Dr. Wesley Kufel presents lessons learned from a complicated patient case about the pharmacokinetics and pharmacodynamics of sulbactam-durlobactam in a critically ill patient on continuous venovenous hemofiltration infected with carbapenem-resistant Acinetobacter baumannii-calcoaceticus (CRAB) complex. Read the full text open access manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.70027

Dr. Aditi Shendre shares her team's analysis of pharmacology knowledge gaps in opioids in the maternal and pediatric populations. Surprisingly, there is substantial disparity between the most commonly researched and prescribed opioids. In particular, the opioid pharmacology knowledge gaps are larger in pregnant women and for the highly prescribed opioids hydrocodone and oxycodone. Learn valuable lessons for practice from their analysis of this data set. Read the full text manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.70024.

Join host Dr. Rob DiDomenico, JACCP associate editor, and learn how Dr. Casey C. May,  clinical associate professor at the Ohio State University College of Pharmacy, and her colleagues assessed past residency candidate letters of recommendation to draw out key themes that correlate with clinical aptitude. Listen and discover what three independent themes correlated with higher clinical case scores. Dr. Aaron Cook,  associate professor at the University of Kentucky, provides perspective based on his role as the PGY1 residency program director for many years. You'll also find meaningful tips for you as a letter of recommendation writer. Read the full-text open access manuscript in the July 2025 issue of JACCP.

Podcast host and JACCP Editor-in-Chief, Stuart T. Haines, and guests, Leigh Ann Ross, Dean and Bell Endowed Chair at the Auburn University Harrison College of Pharmacy,  and Zack Dumont, Manager of Clinical Pharmacy for the Saskatchewan Health Authority. discuss the recently released ACCP Commentary titled "Framework and recommendations to support bidirectional information sharing between community pharmacies and other health care setting.”

Here’s what you’ll learn:

• Why bidirectional information exchange between all settings of care, including community pharmacies, is important for ACCP, the pharmacy profession, and society.
• How Kotter's change management framework can be applied to achieve this goal.
• Key barriers to successful bidirectional health information exchange and potential solutions.

The ACCP Commentary was published in JACCP online in March 2025 and in the May 2025 issue of the journal.

This podcast episode discusses the economic value of clinical pharmacy services, drawing on a 30-year series of systematic reviews. It highlights the established evidence that these services improve medication use, safety, and effectiveness, while emphasizing the critical need for robust economic evaluations to demonstrate cost-effectiveness and return on investment for health systems, insurers, patients, and society. Read the full manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.70034.

The authors evaluate the efficacy and safety of emerging therapeutic strategies for CKD management, including sodium-glucose cotransporter 2 inhibitors (SGLT2i), glucagon-like peptide-1 receptor agonists (GLP-1RA), finerenone, sacubitril/valsartan, and potassium binders. Read the full text manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.70014.

Drs. Adrian Wong, Sandra Kane-Gill, and Alexandre Chan discuss their ACCP Committee work with associate editor, Dr. Alan Zillich. The committees' work resulted in two papers describing the current and future role of AI in clinical pharmacy practice, research, and scholarship. Read the full-text manuscripts: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.70004 and https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.70003.

Dr. Michael Rybak hosts authors of the 2025 Update on Antibiotic Safety in Pregnancy. Listen to what you can expect from this comprehensive review of changes and new drugs, since 2015. Access full text of the manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.70010

Learn about the decades of effort put in by Drs. Leslie Hendeles and Randy Hatton to get the ineffective oral formulation of phenylephrine removed from OTC products. Dr. Kelly Goode provides perspective on the importance of the community clinical pharmacist for optimizing patient care and understanding. Read the full manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.2080.

The goal is to reduce high-risk medication use to mitigate HF exacerbations and improve outcomes. Author Joshua Jacobs shares his teams work on determining the prevalence of prescription medication use that can exacerbate heart failure among US adults with heart failure. Read the full text OPEN ACCESS manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.4648.