In this episode, we explore the connections between Autism and Parkinson's, focusing particularly on the basal ganglia and its substructures, notably the substantia nigra within the midbrain. We discuss how the substantia nigra, known for its high concentration of neuromelanin, plays a critical role in these disorders. The episode examines how neuromelanin, a dark pigment, not only absorbs all frequencies of light but also has antioxidant properties, binds metals, and acts as a neuroprotector. This discussion leads into the broader implications of environmental signals, particularly light, on human biology, touching on how modern changes in light exposure might affect these conditions.

We examine the role of tyrosine in the synthesis of neuromelanin and its derivatives like dopamine, which are crucial for neural function. We look at how deficiencies or imbalances in these pathways could lead to the symptoms observed in Autism and Parkinson's, including motor function issues. The conversation also covers the direct and indirect pathways in the basal ganglia, explaining how these pathways facilitate or inhibit movement, respectively, and how their dysfunction can manifest in the characteristic motor symptoms of both disorders. We also touch on the significance of thyroid function, particularly the roles of T3 and T4 hormones, in brain development and neuron health, tying these elements back to the overarching theme of energy loss and transduction in both Autism and Parkinson's.

Autism and Parkinson's are a lack of, or a loss of, energy.

Biological Energy: Quantum Mechanisms, Water, DHA, and NF-kB: https://youtu.be/2-IA_gunXbw

Tree comparison https://youtube.com/shorts/cLu53oVRRjI

0:00 Autism and Parkinson's; Basal Ganglia; Substantia Nigra; Neuromelanin; Internal Calculators

2:15 Tyrosine; Chromophores; Aromatic Amino Acids

3:50 Biological Energy; Mitochondria; Environmental Signals; Cytochrome C Oxidase; Autism Research Miss

6:20 Deep Brain Stimulation

6:48 Neuromelanin

9:02 Reverse Engineer ATPase

10:48 Tree Examples

11:45 Hypoxia and loss of energy & dopamine

12:26 Eyes, hair, & skin; RPE; efficiency & power; What is Light?

13:58 Light; Information & Energy; electromagnetic; wave-particle duality; sunlight versus artificial light

17:08 Thyroid; T3 & T4; Iodine

18:31 Roles of T3

23:00 Loss of energy in the womb & Autism research

25:00 Melanin + Water = Electrons

26:40 Basal Ganglia; "Motivations" & Movements; Direct Pathway

30:55 Indirect Pathway

32:52 Go, No-Go; Action selection, learning & habits; fine motor skills

34:18 Parkinson's and loss of timing & energy; modulating the two pathways & dopamine

37:07 Reviews/Ratings & contact info

X: https://x.com/rps47586

Hopp: https://www.hopp.bio/fromthespectrum

YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA

TikTok: (I don't love it) https://www.tiktok.com/@fromthespectrumpodcast

email: [email protected]