By Vincent Racaniello
4.9
443443 ratings
The podcast currently has 247 episodes available.
TWiP solves the case of the Manhattan man with pain on urination or ejaculation, and presents a new case for you to solve.
Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula
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Links for this episodeA middle-aged male is referred to evaluation because of eosinophilia. This man is married, living here in the NY tristate area, and this was picked up on ‘routine blood work’ by his primary care doctor. This man had been in the military, serving as a marine, with time spent in Okinawa, Japan. This individual does report sexual activity with paid sex workers while in Okinawa but has been monogamous with his current wife for many years. A number of investigations are done with a test coming back showing serological evidence of a prior parasitic infection and he was treated with an antiparasitic medicine with resolution of the eosinophilia. The eosinophilia returned and he was referred to us. Blood work is now down showing evidence of a viral infection that might explain why the eosinophilia returned after treatment. Pt is HIV negative. This was prior to the COVID-19 pandemic. He is on no medications and in general feels fine.
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Music by Ronald Jenkees
TWiP taps into Dickson’s knowledge of Trichinella to discuss an outbreak in humans who consumed rare bear meat, and the impact of globalization and climate change on the epidemiology of the species.
Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin
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Music by Ronald Jenkees
Founder of Floating Doctors Ben LaBrot joins TWiP to solve the case of the 1 year old in northeastern Panama with a fatal leg infection, followed by a discussion of the history and mission of Floating Doctors.
Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula
Guest: Ben LaBrot
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Links for this episodeA man in his early 20s comes in reporting pain when he urinates or ejaculates. He reports that he is sexually active. He does confide that he has been in a relationship with a woman but he had a sexual encounter outside this relationship about 2 weeks ago when they were on a break and he did not wear protection. He feels like he needs to urinate more often and describes thin white discharge from the penis. He reports that he has no history of any sexually transmitted infections and had no medical issues prior to this.
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Music by Ronald Jenkees
Lilach Sheiner joins TWiP to talk about her career and her work on engineering Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons.
Hosts: Vincent Racaniello, Dickson Despommier, and Christina Naula
Guest: Lilach Sheiner
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Music by Ronald Jenkees
TWiP solves the case of the Woman with White Worms, and submits a new case involving a 1 year old in northeastern Panama with a fatal leg infection.
Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula
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Links for this episodeThis case comes from Panama mid summer 2024. A provider for Floating Doctors working in the coastal region in northeastern Panama. This case involves a one year old, so the history is a bit difficult, but there may have initially been a scratch or some sort of break in the skin. Otherwise healthy but over a period of time this area expands and becomes a deep necrotic wound on the leg. Several other nearby wounds develop and become deep and infected. By the time this one year old is seen by the provider much of the leg appears eaten away. This is just the tip of the iceberg as a number of others develop similar wounds in the area. No prior medical history.
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Music by Ronald Jenkees
TWiP reviews a study showing that intestinal helminth infection impairs vaccine-induced T cell responses through an IL-10 pathway, which compromised protection against antigenically drifted SARS-CoV-2 variants.
Hosts: Vincent Racaniello, Daniel Griffin and Christina Naula
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Music by Ronald Jenkees
Sean Murphy joins TWiP to discuss his career and the work of his laboratory to assess the daily natural history of asymptomatic Plasmodium infections in adults and older children in Katakwi, Uganda.
Hosts: Vincent Racaniello, Dickson Despommier and Christina Naula
Guest: Sean Murphy
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Music by Ronald Jenkees
TWiP solves the case of the AIDS patient who developed fever and watery diarrhea after drinking NYC tap water, and present a new case for your sleuthing.
Hosts: Vincent Racaniello and Daniel Griffin
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New Case
Man in his 70s originally from Mainland China, then Hong Kong who has been living in the US for decades is admitted to the hospital with fever for 6 days. He reports that he saw his primary care physician in Queens and was referred to the hospital after blood work revealed a sodium level of 123 and an increased monocyte count. Pt reports drenching sweats, lots of outdoor activity walking in local parks in Queens. He reports he does not feel particularly sick. PMH-HTN, BPH PSH-neg Social-retired, no wife, has one son, no pets, no exotic exposures or recent travel VS febrile to 39.5, tachycardia, meets sepsis criteria PE -unremarkable Labs, nl wbc, eos-0, elevated neutrophils and monocytes, Na-123, elevated AST, elevated ALT, low platelets, low Hct, CT Chest A/P unremarkable
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Music by Ronald Jenkees
Michael Barrett joins TWiP to discuss progress in the elimination of human African trypanosomiasis caused by Trypanosoma brucei gambiense.
Hosts: Daniel Griffin, Dickson Despommier and Christina Naula
Guest: Michael Barrett
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Links for this episodeBecome a patron of TWiP
Send your guesses to [email protected] with TWiP 237 in the subject line
Send your questions and comments to [email protected]
Music by Ronald Jenkees
The podcast currently has 247 episodes available.
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