Ask Stago (english version)

Welcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals.  

In today’s episode, with our expert Draga Tchipeva, international application specialist, Cécile Hourquet and Audrey Carlo will start questioning how we can help the laboratory to become more productive with some middleware solutions: rules engines. 

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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals. This week, with our expert Frédéric Brutto, product line manager, Cécile Hourquet and Audrey Carlo will question HIL interferences and how the coagulation laboratory can handle them.  

Sources: 

• Lippi G et al., Interference of blood cell lysis on routine coagulation testing. Arch Pathol Lab Med. 2006;130(2):181-4 
• Woolley A et al., Effects of haemolysis, icterus and lipaemia on coagulation tests as performed on Stago STA-Compact-Max analyser. Int J Lab Hematol. 2016; 38(4): 375-88 
• Plebani M, Quality Indicators to Detect Pre-Analytical Errors in Laboratory Testing, Clin Biochem Rev 2012; 3: 85-88. 
• Salvagno GL et al, Prevalence and type of pre-analytical problems for inpatients samples in coagulation laboratory, J Eval Clin Pract. 2008 ;14(2):351-3. 
• CLSI Hemolysis, Icterus, and Lipemia/Turbidity Indices as Indicators of Interference in Clinical Laboratory Analysis; Approved Guideline. CLSI document C56-A. Wayne, PA: Clinical and Laboratory Standards Institute; 2012 
• CLSI Collection, Transport and Processing of Blood Specimens for Testing Plasma-based Coagulation Assays and Molecular Hemostasis Assays; Approved Guideline – Fifth Edition. CLSI Document H21-A5; Wayne, PA: Clinical and Laboratory Standards Institute; 2008

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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals  

In today’s episode, with Lydie Nicoud, Director of Design and Biological Applications development, Cécile Hourquet and Audrey Carlo will try to better understand sensitivity and specificity of a diagnostic test, through some examples. 

Sources:  

• CLSI, Quantitative D-dimer for the Exclusion of Venous Thromboembolic Disease, CLSI document H59-A, Wayne PA; Clinical Laboratory Standards Institute 2011 
• Valentine Minet, Jean-Michel Dogné, and François Mullier, Functional Assays in the Diagnosis of Heparin-Induced Thrombocytopenia: A Review Molecules 22, no. 4 (April 11, 2017): 617, https://doi.org/10.3390/molecules22040617.
•  Cuker A, Arepally GM, Chong BH, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia. Blood Adv. 2018;2(22):3360-3392. doi:10.1182/bloodadvances.2018024489 
•  Nagler M, Bachmann LM , ten Cate H, ten Cate-Hoek A, Diagnostic value of immunoassays for heparin-induced thrombocytopenia: a systematic review and meta-analysis. Blood 2016; 127 (5): 546–557. doi: https://doi.org/10.1182/blood-2015-07-661215

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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals.  

In today’s episode, we will provide you our best tips and tricks to calculate the mean normal prothrombin time for INR assay.  To do so, Cécile Hourquet and Audrey Carlo are pleased to welcome Arnaud Rouvière, Manager of the International Application Engineer team of Stago.  

Source:  WHO technical report series ; no. 979, 2013 

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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, the Podcast providing expert answers to your expert questions.  

In today’s episode, our cybersecurity referent Alexandre Rousseaux will explain us how cybersecurity is impacting lab practices every day and why we are all talking about it. 

Follow us on LinkedIn In or Twitter

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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. 

Today episodes are broadcasted from October 13, which is the World Thrombosis Day. Our episodes are thus dedicated to raise awareness about thrombosis symptoms and management, through the interview of 3 “thrombosis survivors”: Debra Bryant, honorable mention recipient of the WTD 2020 Ambassador of the Year Award, Todd Robertson, one of the most active WTD Ambassadors within the US, and Chris Pugh, who lives in the UK and very recently started his "living with a clot" journey.

Get involved in the WTD movement 
Follow us on LinkedIn In or Twitter
 

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. 

Today episodes are broadcasted from October 13, which is the World Thrombosis Day. Our episodes are thus dedicated to raise awareness about thrombosis symptoms and management, through the interview of 3 “thrombosis survivors”: Debra Bryant, honorable mention recipient of the WTD 2020 Ambassador of the Year Award, Todd Robertson, one of the most active WTD Ambassadors within the US, and Chris Pugh, who lives in the UK and very recently started his "living with a clot" journey.

Get involved in the WTD movement
Follow us on LinkedIn In or Twitter

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. 

Today episodes are broadcasted from October 13, which is the World Thrombosis Day. Our episodes are thus dedicated to raise awareness about thrombosis symptoms and management, through the interview of 3 “thrombosis survivors”: Debra Bryant, honorable mention recipient of the WTD 2020 Ambassador of the Year Award, Todd Robertson, one of the most active WTD Ambassadors within the US, and Chris Pugh, who lives in the UK and very recently started his "living with a clot" journey.

Get involved in the WTD movement https://www.worldthrombosisday.org/
Follow us on LinkedIn In or Twitter
Lear more about Debra online patient group

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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, the Podcast providing expert answers to your expert questions. 
In today’s episode, with François Depasse our Clinical Development Director, we will discuss the selection of a cut-off for D-dimer assay in venous thromboembolism exclusion diagnosis. 

Sources:  Pernod G, Maignan M, Marlu R. Questioning the use of an age-adjusted D-dimer threshold to exclude venous thromboembolism: analysis of individual patient data from two diagnostic studies: comment. J Thromb Haemost 2016; 14: 2553–4.
Stavros V Konstantinides, Guy Meyer, Cecilia Becattini, Héctor Bueno, Geert-Jan Geersing, Veli-Pekka Harjola, Menno V Huisman, Marc Humbert, Catriona Sian Jennings, David Jiménez, Nils Kucher, Irene Marthe Lang, Mareike Lankeit, Roberto Lorusso, Lucia Mazzolai, Nicolas Meneveau, Fionnuala Ní Áinle, Paolo Prandoni, Piotr Pruszczyk, Marc Righini, Adam Torbicki, Eric Van Belle, José Luis Zamorano, ESC Scientific Document Group, 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC), European Heart Journal, Volume 41, Issue 4, 21 January 2020, Pages 543–603, https://doi.org/10.1093/eurheartj/ehz405.

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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, the Podcast providing expert answers to your expert questions. 
In today’s episode, thanks Minh-Lan Nguyen, product line manager, we will help you to differentiate and understand the goal of the externalized internal quality control (eIQC) and external quality assessment programs (EQA).

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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.