Should patients with mild contrast allergy be premedicated? Learn about the recently published consensus recommendations on the management and prevention of immediate hypersensitivity reactions to contrast media from Allison Ramsey, MD, FAAAAI, and Carolyn Wang, MD. These recommendations were published in The Journal of Allergy and Clinical Immunology: In Practice and Radiology and provide both allergy and radiology perspective.  

https://www.jaci-inpractice.org/article/S2213-2198(25)00191-6/fulltext

In this episode, attendees of the recent AAAAI/WAO Joint Congress in San Diego share their highlights from the meeting with us including talks you shouldn’t miss. Recordings of talks from the Joint Congress are now available online. 

Find out more about the 2025 AAAAI/WAO Joint Congress and access the recordings.

The NIH provides the majority of funding for scientific research in all areas of medicine and the proposed budget cuts will drastically effect research now and in the future. President-Elect Carla M. Davis, MD, FAAAAI, discusses a new task force established by the AAAAI Board of Directors that will work to bring more attention to this issue and encourage all of us in allergy/immunology to take action.

Visit the website for the toolkit. 

Genetic testing in our patients with Inborn Errors of Immunity is becoming more common and this episode will help listeners better understand how to incorporate this into their practice. Sarah Henrickson, MD, PhD, walks us through who should consider testing, considerations in ordering the testing, the types of testing available and how to think through the results.

Helpful Links
ClinVar - https://www.clinicalgenome.org/
This is a website by the NIH where you can type in any gene and it will list the variants that have been identified and refer you to the papers where they have been published.

Franklin Genoox - https://franklin.genoox.com/clinical-db/home
This is a website where you can look at the gene or protein of interest and look at how the variant might change the protein structure and function and what has been published.  

GnomAD - https://gnomad.broadinstitute.org/
This is another site where you can look at a gene of interest and how the variant might affect protein structure and function.  It is run by the Broad Institute in Cambridge, MA.

MARRVEL - https://marrvel.org/
This is a website that searches multiple databases for a gene or variant and helps to determine the likelihood that a variant might cause disease.

Join us for a discussion on food challenges and early introduction of foods with Kim Mudd, BSN, MSN, who helps walk us through the nuts and bolts of these processes for clinicians and patients alike. Learn some tips and tricks to help make the process as smooth as possible.

Listen to learn about dissemination and implementation sciences from our guest Stan Szefler, MD, FAAAAI. Dr. Szefler discusses his work on school-based asthma management programs and key elements in building successful collaborations with the community.

Find out more about SA3MPROTM


Applying the dissemination and implementation sciences to allergy and immunology: A Work Group Report from the AAAAI Quality, Adherence, and Outcomes Committee

Join Tanya Laidlaw, MD, FAAAAI, for a detailed and insightful conversation about the pathophysiology of AERD as well as the diagnosis and current management strategies.  

Julie Wang, MD, FAAAAI, discusses her role as the Chair of the AAAAI Annual Meeting Program Committee for the AAAAI / WAO Joint Congress being held February 28 – March 3 in San Diego, CA, USA. She also shares what we have to look forward to at the upcoming meeting. #AAAAI25

Visit the AAAAI / WAO Joint Congress website.

Listen in as Kari Nadeau, MD, PhD, FAAAAI, engages in timely discussion on the impact of air pollution and wildfire smoke on allergic disease, including who is most at risk and ways to mitigate exposures. Dr. Nadeau is a plenary speaker at the upcoming AAAAI / WAO joint congress which is focused on Climate Change and Allergic Disease.

Caroline Sokol, MD, PhD, FAAAAI, discusses her work looking at how sensory neurons talk to the immune system and are key in initiating the allergic response. She also discusses why the allergic responses likely evolved to respond to toxins rather than worms and parasites. We also discuss the upcoming Discovery program at the AAAAI/WAO Joint Congress and advice for the next generation of scientists.