There’s at least one natural resource out there that’s completely finite on Earth: helium. And once we use it up, it’s gone for good. The lighter-than-air gas is in especially short supply right now, thanks to the closure of a major domestic processing facility and disruptions at a couple of plants overseas. That’s not just a problem for birthday balloons — a number of industries compete for the limited supply of helium: health care, manufacturing, the tech sector and scientific research. But those researchers are often at the back of the helium line.