In this special episode of The EP Edit podcast, Randall Lee, MD, talks with Kenneth Ellenbogen, MD, FHRS, and Hugh Calkins, MD, about the role of atrial fibrillation (AF) ablation in patients with heart failure, including recent clinical trials, new technologies, and the role of hybrid therapies. Randall Lee, MD, is an electrophysiologist at UCSF Health and the Chief Medical Officer of AtriCure, Inc. Kenneth Ellenbogen, MD, FHRS, is a Professor of Medicine and Chair of the Division of Cardiology at the Virginia Commonwealth University (VCU) School of Medicine in Richmond, Virginia. Hugh Calkins, MD, is a Professor of Medicine and Director of the Electrophysiology Laboratory and Arrhythmia Service at the Johns Hopkins Hospital in Baltimore, Maryland.