Pre-order ADHD and Women by Dr. Jolene Brighten and discover how hormones shape focus, motivation, executive function, and emotional regulation ⁠http://drbrighten.com/adhdandwomen

In early 2020, my life completely changed when I contracted COVID-19. As a doctor, I thought I knew what to expect—but my symptoms didn't look like anything on the news. Instead of a cough or high fever, I experienced a subtle, terrifying decline in my ability to breathe. When I finally went to the ER, a physician stood across the parking lot and told me to get my affairs in order.

But that was just the beginning. What followed was a debilitating, multi-system shutdown known as Long COVID—bringing crushing fatigue, brain fog, POTS, and nerve pain.

In this episode, I’m pulling back the curtain on my personal health journey and the exact cellular framework I used to rebuild my body from the ground up. I break down the emerging science behind viral mitochondrial damage and the four-part protocol (focusing on oxidative stress and ATP production) that helped me reclaim my life.

If you are currently fighting Long COVID or feeling dismissed by medicine, please know you are not alone. Let's talk in the comments below.

Links & Resources:

Persistent Suppression of Oxidative Phosphorylation & Mitochondrial Changes in Post-COVID Conditions (Frontiers in Immunology): https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2026.1776555/full

Mitochondrial metabolic rescue in post-COVID-19 syndrome: MR spectroscopy insights and precision nutritional therapeutics: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1597370/full

NIH RECOVER Initiative Findings on Post-Exertional Malaise: https://www.nih.gov/news-events/news-releases/nih-launches-long-covid-clinical-trials-through-recover-initiative-opening-enrollment

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Disclaimer: I am a board-certified doctor, but I am not your doctor. The information provided in this video is for educational, informational, and personal storytelling purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard in this video.

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Endometriosis and Endometriomas are often misunderstood, leaving many women without answers for years. In this episode, Dr. Jolene Brighten sits down with endometriosis surgeon Dr. Amanda Chu, MD, to discuss how endometriomas may signal more advanced disease, why they're frequently dismissed, and what every woman should know about diagnosis and treatment. For the complete research, resources, and show notes, visit https://drbrighten.com/podcasts/endometriomas-and-endometriosis/

If you've been told it's "just a cyst," have been sent home from the ER without answers, or wonder whether surgery is the right next step, this conversation will help you better understand your options and how to advocate for yourself.

👩‍⚕️ About Today's Experts

Dr. Jolene Brighten, NMD, FABNE is a board-certified naturopathic endocrinologist, Certified Menopause Specialist through The Menopause Society, bestselling author, and internationally recognized leader in women's hormone health.

Dr. Amanda Chu, MD is a fellowship-trained minimally invasive gynecologic surgeon specializing exclusively in endometriosis excision surgery. She is recognized for her expertise in complex endometriosis, fertility preservation, and advanced pelvic surgery.

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Endometrioma may be one of the most overlooked signs of advanced endometriosis—and it could have major implications for pain, fertility, ovarian reserve, and long-term health. For full show notes, resources, and links mentioned in this episode, visit https://drbrighten.com/podcasts/endometrioma/.

In this episode of The Dr. Brighten Show, I sit down with endometriosis specialist and minimally invasive gynecologic surgeon Dr. Amanda Chu to discuss what an endometrioma really is, why it's often called a "chocolate cyst," how it may impact fertility, and why many women are told not to worry about these cysts when they may actually be a sign of deep infiltrating endometriosis. We also discuss ovarian reserve, cancer risk, hormone therapy, surgical options, nutrition, inflammation, and the challenges women continue to face when seeking diagnosis and treatment.

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Struggling with hot flashes, sleep disruptions, brain fog, or other menopause symptoms? Alloy is a digital health platform that connects you with menopause-specialized doctors who create personalized treatment plans—all from the comfort of home.

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Overthinking at night can feel like anxiety, but for many women, racing thoughts, waking up at 3 AM, and feeling exhausted but unable to sleep may be connected to cortisol, blood sugar, ADHD, hormones, and nervous system dysregulation. View the full show notes at

In this episode of The Dr. Brighten Show, Dr. Jolene Brighten, board-certified in naturopathic endocrinology, Certified Menopause Specialist through The Menopause Society, certified sex counselor, and author of the upcoming book ADHD and Women, explains why your brain may feel loudest the moment your head hits the pillow.

