Ads for Ozempic, Wegovy, and Zepbound are all over our televisions (at least here in the US). But are these injectables really the key to losing weight and keeping it off?

In this episode, I'm digging into all of the science surrounding these popular weight-loss drugs, including

- the differences between each of them

- how they work (and don't work)

- the unwanted side effects that come from using these medications

- natural ways to increase your body's production of GLP-1

... and more!

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Show Notes:

References:

Coursework from Master’s in Human Nutrition & Functional Medicine Program at the University of Western States

Efficacy and safety of GLP-1 receptor agonists versus SGLT-2 inhibitors in overweight/obese patients with or without diabetes mellitus: a systematic review and network meta-analysis

Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension

Weight Loss Medications: GLP-1 Agonists and How They Work

How Much Does Ozempic Cost? With & Without Insurance

Zepbound vs. Ozempic: 5 Differences Between These Weekly Injections

What Are Incretin Mimetics, and How Do They Affect Weight Loss, Blood Sugar, and Type 2 Diabetes?

Strategies for minimizing muscle loss during use of incretin‐mimetic drugs for treatment of obesity

The Positive Effects of Yerba Maté (Ilex paraguariensis) in Obesity

Anti-obesity effects of Yerba Mate (Ilex Paraguariensis): a randomized, double-blind, placebo-controlled clinical trial

The effect of psyllium on fasting blood sugar, HbA1c, HOMA IR, and insulin control: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials

Soluble fibers from psyllium improve glycemic response and body weight among diabetes type 2 patients (randomized control trial)

Increased glucagon-like peptide-1 secretion may be involved in antidiabetic effects of ginsenosides

Modulation of glucagon-like peptide-1 release by berberine: in vivo and in vitro studies

The effects of berberine on inflammatory markers in Chinese patients with metabolic syndrome and related disorders: a meta‑analysis of randomized controlled trials

Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

A High Dose of Dietary Berberine Improves Gut Wall Morphology, Despite an Expansion of Enterobacteriaceae and a Reduction in Beneficial Microbiota in Broiler Chickens

Berberine enhances the AMPK activation and autophagy and mitigates high glucose-induced apoptosis of mouse podocytes

Curcumin induces secretion of glucagon-like peptide-1 through an oxidation-dependent mechanism

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135: What You Should Know Before Starting Ozempic

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