Dr. Gary Sachs is Clinical Vice President at Signant Health and the founder of Massachusetts General Hospital's Bipolar Clinic and Research Program. He is also an Associate Clinical Professor in Psychiatry at Harvard Medical School and was the Principal Investigator of the National Institute of Mental Health's Systematic Treatment Enhancement Program for Bipolar disorder. Dr. Sachs is a Distinguished Fellow of the American Psychiatric Association. He chairs the Scientific Advisory Committee of the Depression and Bipolar Support Alliance (DBSA) also serves on DBSA board of directors. In March of 2020, he became president elect of the International Society for CNS Clinical Trial Methodology (ISCTM) Dr. Sachs has authored over 200 peer reviewed articles and is a contributor to the seminal book Managing Bipolar Disorder: A Cognitive Behavior Treatment Program Therapist Guide (Treatments That Work) which addresses the management of bipolar disorder. In March of 2020, he became President Elect of the International Society for CNS Clinical Trial Methodology. Dr Sachs is an award-winning teacher and is recognized as a "Top Doctor" by US News and World Report, and by Reuters as among the world's 100 most influential Psychiatrists, Neurologists and Neuroscientists.

Bipolar disorders are mood episodes that affect a person's ability to function, and where a person experiences an intrusive mood episode such as mania, hypomania, or depression. These changes in mood can appear as intense highs and lows and can last for days at a time or longer. They are generally well demarcated changes in mood that interrupt previous functioning, which is to be distinguished from volatile behavior that is better explained by poor characterological temperament or the psychological effects of substance abuse.

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