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Authentic Biochemistry
Authentic Biochemistry episodes
- AMPK and Immuno-Epigenetic Biochemistry Part 2/2/ DJGPhD. Authentic Biochemistry 27.12.21
J Neuroinflammation. 2019; 16: 34
Nature Cell Biology, 02 Sep 2011, 13(9):1016-1023
Critical Reviews in Clinical Laboratory Sciences Volume 56, 2019 - Issue 7 Pages 472-492
30 min - AMPK and Immuno-Epigenetic Biochemistry Part 1. Dr. Daniel J. Guerra. 27.12.21. Authentic Biochemistry
References
Nat Cell Biol. 2019 Mar; 21(3): 397–407
CELL Volume 126, Issue 3, 11 August 2006, Pages 503-514
Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55
Int J Biol Sci. 2015; 11(11): 1272–1280
Sci Signal. 2017 Jan 31; 10(464): eaaf7478.
Front Immunol. 2019; 10: 345.
J Neuroinflammation. 2019; 16: 34.
30 min - AMPK negatively regulates lipogenesis by phosphorylating ACCase 1&2 plus HMGCoA reductase thus supporting beta oxidation of fatty acids . Dr. Daniel J. Guerra. 22.12.21. Authentic Biochemistry
Cell Metabolism 2020 31472-492
Amino Acids. 2012 Oct;43(4):1803-7
Molecular Cell Volume 81, Issue 18, 16 September 2021, Pages 3677-3690
30 min - AMPK is associated with the POMC vs, NPY neuronal axis under Leptin Control. DJGPhD. 20.12.21 Authentic Biochemistry
References
HORMONES 2013, 12(2):172-191
Proc Natl Acad Sci U S A . 2002 Dec 24;99(26):17155-60
Eur J Endocrinol. 2017 176(5): R235–R246.
30 min - AMPK Allosteric Regulation and Interaction with the Opposing mTORC Network. Part 2. Dr. Daniel J. Guerra. Authentic Biochemistry 19.12.21
Eur J Endocrinol. 2017 176(5): R235–R246
Molecular Cell Volume 81, Issue 18, 16 September 2021, Pages 3677-3690
30 min - Bio-Molecular Regulator Series . AMPK. Part One. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast Production.19.12.21.
An introductory lecture on the biomolecular sensor kinase, Adenosyl Mono-Phosphate (protein) Kinase; AMPK.
References
Mol Genet Metab. 2013 Jul;109(3):260-8
PLoS One. 2016 Aug 16;11(8):e0161252.
Experimental & Molecular Medicine volume 48, 224 (2016)
Molecular Cell Volume 81, Issue 18, 16 September 2021, Pages 3677-3690
30 min - T-lymphocyte and macrophage membrane CD38 ecto-enzyme mediated NAD catabolism is associated with ageing and the decline in Sirtuin-mediated deacylase activity. DJGPhD.11.Dec.21' Authentic Biochemistry
References
Cell Metabolism. 2016. 23, 1127–1139
Cells 2020, 9(1), 228
Front. Immunol., 31 May 2019
Int J Mol Sci. 2020 Nov; 21(22): 8609
Circ Res. 2018 Sep 14; 123(7): 868–885.
Int J Mol Sci. 2019 Mar; 20(5): 1223
30 min - Synthesis of the sirtuin locus and NAD+ with T lymphocyte CD38 and the corruption over control on inflammation. DJGPhD. Authentic Biochemistry 10.Dec21. II
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Cells 2020, 9(1), 228
Circ Res. 2018 Sep 14; 123(7): 868–885
Front. Immunol., 31 May 2019
---Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/messageSupport this podcast: https://anchor.fm/dr-daniel-j-guerra/support30 min - Aposteriori synthesis of neuroendocrine linked clock chronicity and the Senescent associated Secretory Phenotype through the synthetic apriori lens of NAD+. DJGPhD.10Dec21. Authentic Biochemistry
References
Nat Cell Biol. 2019 Mar; 21(3): 397–407
J Diabetes Metab Disord. 2020 Jul 21;19(2):1797-1825
Int. J. Mol. Sci. 2014, 15, 16848-16884
30 min - How testosterone-aromatase derived estradiol transformation to 2-methoxy-17beta-estradiol can mitigate cell proliferation by promoting a senescent phenotype.DJGPhD. Authentic Biochemistry.8.DEC.21
Besides 2-methoxy-17beta-estradiol, cell cycle arrest via chromatin deacetylation can mitigate cell proliferation by decreasing global transcription while promoting the expression of tumor suppressor genes like p16INK4a while DNA Damage Repair (DDR) from pro-inflammatory cytokine production from senescent cells and Th1 lymphocytes can inhibit commitment to mitosis and cytokinesis by generating the paracrine SASP paradigm.
Refs.
Am J Physiol Cell Physiol 2012;302:C1026-C1034
Steroids Volume 75, Issue 10, October 2010, Pages 625-631
Oncotarget. 2013 Oct; 4(10): 1552–1553
Cancer Metastasis Rev. 2020; 39(3): 681–709
31 min
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.