In this episode, Amy trades medical jargon for construction metaphors as she takes us on a journey through hemostasis, the body’s natural way of stopping a bleed. But what happens when the repair crew is understaffed—or missing entirely? That’s where factor replacement therapy comes in. Amy and our experts explain how it works, why timing matters, and how it helps people with bleeding disorders live safer, fuller lives. Whether you're new to the community or a longtime listener, you'll walk away with a better understanding of how the body works—and why treatment makes such a big difference.

Presenting Sponsor:

Presented by Sanofi

#MyHemophiliaTruth. Real stories. Powered by Sanofi. It’s time to consider the whole experience when it comes to managing hemophilia and change the conversation. Explore the full story at www.myhemophiliatruth.com

The Bigger Picture in Hemophilia B: 

Hemophilia A and hemophilia B are different bleeding disorders with unique pathologies and clinical features.1 Due to the distinct behavior of factor IX, multiple PK parameters should be considered when assessing bleed prevention. Learn how a broader view of PK may influence evaluation of treatment and management for patients with hemophilia B.2,3 Learn more at thebiggerpictureinhemb.com 

1. Castaman G, Matino D. Haematologica. 2019;104(9):1702-1709.

2. Dolan G, Benson G, Duffy A, et al. Blood Rev. 2018;32(1):52-60. 

3. Mann DM, Stafford KA, Poon M-C, Matino D, Stafford DW. Haemophilia. 2021;27(3):332-339.

Show Notes:

Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.

Presented by Sanofi

Subscribe to the Ask the Expert

 Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community? 

→ BloodStreamMedia.com

→ BloodStream Media on Facebook 

→ BloodStream Media on Instagram 

→ BloodStream Media on LinkedIn

On this exciting episode of Ask the Expert, join Amy as we delve into the fascinating world of blood clotting and anticoagulant therapy. We'll explore the clotting process with fun and relatable party analogies, featuring expert insights from Dr. Ben and Dr. Patrick. Discover how vital components like Protein C, Protein S, antithrombin, and TFPI work together to maintain the body's delicate clotting balance, and learn about the latest advancements in hemophilia treatment in this engaging and educational deep dive!

Presenting Sponsor:

Presented by Sanofi

#MyHemophiliaTruth. Real stories. Powered by Sanofi. It’s time to consider the whole experience when it comes to managing hemophilia and change the conversation. Explore the full story at www.myhemophiliatruth.com

Mark’s Story Join Mark as he shares about his experience living with hemophilia, including the impact it had on building and maintaining relationships throughout grade school, college, dating, and raising his family. Mark also highlights how shared decision making with his healthcare providers, and strong family and caregiver support in those decisions, can make all the difference when it comes to managing the daily challenges of hemophilia. Click here to watch his story: https://www.youtube.com/watch?v=tQ8oeM0zL24&list=PLmqBxf22n4lPMpAfLe4yv8haC6Ejcp1XL&index=8

Show Notes:

Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.

Presented by Sanofi

 Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community? 

→ BloodStreamMedia.com

→ BloodStream Media on Facebook 

→ BloodStream Media on Instagram 

→ BloodStream Media on LinkedIn

Dive into the crucial roles of Factor VIII, Factor IX, and thrombin in the blood clotting process. Hosts Amy and Patrick introduce expert Dr. Benjamin J. Samelson-Jones to discuss the interplay between these factors, including how they activate each other and form clots. Featuring insights from Dr. Mark Reding on the myriad functions of thrombin, this episode breaks down complex biochemical processes into easily digestible information for all listeners. Perfect for anyone looking to understand hemostasis and thrombosis better.

Presenting Sponsor:

Presented by Sanofi

Show Notes:

Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.

Presented by Sanofi

Subscribe to the Ask the Expert

 Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community? 

→ BloodStreamMedia.com

→ BloodStream Media on Facebook 

→ BloodStream Media on Instagram 

→ BloodStream Media on LinkedIn

This episode of "Ask the Expert" titled "Striking the Right Balance – Why Does it Matter in Hemophilia Treatment?" delves into the concept of rebalancing in hemophilia treatment. Hosted by Amy Bord, the episode features expert insights from Dr. Ben Samuelson Jones, Dr. Patrick Ellsworth, and Dr. Mark Redding. They explain how hemophilia treatments can go beyond merely replacing missing clotting factors by using rebalancing agents that adjust anticoagulant proteins. The conversation emphasizes the importance of understanding the delicate balance between bleeding and clotting in the body, why this knowledge is vital for treatment decisions, and introduces the new class of medications called rebalancing agents. The episode also highlights the role of individual bleeding tendencies in determining appropriate treatments.

Presenting Sponsor:

Presented by Sanofi

Show Notes:

Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.

Presented by Sanofi

Subscribe to the Ask the Expert

 Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community? 

→ BloodStreamMedia.com

→ BloodStream Media on Facebook 

→ BloodStream Media on Instagram 

→ BloodStream Media on LinkedIn

In this episode of 'Ask the Expert,' host Amy Board dives into the clotting cascade and explains how our blood clots. Alongside experts Dr. Ben Samuelson Jones, Dr. Amy Dunn, Dr. Mark Redding, and Dr. Patrick Ellsworth, Amy unpacks the complexity of the hemostatic system, discusses new treatments for hemophilia, and explores both the clotting and regulating parts of this vital bodily function. Tune in to understand how the clotting system works and the exciting potential of new therapies in the field.

