Have you ever wanted to get your Archimedes answer to a clinical question into our journal and onto this podcast? Did you worry that because it was about a strange device for making balloons blow up by using your nose that we’d laugh it out of the park? Well - you need not have worried - but it’s already been done (see https://adc.bmj.com/content/106/9/923.1). Same with uncertainties about single-dose old-fashioned UDP-N-acetylglucosamine enolpyruvul transferase disruptors (https://adc.bmj.com/content/106/9/925). I’ll leave this as a tease for you to have to listen to find out which antibiotic is being explored here. We cover some thoughts on using older or re-focussed therapies too (https://adc.bmj.com/content/106/9/923.2).