For our 300th episode of Forensic Tales, we’re tackling one of the most infamous and puzzling unsolved cases in American history—the Zodiac Killer. Between 1968 and 1969, a mysterious figure terrorized Northern California with a string of murders, chilling phone calls, and cryptic letters sent to local newspapers. Despite decades of investigation, the Zodiac’s identity remains one of the greatest mysteries in true crime.

In this milestone special, we’ll retrace the Zodiac’s crimes and focus on the forensic evidence: the ballistics that linked his attacks, the fingerprints and palm prints that led nowhere, the handwriting analysis that divided experts, and the DNA testing that continues to fall short. We’ll also look ahead at how advances in forensic science—like genetic genealogy—could one day solve this case.

Thank you for joining me on this journey through 300 episodes. Here’s to the stories we’ve told, the voices we’ve remembered, and the breakthroughs still to come.

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