Working Towards Delayed Primary Closure.
Once the decision is made to leave an abdominal wound open, in addition to all the other
clinical challenges that require addressing, one goal should remain in the forefront of the
clinicians thinking and that is ultimate closure. It is essential that there is regular evaluation
and re-evaluation of the abdominal contents and the wound environment to ultimately
facilitate primary fascial closure or functional abdominal closure.
Many patients will progress to sutured primary fascial closure without difficulty. There will
however be many patients who end up with more complex wounds including wide fascial
defects with lateralisation of the muscle wall and loss of tissue domain or associated with
enteric fistulae. By definition these latter wounds are contaminated and therefore use of
mesh to assist closure can be fraught with potential septic complications.
In this complex group many clinicians will opt for a staged approach to abdominal wall
reconstruction. This involves a combination of component separation and fascial closure (or
at least partial closure) with the addition of an absorbable mesh either as an onlay or ?bridge?.
The trade off with this approach is avoiding infection in a permanent mesh set against the
almost inevitable ventral herniation at a later date. The patient will then often require another
major operation to close the hernia with permanent mesh at a later date. Clearly re-operating
on these patients is difficult and again fraught with the danger of significant complication
including of course further intestinal fistulation.
To date there has been no alternative to this staged approach. That is until the arrival of a
regenerative biological mesh STRATTICE. This mesh has been designed or processed in a way
that it has lost its antigenicity but retains the ability to support revascularisation and cellular
repopulation along with white cell migration. This allows it to be used in the presence of local
contamination such as that found in these complex open wounds.�
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World Society of The Abdominal Compartment Syndrome (WSACS). Part 1. Defintions.Results from the international
conference of experts on intra-abdominal hypertension and abdominal compartment syndrome. Intensive Care Med 2006; 32(11):1722-1732.
World Society of The Abdominal Compartment Syndrome (WSACS). Part 2. Recommendations. Results from the
international conference of experts on intra-abdominal hypertension and abdominal compartment syndrome. Intensive Care Med 2007; 33(6): 951-62.