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109. How Psilocybin Microdosing Supports Menopause: A Brain-Based Guide
How can women navigate the emotional, cognitive, and hormonal rollercoaster of perimenopause and menopause? In this episode, April Pride explores how psilocybin microdosing may offer real support for women in midlife. From balancing neuroplasticity and mood to improving sexual function and breaking addictive patterns, this conversation highlights the science, lived experience, and emerging protocols behind psilocybin’s potential to ease this complex life stage. If you're wondering how to recalibrate your brain (not just your hormones), this episode offers data-backed, compassionate insights into how psychedelics fit into midlife care.
🔵 Key Takeaways
-Hormonal shifts in perimenopause and menopause deeply impact brain function, mood, and resilience.
-Psilocybin may support neuroplasticity, emotional regulation, and cognitive clarity during these transitions.
-Microdosing could help improve libido, body image, and intimacy—areas often impacted by hormonal decline.
-Midlife women are increasingly self-medicating with psychedelics to manage menopause-related symptoms.
-Community support and intentional protocols are critical for safe, effective microdosing.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/how-psilocybin-microdosing-supports-menopause
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset
108. Why Bong Design Matters for Modern Women: Esther Ramirez from Session Goods
What if your bong could live on your coffee table—without shame or splashback? In this 4/20 Easter special, April Pride sits down with Esther Lenore Ramirez, co-founder and CEO of Session Goods, to explore how minimalist bong design supports women who want elegant, intentional tools for cannabis. From design trade-offs (no percs, no ice pinches) to the bong’s global history, this episode reclaims what it means to be a woman who smokes. Esther shares how clean glassware, thoughtful accessories, and user-friendly dimensions offer a new kind of cannabis ritual—especially for women coming back to the plant after a long hiatus.
🔵 Key Takeaways
-Designing a bong for your lifestyle means no splash guards, no logos—just clean lines and easy cleanup.
-Session Goods took cues from wine decanters and candle bases to create pieces that blend in beautifully.
-Glass fuming, color limitations, and mouthpiece angles all matter—especially when lipstick and group sharing are in play.
-The word “bong” likely comes from Thai, but the evolution of glassblowing gave us the modern version we know today.
-Homegrown cannabis or mushroom gifts add emotional connection and storytelling to the ritual of use.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/modern-bong-design-for-women-who-smoke
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset
BONUS. LSD Benefits Explained: From Microdosing to Mind Expansion
What can LSD do for your mental health, energy levels, and inner clarity? In this episode, April Pride takes listeners through the history, effects, and emerging therapeutic use of LSD—on the day it was discovered. From personal stories (including her first full trip) to practical microdosing advice, April offers a refreshingly real look at how LSD can support midlife energy, insight, and mood regulation. You’ll also hear about the risks, historical context, and modern adaptations of this once-feared psychedelic—and why now might be the time to rethink it.
🔵 Key Takeaways
-LSD is derived from a psychoactive fungus, first synthesized in 1938 and rediscovered by Albert Hoffman on Bicycle Day.
-Benefits include enhanced perception, emotional insight, and relief from depression, anxiety, and addiction.
-Microdosing LSD (10–20mcg) may support focus and mood—April is exploring it as an alternative for ADHD meds.
-Risks include triggering latent mental health conditions—consult your doctor before use.
-Trusted sourcing, set and setting, and intention make all the difference in LSD outcomes.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/lsd-benefits-for-mind-and-mood
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset
107. Psilocybin for Menstrual Cycles and Menopause: A Women’s Wellness Protocol
How can mushrooms sync with your cycle—or shift your experience of menopause? In this episode, April Pride is joined by Jennifer Chesak, author of The Psilocybin Handbook for Women, to decode the powerful relationship between psilocybin and women’s hormones. Together, they explore the latest research, ancestral wisdom, and practical strategies for using psychedelics across different phases of a woman’s life. From syncing mushroom journeys with ovulation to microdosing through perimenopause, this conversation empowers women to tailor their approach to their unique physiology. Expect science, storytelling, and no-BS protocol advice grounded in lived experience.
🔵 Key Takeaways
-Psilocybin affects the menstrual cycle via the stress-regulating HPA axis, with possible benefits like cycle regulation or early onset.
-Optimal time to journey is near ovulation, when energy and estrogen levels support a deeper experience.
-Indigenous wisdom aligns with new science, reinforcing cycle-aware practices for safe, intentional use.
