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FAQs about Authentic Biochemistry:How many episodes does Authentic Biochemistry have?The podcast currently has 1,249 episodes available.
May 12, 2023ImmunoEpigenetics64. IDH1/2 ad Malic enzymes 1/2/3 may generate NADPH thus driving removal of ROS while simultaneously promoting atherosclerosis and tumorigenesis via epigenetic and bioenergetic meansReferencesFree Radical Biology and Medicine 2014. Volume 71, June.Pages 1-15J Mol Endocrinol. 2020 Nov; 65(4): R77–R90. REDOX and Cholesterol metabolism lectures-Dr Guerra...more30minPlay
May 10, 2023ImmunoEpigenetics63. Amino acid metabolism is linked to DNA methylation via glycolytic intermediates and redox poise to expose neomorphic /antimorphic IDH1/2 transformation generating oncometabolitesReferencesCancers (Basel). 2019 May; 11(5): 678. Oncogene.2017 Mar 23; 36(12): 1607–1618Dr Guerra's annotated lecture notes from graduate biochemistry course(s)...more30minPlay
May 10, 2023ImmunoEpigenetics62.Macrophage "training" and T cell activation are epigentically controlled by moonlighting glycolytic and amino acid metabolic enzymes generating enantiomers of 2-OH glutarate.DJGPhDReferencesFront. Cell Dev. Biol., 26 March2021 Sec. Molecular and Cellular Oncology Volume 9 Cancer Drug Resist 2020;3:762-74.Oncogene.2017 Mar 23; 36(12): 1607–1618Front Immunol. 2020; 11: 1782. ...more30minPlay
May 09, 2023ImmunoEpigenetics61. The role of leucocyte and lymphocyte aerobic glycolysis and bioenergetic trafficking between cytosol and the mitochondria mediating nuclear epigenetic substrate availability.ReferencesDr Guerra Intermediary metabolic lecture notes-graduate biochemistry lecture archivesEpigenetics. 2019; 14(12): 1183–1193. Drug Discov Today. 2017 Jan; 22(1): 186–193. ...more30minPlay
May 07, 2023Immunoepigenetics 60. LOH of PHLDA3 confers wt allelic methylation and loss of activity in pancreatic neuroendocrine tumorigenesis. DJGPhD.7May23 Authentic Biochemistry PodcastReferencesInt J Mol Sci. 2020 Jun; 21(11): 4098. ...more30minPlay
May 06, 2023ImmunoEpigenetics59. The P53/AKT/PHLDA3 axis over tumorigenicity is controlled by endomembraneous targeting via glycerol lipid PhosphatidylInositol bis-phosphate (PIP2) phosphorylation to PIP3.5.12.23ReferencesInt J Mol Sci. 2020 Jun; 21(11): 4098. Authentic Biochemistry lectures :ImmunoEpigenetics 56-58 ...more30minPlay
April 28, 2023ImmunoEpigenetics 58. Epigenetic mechanisms role in Loss of Heterozygosity (LOH) in TSG's advancing targeting of solid tumors via pharmacotherapeutic CAR-T cells. DJGPhD 27.4.23. Authentic Biochem.ReferencesBMC Medical Genomics. 2015. volume 8, Article number 45.Journal for ImmunoTherapy of Cancer 2022;10:e003826....more30minPlay
April 21, 2023ImmunoEpigenetics 57. Plasmacytoid dendritic cell neoplasias and the CAR-T cell tumor microenvironment exposure altering epigenetic TF regulation leading to diverse differentiation. DJGPhD.20.4.23ReferencesCurrent Oncology Reports. 2020. 1534-6269, May 15, Vol. 22, Issue 6.Cell. 2021 Dec 9; 184(25):6081–6100.e26. ...more30minPlay
April 15, 2023ImmunoEpigenetics 56. Dendritic cell immunobiochemistry introductions. DJGPhD. Authentic Biochemistry 15.4.23ReferencesAutoimmunity. 2012 Aug;45(5):333-47Clinical and Experimental Rheumatology 2019: One year in review 2019: systemic lupus erythematosus Trends in Immunology, 2021-01-01, Volume 42, Issue 1, Pages 59-75Annu. Rev. Immunol. 2000. 18:767–811...more29minPlay
April 14, 2023ImmunoEpigenetics55. ILC and Treg differentiation is mediated by acetylation and methylation epigenegtic authorship at discrete TF binding site domains.DJGPhD.14.4.23. Authentic BiochemistryReferencesCell Reports 2015 10, 2043-2054DOIID2_HUMAN,Q02363Experimental & Molecular Medicine 2019. volume 51, Article number: 80....more29minPlay
FAQs about Authentic Biochemistry:How many episodes does Authentic Biochemistry have?The podcast currently has 1,249 episodes available.