Drawing on her clinical experience working with women navigating ADHD, perimenopause, hormone changes, insomnia, and chronic stress, Dr. Brighten explains why your nighttime anxiety may not be “just anxiety.” You’ll learn how cortisol dysregulation, blood sugar crashes, estrogen and dopamine changes, progesterone and GABA, hypervigilance, and an overburdened nervous system can all contribute to that “wired but tired” feeling.

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For the nights when your body is exhausted but your brain missed the bedtime memo, Adrenal Calm helps support a calmer stress response and deeper, more restorative sleep.

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Struggling with hot flashes, sleep disruptions, brain fog, or other menopause symptoms? Alloy is a digital health platform that connects you with menopause-specialized doctors who create personalized treatment plans—all from the comfort of home.
Join the 95% of women who experienced symptom relief within the first two weeks. Visit https://www.myalloy.com/ and use code DRBRIGHTEN to get $20 off your first order. You'll receive a customized treatment plan and unlimited messaging with your doctor.

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Pre-order ADHD and Women by Dr. Jolene Brighten http://drbrighten.com/adhdandwomen and discover how hormones shape focus, motivation, executive function, and emotional regulation.

Have you ever found yourself snapping at your partner, feeling annoyed by your kids, or becoming irrationally frustrated by something as simple as a dirty dish in the sink—and then immediately wondering, What is wrong with me? If so, you're not alone. In this episode of The Dr. Brighten Show, Dr. Jolene Brighten explores a question that countless women quietly ask themselves: Why am I so irritated all the time? Through the lens of women's health, hormones, emotional well-being, and nervous system function, she reveals why irritability is often not a personality flaw but an important signal from the body.

Many women assume that constant irritability means they're becoming impatient, short-tempered, or less kind. But what if irritation isn't the problem? What if it's actually a messenger pointing toward unmet needs, hormonal shifts, emotional exhaustion, chronic stress, or the invisible load so many women carry every day? In this deeply validating episode, Dr. Brighten discusses the emotional and physiological factors that can influence mood, resilience, and reactivity while offering a powerful framework for understanding yourself with greater compassion.

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When it comes to hormone therapy and breast cancer, few topics create more confusion, fear, and conflicting information. Women are often told they need to be concerned about breast cancer risk, yet many never receive a nuanced discussion about screening, lifestyle factors, inflammation, environmental exposures, or how to evaluate their individual risk profile. In this episode of The Dr. Brighten Show, Dr. Jolene Brighten sits down with former breast surgeon Dr. Jenn Simmons to discuss breast cancer screening, hormone therapy, risk assessment, inflammation, lifestyle factors, and the questions women should be asking about their long-term health.

This conversation explores both conventional and emerging perspectives on breast health while emphasizing the importance of individualized care and informed decision-making. Women listening to this episode will gain insight into current screening conversations, breast cancer risk factors, lifestyle interventions, metabolic health, environmental exposures, and the role of personal empowerment in supporting long-term wellness.

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Want science-backed supplements formulated by a doctor who actually understands women’s health? 🌿 At Dr. Brighten Essentials, every product is crafted to support your hormones, boost your energy, and help you feel your best—inside and out. From targeted nutrients for glowing skin to essentials that fuel your daily vitality, you’ll get the highest-quality ingredients in forms your body can truly use.

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Shop now → https://drbrighten.com/lumebox use code drbrighten for our exclusive community discount on your purchase.

LMNT Electrolytes 

Want a clean, science-backed way to stay hydrated and energized? At LMNT, electrolytes are formulated with a precise balance of sodium, potassium, and magnesium — with no sugar, no artificial ingredients, and no unnecessary fillers. Designed to support hydration, muscle function, and daily energy, LMNT helps you feel your best through workouts, busy days, and everyday life.

Exclusive for podcast listeners: Visit http://drinklmnt.com/Brighten to receive a free sample pack with any purchase.

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My new book, ADHD and Women, is now available for pre-order! Learn how hormones influence ADHD symptoms and get your copy here: http://drbrighten.com/adhdandwomen

End picky eating with practical, root-cause strategies from integrative pediatrician Dr. Elisa Song, MD, and view the full show notes at DrBrighten.com: https://drbrighten.com. In this episode of The Dr. Brighten Show, Dr. Jolene Brighten and Dr. Song discuss picky eating, zinc, gut health, sensory food aversions, and simple ways parents can help kids expand their diet with less stress.