-Psilocybin can support perimenopause by easing depression, improving libido, and helping resolve trauma.
-A microdosing protocol should be personal—guided by intuition, not rules made by men.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/psilocybin-menstrual-cycles-menopause
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset
106. Natural Psychedelics and the Healing Power of Community
What if the most potent medicine isn’t just the mushroom or the ceremony—but the community that holds you through it? In this soul-stirring conversation, host April Pride continues her dialogue with healer and teacher Satya on the role of natural psychedelics in helping women heal trauma and reconnect with their core selves. From the roots of survival instinct to the chemistry of trust, they explore why healing doesn't happen in isolation—and how community care, spiritual insight, and ethical facilitation are essential to any psychedelic journey. Whether you're new to plant medicine or rethinking your own integration path, this episode grounds the mystical in the everyday and reminds us: the real work happens after the trip.
🔵 Key Takeaways
-Natural psychedelics help dissolve survival-based trauma that keeps women disconnected from themselves and others.
-True healing starts after the retreat. Integration, accountability, and sustained connection are what turn insights into change.
-Community support is non-negotiable. Healing happens in safe, nonjudgmental spaces—not in isolation.
-Facilitator integrity is critical. Training, experience, and humility must precede serving psychedelic medicine.
-We must reframe our cultural obsession with more. Sometimes awe, not intensity, is the deepest form of medicine.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/natural-psychedelics-for-trauma-healing
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset
105. Integrating Science and Spirituality: A New Framework for Psychedelic Healing
What does it mean to truly heal in a psychedelic space? In this episode, host April Pride is joined by Satya—a seasoned facilitator whose work bridges psychotherapy, meditation, and natural psychedelic therapy. Together, they unpack how conscious language, sacred space, and personalized protocols shape transformative outcomes. From working with trauma survivors and cancer patients to designing women-only retreats for deep healing, Satya reveals how integrating science and spirituality can unlock layers of self that pharmaceuticals and talk therapy alone cannot reach. If you’re questioning whether psychedelics are for you—or how to choose between a retreat with or without medicine—this episode helps you explore those decisions through the lens of compassion, integrity, and feminine wisdom.
🔵 Key Takeaways
-Psychedelic healing is not one-size-fits-all—the path begins with your needs, history, and readiness.
-Language shapes experience. Conscious facilitation means guiding, not imposing, especially during altered states.
-Cancer patients, trauma survivors, and military veterans have unique responses and needs in integration work.
-Women’s-only spaces allow for safer, deeper healing, especially for survivors of sexual trauma or body image issues.
-Science and spirituality aren’t opposites—they’re complementary tools for individual and collective healing.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/science-meets-spirit-psychedelic-healing
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset
104. How Microdosing for Women Rewires Habit, Hormone, and Healing Cycles
How does a microdose change a life? In this powerful conversation, April Pride returns with part two of her interview with guide Sand Symes to unpack what really happens when women begin a psychedelic microdosing protocol. From rewiring somatic patterns to clearing menopausal brain fog, this episode explores how subtle shifts lead to seismic inner changes. Sand shares her personal experience as well as insights from guiding others through emotional healing with psychedelics. Expect science-backed nuance, spiritual depth, and hard-won clarity on how to start integrating psychedelics into a sustainable practice—especially for women navigating midlife. Whether you're microdosing out of curiosity or crisis, this episode offers community and guidance on your path forward.
🔵 Key Takeaways
-Microdosing can quietly interrupt deeply held somatic habits, from sugar cravings to codependent relationships.
-Hormonal shifts like menopause can be softened by psychedelics—Sand describes brain fog lifting mid-protocol.
-Integration isn’t optional. It's how the medicine keeps working long after the last dose.
-Doing it alone? Not ideal. Community is key to meaningful psychedelic integration, especially for women.
-Microdosing supports spiritual clarity, emotional regulation, and better decisions—one subtle shift at a time.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/microdosing-for-women
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset
Exploring the Intersection of Psychedelics and Creativity: Live at Town Hall Seattle
In this bonus episode of the SetSet Show, recorded live at Town Hall Seattle's inaugural Psychedelic Salon, host April Pride delves into the powerful relationship between psychedelics and creativity. Alongside fine art photographer Rachel Demy and co-founder of The Stranger and The Onion Tim Keck, the trio discusses how psychedelic experiences can reshape our relationship with fear, enhance creative processes, and provide profound spiritual and personal revelations. They explore the nuances of different substances like psilocybin, ketamine, and ayahuasca, and answer thoughtful audience questions about set and setting, mental health, and more. Tune in for an honest, vibrant conversation filled with humor, wisdom, and real-world insights on unlocking creativity, healing trauma, and expanding perspectives with psychedelics.
