It’s a heavyweight NFC clash — the 49ers and Buccaneers are both dealing with injuries, but the stakes couldn’t be higher.San Francisco enters Week 6 looking to stay atop the NFC, while Tampa Bay has proven it's a resilient contender. Steph and KP break down the matchups, and Dezi joins us to discuss the key injuries that could shape this game, and what the 49ers need to do to keep control of the #1 seed.

0:00 Intros

1:41 Injury discussions

11:55 A look at Bucs' offense

12:30 Cautious: 49ers vs Bucs' pass game

27:55 A look at Bucs' defense

28:45 Cautious: 49ers vs Bucs' rushing defense

31:20 Favorable: 49ers vs Bucs' pass defense

40:45 Opportunity: 49ers vs Bucs' red zone defense

41:15 Favorable: 49ers pass rush vs Bucs' RT Charlie Heck

50:25 Score predictions & closing remarks