👩‍⚕️ Dr. Elisa Song, MD, joins Dr. Brighten to explain why picky eating may be more than “just a phase” and how nutrient status, the gut microbiome, sleep, movement, and nervous system regulation can influence a child’s food preferences.

In This Episode, You’ll Learn:

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🌟 Grab my free hormone friendly recipes here! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drbrighten.com/hormonekit/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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What if the IVF missing piece is not only the embryo—but the environment that embryo is trying to implant into? In this powerful episode of The Dr. Brighten Show, Dr. Jolene Brighten sits down with Dr. Gerardo Barroso Villa, a world-renowned fertility expert and reproductive biologist, to talk about recurrent miscarriage, IVF, endometritis, sperm health, PGT-A, and why fertility care should look at the full picture—not just the egg.

Dr. Barroso brings an extraordinary depth of expertise to this conversation. He is introduced as a fertility expert and reproductive biologist trained at prestigious institutions including the Jones Institute for Reproductive Medicine and Cornell University, with advanced expertise in microsurgical male factor treatment and IVF techniques, a doctorate from Eastern Virginia Medical School, more than 2,500 international citations for his research, and experience serving as an ad hoc reviewer for leading medical journals.

Together, Dr. Brighten and Dr. Barroso unpack one of the most emotionally loaded and medically complex topics in reproductive health: why miscarriages happen, what may be missed in recurrent pregnancy loss, and how a more complete fertility workup may help couples make more informed decisions.

This Episode Is Brought to You By

Dr. Brighten Essentials Prenatal Plus

Want a science-backed prenatal that is designed to support women through preconception, pregnancy, and postpartum. Prenatal Plus is thoughtfully formulated with active B vitamins, well-absorbed nutrients like methylated folate, iron, iodine, and essential minerals to help support energy, hormone health, and healthy development. This vegan, non-GMO, and third-party tested formula is designed to support your body through every stage of motherhood.

Exclusive for podcast listeners: use the code POD15 for 15% off your order

Shop now https://drbrightenessentials.com/products/prenatal-plus

Natural Cycles

The first, and currently the only FDA-cleared birth control app. It’s completely hormone-free, science-backed, and designed to make tracking your cycle and fertility simple and stress-free.

Using a certified algorithm, the app analyzes hormone-driven changes in your body temperature to learn your unique cycle pattern and confirm your daily fertility status. This helps remove much of the guesswork and human error that can come with traditional fertility awareness methods.

Whether you’re looking to prevent pregnancy or plan for one, Natural Cycles offers a personalized, non-invasive approach to understanding your body.

Use code DrBrighten to get 15% off an annual subscription plus a free Bluetooth thermometer.

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HigherDOSE – Red Light Showerhead Filter

Your shower water could be impacting your skin more than you think. The HigherDOSE Red Light Showerhead Filter features a 10-stage filtration system designed to reduce chlorine, VOCs, and other contaminants that can contribute to dryness and irritation. It also includes built-in red light therapy to support cellular energy and overall skin appearance—turning your daily shower into a more restorative ritual.

Save 15% at http://higherdose.com/drbrighten and use code DRBRIGHTEN15 for 15% off

Connect with Dr. Gerardo Barroso Villa:

Clinic Website https://nascere.org.mx/

Instagram https://www.instagram.com/clinicanascere

YouTube https://www.youtube.com/@clinicanascere

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🌟 Grab my free hormone friendly recipes here! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drbrighten.com/hormonekit/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬

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I'm hosting a live PMDD Relief Workshop on June 10th, free when you pre-order ADHD and Women. Get your spot at https://drbrighten.com/pmdd

What if your brain fog, low mood, and poor focus were not just “in your head,” but connected to what is happening in your immune system, gut microbiome, and daily food choices? In this episode of The Dr. Brighten Show, Dr. Jolene Brighten sits down with Dr. Austin Perlmutter to unpack the connection between brain inflammation and food, including why the brain is literally built from the nutrients you eat, how added sugar may influence systemic inflammation, and why the gut-brain connection is one of the most important conversations in brain health right now.

Dr. Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, and Managing Director of Big Bold Health. His work focuses on brain and body health, including the biological roots of mental and physical “stuckness,” how environmental factors shape cognitive and emotional well-being, and how plant nutrients may impact human aging through epigenetics. His work has reached millions through media outlets including PBS, Rolling Stone, and NPR.

