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Authentic Biochemistry
Authentic Biochemistry episodes
- BioMedical Portrait I. 13b. 25 hydroxy cholesterol controling SREBP is linked toinflammation and the regulation of potentiating estrogen mediation over AD in post menapausal women.DJGPHD.18.8.23
References
Immunity 2021. 54, 2273–2287
Front Immunol. 2020. 11: 784
30 min - Biomedical Portrait I, 13. Receptor boud 17Beta-estradiol may overturn the the failure to synthesize cholesterol in CNS caveolae thus blocking release of Beta-secretase to generate A-beta from APP.
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[Mol Neurobiol] 2020 Jun; Vol. 57 (6), pp. 2654-2670
Oncol Rep. 2023 May;49(5):93
30 min - BioMedical Portraits I. Chapter 12. Unique lipoprotein lipase mediated lipid alteration of endothelial cell function in the mammalian CNS may traffick in oxysterol binding protein linked PM-female AD
References
Steroids. 2022 Sep;185:109053
Trends Neurosci. 2015 Jun; 38(6): 364–374
Progress in Molecular Biology and Translational Science
Volume 168.Pages 257-275Histol Histopathol. 2018 Jan; 33(1): 1–10.
30 min - BioMedical Portraits I. [11]. Phospholipid and lipoprotein lipase activity may link to oxy-cholesterol/PL transport mechanisms to generate post-menopausal AD. DJGPhD.16.8.23. Authentic Biochemistry
References
Histol Histopathol. 2018 Jan; 33(1): 1–10
J Steroid Biochem Mol Biol. 2022Feb;216:106040
Steroids. 2022 Sep;185:109053
30 min - BioMedical PortraitI-10. Sterol binding protein and oxysterols regulate membrane fusion and trafficking obtaining a complex landscape for post menopausal estrogen assoc. neurodegeneration.DJGPhD.
References
J Steroid Biochem Mol Biol. 2022. Feb;216:106040.
Steroids. 2022 Sep;185:109053
30 min - BioMedical PortraitsI.9. The 27-hydroxychol association with estrogen receptors and LXR provide contrarion associations with female AD and immune-controlled bacterial pathophysiology.DJGPhD.14.8.23
References
Alzheimer's Research & Therapy 2021. volume13, Article number: 56.
Progress in Molecular Biology and Translational Science 2019. Volume 168 #
29 min - BioMedical Portrait I. Chapter 8. Female AD progression post-menopausal severity is a complex pathobiochemical event that may involve cholesterol and steroid metabolism in the CNS and periphery.DJGPhD
References
Genes & Immunity 2021 volume 22, pages 125–140
Arch Endocrinol Metab. 2022 Jan-Feb; 66(1): 77–87
Essays Biochem. 2021 Nov; 65(6): 913–925
30 min - BioMedical Portraits I. Chapter 7. Hormone replacement and the general distinctions of cholesterol homeostasis, metabolic zonation, hydroxysterols and estrogen receptor heterogeneity in female AD.
Reference
Journal of Cognitive Neuroscience (2022)34 (8): 1500–1520
30 min - BioMedical Portraits I. Chapter 6. Complications of female cerebrovascular trauma and obesity-linked Type2 Diabetes in post-menopausal estrogen therapeutics for prophylactic treatment of subsequent AD
References
Mol Neurobiol 2020 Jun; Vol. 57 (6), pp. 2654-2670
Brain Res. 2009 Sep 22; 1290: 1–11.
JAMA.2003;289(20):2651-2662.
30 min - Biomedical Portraits I. Part 5. 17-beta estradiol monotherapy in post-menopausal women has no irrefutable therapeutic benefit for treating cognitive decline in early AD dementia.DJGPhD.8AUG23.AB.
References
JAMA.2003;289(20):2651-2662.
Essays Biochem. 2021 Nov; 65(6): 913–925
Biol Psychiatry. 2019 Sep 15;86(6):421-432
30 min
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.