Presenting Sponsor:

Presented by Sanofi

Show Notes:

Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.

Presented by Sanofi

Subscribe to the Ask the Expert

 Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community? 

→ BloodStreamMedia.com

→ BloodStream Media on Facebook 

→ BloodStream Media on Instagram 

→ BloodStream Media on LinkedIn

Ask the Expert is back with a twelve-episode deep dive into the evolving landscape of a groundbreaking new class of therapies in hemophilia treatment—rebalancing agents. Through expert insights and discussions, our new season, Hemophilia: On Balance, unpacks complex science to make it accessible and relevant to the hemophilia community. Episodes will be released monthly starting March 2025, with bonus content dropping weekly. Whether you’re a patient, caregiver, or healthcare provider, Ask the Expert empowers you to understand the latest advances and make informed decisions about hemophilia care.

Presenting Sponsor:

Presented by Sanofi

Show Notes:

Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.

Presented by Sanofi

Subscribe to the Ask the Expert

 Did you know BloodStreamMedia.com is your one-stop shop for all podcasts for the bleeding disorders and rare disease community? 

→ BloodStreamMedia.com

→ BloodStream Media on Facebook 

→ BloodStream Media on Instagram 

→ BloodStream Media on LinkedIn

Our guest for this month is Believe Limited CEO and Bloodstream host, Patrick James Lynch. Ask the Expert is headed in a new direction and Patrick joins us to share what the future will hold for the Bloodstream Media network. Even though this will be the final episode of Ask the Expert, we are excited to announce the new path for our expert interviews, because they’re not going away! Listen in with Patrick and Amy as they share the new and exciting things coming from Bloodstream Media!

Welcome to Episode 40, or To the Future! The final episode of the Ask The Expert Podcast! 

Check out all the podcast offerings from Bloodstream Media: https://www.bloodstreammedia.com/

Register for the virtual Bleeding Disorder Conference here: https://events.hemophilia.org/ehome/bleedingdisordersconference/about/?&_ga=2.12224756.1785968952.1589565712-1855623951.1578586058

Join us for our “Get to Know the Expert” episode of Ask the Expert! Having the opportunity to know our national leaders in a personal way is an honor and a treat for any community. Join us on today’s episode to get to know CEO the National Hemophilia Foundation, Dr. Len Valentino! We’ll learn how Dr. Valentino got his start, what lessons he learned from treating patients, his interests in the global disparity of care, and his thoughts of the Michael Jordan documentary, The Last Dance! Join us to get to know Dr. Valentino a little better!

Welcome to Episode 39 - or our Get to Know the Expert Episode - of the Ask The Expert Podcast! 

Check out the weekly webinar series provided by the National Hemophilia Foundation here:

The National Hemophilia Foundation: https://www.hemophilia.org/

Register for the virtual Bleeding Disorder Conference here: https://events.hemophilia.org/ehome/bleedingdisordersconference/about/?&_ga=2.12224756.1785968952.1589565712-1855623951.1578586058

The National Hemophilia Foundation announced new leadership in Dr. Len Valentino weeks before the COVID-19 outbreak and his unique position to guide our community during this unprecedented time has been welcome. Dr. Valentino joins us on Ask the Expert this month to share a bit of his story and his thoughts on the pandemic could affect the bleeding disorder community. Dr. Valentino shares how NHF is addressing the current COVID pandemic, NHF’s national research agenda, and how COVID could impact the shift in treatment in hemophilia. We’ll also chat about the Bleeding Disorder Conference going virtual this year, so join us for a can’t miss episode of Ask the Expert!

Welcome to Episode 39 - or our Dr. Valentino Episode - of the Ask The Expert Podcast! 

Check out the weekly webinar series provided by the National Hemophilia Foundation here:

The National Hemophilia Foundation: https://www.hemophilia.org/

Register for the virtual Bleeding Disorder Conference here: https://events.hemophilia.org/ehome/bleedingdisordersconference/about/?&_ga=2.12224756.1785968952.1589565712-1855623951.1578586058

Join us for our “Get to Know the Expert” episode of Ask the Expert! Having the opportunity to know our national leaders in a personal way is an honor and a treat for any community. Join us on today’s episode to get to know CEO of Hemophilia Federation of America (HFA), Sharon Meyers, as she begins her tenure at the organization. Sharon shares how she became involved in non-profit work, her passion and philosophy on fundraising, and how she became involved within the bleeding disorder community! Join us to hear more about Sharon’s personal journey and what makes her tick! A fun episode of Ask the Expert!

Welcome to Episode 38 - or our Get to Know the Expert Episode - of the Ask The Expert Podcast! 

Check out the terrific resources from the Hemophilia Federation of America in the midst of COVID-19 outbreak:

Hemophilia Federation of America: https://www.hemophiliafed.org/

HFA COVID-19 Resources Page: https://www.hemophiliafed.org/news-stories/2020/04/coronavirus-covid-19-what-hfa-is-doing/

HFA COVID-19 Relief Fund: https://www.hemophiliafed.org/our-role-and-programs/assisting-and-advocating/financial-assistance/covid-19-relief-fund/

HFA Helping Hands Financial Assistance Program: https://www.hemophiliafed.org/our-role-and-programs/assisting-and-advocating/financial-assistance/helping-hands-emergency-assistance/

NHF Informational Webinars during COVID Crisis: https://www.hemophilia.org/