BacterioFiles

BacterioFiles 360 - Fellow Phages Fight Fortifications


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This episode: Bacteriophages with defenses against bacterial CRISPR defenses have to work together to succeed!

Thanks to Drs. Edze Westra and Stineke van Houte for their contributions, and to Calvin Cornell for suggesting this story!

Download Episode (9.6 MB, 10.5 minutes)

Show notes:
Microbe of the episode: Lactobacillus casei subsp. alactosus

News item 1/News item 2

Journal Papers:
Borges AL, Zhang JY, Rollins MF, Osuna BA, Wiedenheft B, Bondy-Denomy J. 2018. Bacteriophage Cooperation Suppresses CRISPR-Cas3 and Cas9 Immunity. Cell 174:917-925.e10.

Landsberger M, Gandon S, Meaden S, Rollie C, Chevallereau A, Chabas H, Buckling A, Westra ER, Houte S van. 2018. Anti-CRISPR Phages Cooperate to Overcome CRISPR-Cas Immunity. Cell 174:908-916.e12.

Other interesting stories:

  • Aphids can see fluorescence from pathogenic bacteria to avoid them on leaves
  • Fecal transplants from yourself before antibiotics could restore gut community after antibiotics
  • Engineering E. coli to convert CO2 and methanol into useful products (paper)
  • Used panel of bioluminescent bacteria to test artificial sweetener toxicity

 

Email questions or comments to bacteriofiles at gmail dot com. Thanks for listening!

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BacterioFilesBy Jesse Noar

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