join Dr. Kara Fitzgerald and leading experts *LIVE on Sept 17–19, 2025* for a free virtual Masterclass on redefining healthcare & longevity through the lens of science-backed, systems-based approach. Register now: https://www.functionalmedicineislongevitymedicine.com/

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

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Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

In this very special episode, I have the privilege of turning the tables on Dr. Kara Fitzgerald as we celebrate 10 years of the New Frontiers podcast. I’ve been honored to walk alongside Kara on much of this journey—as a colleague, a collaborator, a mentee, and a friend—and it’s been incredible to witness the evolution of both her work and the field itself.

Together, we reflect on the stories, science, and people who have shaped this podcast—and the remarkable growth of epigenetics, personalized medicine, and functional medicine along the way. From early conversations around methylation and aging to hosting pioneers like Dr. Jeff Bland, Dr. Sidney Baker, and Dr. Charles Serhan, New Frontiers has become a living archive of how this field has moved forward.

As we talked about during the conversation: “Everybody is a piece of this ecosystem, and everybody has their role... It’s really cool to be part of that community.” This episode is a celebration of that collective journey—and a look at where we’re headed next. ~Romilly Hodges MS CNS

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

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Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. https://tinyurl.com/4f8t7jt6

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Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

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Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

This is a really exciting conversation with Dr. Davide D’Amico from Timeline, where we’re taking a closer look at Urolithin A and heart health. It should come as no surprise that this mitochondrial wonderkin of a nutrient is showing promise here—especially when you consider that 40% of the heart’s weight is mitochondria. That’s an extraordinary factoid, and one that really shifts how we think about aging in the cardiovascular system.

What’s particularly compelling in this new preclinical research is that restoring mitochondrial function may do more than just improve ejection fraction. It may also have ripple effects on other hallmarks of aging—like chronic inflammation, cellular stress signaling, and impaired autophagy. I’m thrilled Timeline is continuing to invest in both preclinical and clinical research on this front—and yes, I’m totally nerding out over what they’re up to. ~DrK

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS

Davide D'Amico, PhD: Director of Discovery and Translational Research at Timeline.

With over 15 years of experience in mitochondrial and aging biology, he contributed to developing Urolithin A as a science-backed, clinically validated nutritional product to enhance mitochondrial and muscle health.

THANKS TO OUR SPONSOR

Timeline: http://Timeline.com/kara10

Email: [email protected]

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Mitopure is making impressive strides for cellular health and longevity. Get 10% off your first order at http://Timeline.com/kara10 with code Kara10.

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Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

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Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

This episode is a little different from what we usually cover on New Frontiers, but it’s one I couldn’t wait to bring to you. I’ve been thinking a lot about how we—as clinicians—are supposed to keep up in this era of high-throughput technology. We’re swimming in data: labs, multi-omics, diet logs… and an ever-growing stream from wearables. There’s just so much coming at us, and too often, we’re awash in a sea of information without adequate interpretive power.

That’s why this conversation with Dr. Rana el Kaliouby felt so important. She’s not just an AI scientist—she’s a visionary and a total badass. She’s building technology that doesn’t just process data, but actually helps us become better clinicians and better humans. We get into the ethics, the potential, the parenting implications—and yes, a personal story about a tragedy in my own hometown that made this all hit very close to home. This one’s powerful, and I hope it sparks the same questions and inspiration for you as it did for me. ~DrKF

TRIGGER WARNING

This episode touches on sensitive topics, including gun violence and suicide, in the context of empathy, mental health, and technology. If you or someone you know is struggling, please seek help. We share this with care and hope it offers support and perspective.

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS

Dr. Rana el Kaliouby: http://www.ranaelkaliouby.com

Managing Partner, Blue Tulip Ventures: http://www.bluetulip.vc

Host, Pioneers of AI Podcast: https://www.pioneersof.ai/

Author of Girl Decoded

Dr. Rana el Kaliouby is an Egyptian-American AI scientist, entrepreneur and investor. She is co-founder and Managing Partner of Blue Tulip Ventures, where she invests in startups building Human-Centric AI, and host of the Pioneers of AI podcast. Prior to that, Rana founded her company Affectiva out of MIT, where she pioneered the field of Emotion AI, and successfully exited the company in 2021. She holds a Ph.D. from the University of Cambridge and a Post Doctorate from MIT.

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DIAMOND

Biotics Research: https://www.bioticsresearch.com/

DUTCH: https://dutchtest.com/for-providers

GOLD

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TimeLine Nutrition: https://tinyurl.com/bdzx2xms

EXCLUSIVE OFFERS FROM OUR SPONSORS

OneSkin: Get 15% off OneSkin with the code DRKARA at http://oneskin.co/DRKARA

Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. https://tinyurl.com/4f8t7jt6

CONNECT with DrKF

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

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Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

In many ways, the legal side of functional medicine can feel like the Wild West—uncertain, unregulated, and full of risks. The reality is, we all want to have our practices legally buttoned up, but navigating the legal landscape can feel overwhelming—and expensive. What Scott Rattigan, creator of Functional Lawyer, shares in this episode is a real game-changer. He not only breaks down the complexities of the legal side of things but also offers real solutions for us—solutions that can make sure we're covered without the stress and uncertainty that often comes with it. Whether you're just starting out or growing your established practice, you're going to get actionable insights on how to avoid common legal pitfalls, protect your practice, and actually move forward with confidence. It’s a topic that’s been an unmet need for so long, and I'm so excited to bring this to you. ~DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS

Download 5 Essential Legal Documents for Every Functional or Integrative Medicine Practice: https://www.functionallawyer.com/resource-downloads

GUEST DETAILS

Scott Rattigan, JD

Founder: Functional Lawyer: https://www.functionallawyer.com/kf

Co-founder: Origins Incubator - https://www.originsincubator.com/

The Junto Podcast Playlist: https://fxmedlaw.com/junto-youtube

LinkedIn: https://www.linkedin.com/in/scott-rattigan/

Email: [email protected]

Phone: 941-229-0928

Scott Rattigan, JD, is the founder of Functional Lawyer, offering flat-rate legal solutions to help practitioners protect their licenses and grow their businesses. Inspired by helping his wife build her functional medicine practice, Scott provides high-quality legal support for health coaches, doctors, and more. He’s an attorney, internationally recognized speaker, host of The Junto with Scott Rattigan, bestselling author of The Practice of Telemedicine, and co-founder of the practice success software ReveliaDx.

THANKS TO OUR SPONSOR

Functional Lawyer: https://www.functionallawyer.com/kf

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Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

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DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw