Absolute Eosinophilia: A Practical Approach is the latest activity from the CAP’s Clinical Pathology Improvement Program, also known as CPIP (https://capatholo.gy/3aIYr4K). This activity describes a pragmatic approach for the workup of eosinophilia, including the appropriate application of molecular genetic studies, explains on of the CPIP case authors, Vandita Johari, MD, FCAP, in this CAPcast interview.