In this episode, Dr. Perlmutter and Dr. Brighten explore how brain inflammation, nutrition, the microbiome, stress, sleep, exercise, air quality, social media, and daily habits all intersect. But the heart of this conversation is simple and powerful: your brain is not separate from your body. It is built from the food you eat, shaped by the microbes you feed, and influenced by the inflammatory signals your body produces every day.

This Episode Is Brought to You By

Dr. Brighten Essentials Radiant Mind

Your brain deserves support every day—not just when your focus disappears, your motivation crashes, or your hormones decide to make executive function feel like a full-contact sport. Radiant Mind by Dr. Brighten Essentials was formulated to support cognitive function, mental clarity, and a healthy stress response, making it a perfect companion to today’s conversation about estrogen, dopamine, focus, and women’s brain health.

Get Radiant Mind here https://drbrightenessentials.com/products/radiant-mind

Sunlighten Saunas

Supporting your brain and hormones isn’t only about what you take—it’s also about how you support your body’s resilience. Sunlighten Saunas are designed to help you create a restorative wellness ritual at home, supporting relaxation, sweating, and recovery. For women navigating stress, perimenopause, and the daily demands on the nervous system, having a consistent way to unwind can be a powerful part of your self-care routine.

Learn more about Sunlighten Saunas here https://get.sunlighten.com/drbrighten

OneSkin

Founded by an all-woman team of PhD-level scientists, OneSkin is revolutionizing aging with the OS-01™ peptide, the first ingredient proven to reverse skin’s biological age by targeting cellular senescence. The result? Skin that looks, feels, and acts younger. It’s never too early — or too late — to invest in your skin health.

Shop now https://oneskin.pxf.io/c/1950532/2885132/31050

Connect with Dr. Austin Perlmutter:

Website: https://www.austinperlmutter.com

Instagram: https://www.instagram.com/draustinperlmutter

👩🏻‍⚕️Follow Dr. Jolene Brighten:

💻 Website:⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drbrighten.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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🧵Threads: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.threads.net/@drjolenebrighten⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

🌟 Grab my free hormone friendly recipes here! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drbrighten.com/hormonekit/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬

Learn more about your ad choices. Visit megaphone.fm/adchoices

I'm hosting a live PMDD Relief Workshop on June 10th, free when you pre-order ADHD and Women. Get your spot at https://drbrighten.com/pmdd

Most women with endometriosis are told their imaging is "normal" — sometimes for years, sometimes for decades — while the disease silently progresses through their body. When Bryan Johnson posted a viral photo of his girlfriend Kate Tollo undergoing a transvaginal ultrasound, it exposed more than just one couple's private medical moment. It exposed how little most people — including those with enormous platforms — understand about what proper endometriosis imaging and diagnosis actually require.

In this episode, I respond to that viral post and use it as a teaching moment. I walk through why normal imaging can never rule out endometriosis, how most radiologists miss the disease entirely, and what the right diagnostic pathway actually looks like. I also share my own story of being dismissed as "attention-seeking" by a radiologist — only to be diagnosed with stage four endometriosis.

You'll learn:

- Why a "normal" ultrasound or MRI does not rule out endometriosis — and what gets missed when general radiologists read your scans

- What an ENZIAN score is, why it matters more than the I–IV staging system for surgical planning, and how to request one

- The three types of endometriosis (endometriomas, deep infiltrating, and superficial/peritoneal) — and which ones imaging can and cannot detect

- Why endometriosis is a full-body inflammatory disease linked to a 20–60% increased risk of cardiovascular disease, stroke, and blood clots

- The embryological rest theory: why endometriosis can occur without a uterus, and why you don't need to have a period to have this disease

- The mast cell, histamine, and estrogen feedback loop that drives lesion growth and systemic inflammation

- How to vet your radiologist, why an "endometriosis protocol" at an imaging center isn't a guarantee, and what questions to ask before surgery

- Why the birth control pill and Lupron are symptom management tools, not treatment — and what true treatment actually requires

- What proper pre-surgical imaging looks like — from transvaginal ultrasound at a center of excellence to ENZIAN-scored expert reads — and why it's the difference between a planned surgery and waking up to surprises

This episode will change how you think about endometriosis diagnosis — and what you demand from your next scan.

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