00:00 Introduction to the SetSet Show
00:31 Live at Town Hall Seattle: Special Guests
00:48 Exploring Psychedelics and Creativity
01:17 Audience Questions and Insights
01:49 Event Announcements and Opening Remarks
02:44 Meet the Panelists: April, Rachel, and Tim
06:18 Tim Keck's Psychedelic Journey
07:02 Rachel Demy's Psychedelic Experiences
20:48 Psychedelics and Overcoming Fear
33:53 Spiritual Revelations and Audience Interaction
39:10 Creative Self vs. Tripping Self
39:25 Photography and MDMA
40:08 Writing and Problem Solving on Psychedelics
40:50 Set and Setting for Psychedelic Experiences
42:40 Stimulating Creativity with Psychedelics
44:08 Ketamine: Therapeutic Uses and Experiences
47:37 Psychedelics and Creative Work
52:06 Cultural Perspectives on Psychedelics
58:40 Solo vs. Supported Psychedelic Trips
59:54 ADHD Meds and Psychedelics
01:03:49 Curiosity About Higher Doses
01:06:39 Concluding Thoughts and Final Questions
Visit SetSet's website getsetset.com, enter SHOW20 at checkout for 20% off SetSet's Psychedelic Cards.
You can also find these clinician-backed resources on psilocybin:
The Ultimate Psilocybin Guide here
Micro-Psyched 12-week Microdosing Program here
WEB | getsetset.com
IG | @getsetset
YouTube | youtube.com/@getsetset
103. Feminine Psychedelic Power: Healing Stories from the Inside Out
In this soulful and story-rich episode, April Pride welcomes Sand Symes, a guide with decades of experience guiding women through psychedelic journeys. Together, they explore how feminine energy—when supported by plant medicine like psilocybin, cannabis, and MDMA—can become a powerful portal to emotional liberation and embodied truth. Through lived experience and clinical wisdom, Sand unpacks why traditional therapy often falls short for women and how sacred psychedelics offer a different kind of transformation—rooted in intuition, ancestry, and nervous system recalibration. If you’ve ever wondered what it looks like to prepare for a journey as a woman, or why psilocybin healing feels so personal, this conversation will meet you where you are.
🔵 Key Takeaways
-Feminine energy healing with psychedelics helps women release outdated stories embedded in their nervous systems.
-Sand Symes shares her journey from social work to sacred medicine, working with psilocybin, cannabis, and MDMA.
-Psychedelics help rewire trauma responses and open a deeper connection to ancestral and intuitive wisdom.
-The power of preparation and integration: true healing begins before and continues long after the journey.
-These medicines invite sovereignty, not escapism—women reclaim their truth through presence and self-compassion.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/feminine-energy-healing-with-psychedelics
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset
102. Is At-Home Ketamine Treatment Safe for Women with Trauma?
In this powerful second conversation with author and mental health advocate Kaia Roman, host April Pride explores the clinical, emotional, and cultural dimensions of at-home ketamine treatment—particularly for women navigating trauma, depression, and midlife transitions. With brutal honesty and personal insight, the two discuss dissociation, PTSD, accessibility, and whether at-home ketamine is a fit for women with a history of sexual trauma. This episode doesn’t shy away from the hard questions: Can ketamine help with suicidal ideation? What’s the difference between medical and spiritual dissociation? How do we keep these treatments safe, affordable, and trauma-informed? Whether you're ketamine-curious or rethinking your mental health toolkit, this episode delivers the science, story, and support you need.
🔵 Key Takeaways
-Ketamine therapy offers rapid relief for depression, PTSD, and even suicidal ideation—especially when traditional meds fail.
-At-home ketamine treatment must be guided and never done alone, especially for trauma survivors.
-Dissociation in ketamine can be healing—not retraumatizing—when properly supported.
-Initial protocols often require 4–6 sessions in 2–3 weeks, with boosters tailored to the individual.
-Ketamine is a safe, flexible tool with almost no side effects—but it's not a one-and-done solution.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/at-home-ketamine-for-women
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset
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