Few residents receive training in informatics, but almost every laboratory faces informatics challenges. These include installing new software or a new instrument, maintaining privacy, protecting laboratory data security, and more. This fall, the CAP is introducing a new Informatics Case-Based Education (ICBE) program (https://capatholo.gy/3m3lSuz), which is designed to help pathologists get ready to succeed in their careers by providing relevant, practical education on informatics topics they commonly encounter. In this CAPcast interview, Mandy O’Leary, MD, FCAP, a member of the CAP Informatics Committee, explains the value that this program brings to pathologists. Dr. O’Leary worked to develop this new program with Dr. John Sinard, its key architect.