Could the secret to deeper, more restorative sleep be as simple as the right light… at the right time? Dr. Jay Khorsandi unpacks the cutting-edge science of red light therapy, how it interacts with your body’s natural melatonin production, and why timing is everything. Learn the powerful connection between light exposure, circadian rhythm, and hormone regulation… and discover why most people are sabotaging their sleep with one common mistake. Plus… practical, step-by-step strategies to use light like a biohacker and wake up feeling truly recharged.

Support the show

Discover the shocking connection between your oral health and sleep quality that 90% of people don't know about. Dr. Jay Khorsandi reveals how teeth grinding, gum disease, tongue position, and even your bite alignment could be sabotaging your sleep every single night. Learn the hidden signs your mouth is destroying your rest and the simple dental interventions that could transform your sleep forever.

Support the show

In this episode of Best Night Ever, Dr. Jay Khorsandi reveals how your sleep position affects everything from sleep apnea to brain detoxification. Discover why side sleeping isn't just more comfortable—it's scientifically proven to enhance brain cleaning, reduce breathing disruptions, and optimize recovery. Learn the surprising differences between left and right side sleeping, plus get actionable strategies for better spine health and deeper sleep.

Support the show

In this episode of Best Night Ever, Dr. Jay Khorsandi dives deep into the science—and art—of napping. From ancient traditions to cutting-edge studies, you’ll learn why short naps aren’t just a guilty pleasure—they’re one of the most underutilized tools for cognitive performance, emotional balance, and even anti-aging.

Discover the ideal nap duration for memory, mood, and physical recovery. Learn about advanced hacks like the coffee nap, pink noise, and wearable tech for optimizing your HRV. Plus, hear how global cultures like Spain, Japan, and China have long embraced the midday snooze—and what modern chronobiology has to say about it.

If you’re ready to level up your energy, focus, and longevity—this episode is your 20-minute wake-up call.

Support the show

Are your sleep supplements actually helping — or just expensive hype? In this episode of Best Night Ever, Dr. Jay Khorsandi (@sleepbiohacker) cuts through the noise and breaks down the most effective, science-backed supplements for deep, restorative sleep. From magnesium and glycine to L-theanine, apigenin, and bonus compounds like tart cherry and ashwagandha, you’ll learn what to take, when to take it, and how to track what works. Plus, Dr. Jay shares his personal nighttime stack, key research insights, and practical tips to optimize your sleep without the guesswork.

Support the show

In this episode of Best Night Ever, we go far beyond the basics of sleep hygiene and unlock the science-backed secrets to transform your nights — and your days. Join Dr. Jay Khorsandi as we break down the three most potent levers for better sleep: light exposure, body temperature, and circadian rhythm alignment.

You’ll get practical hacks, advanced tools, and the latest research on:
 ☀️ Using morning sunlight and evening dimming to reset your internal clock
 ❄️ Optimizing bedroom temperature for deeper sleep
 ⏰ Anchoring your body’s circadian rhythm for peak energy, mood, and health

Plus, we cover smart tech, supplements, and a gold-standard wind-down routine you can start tonight. Whether you’re a biohacker or just tired of feeling exhausted, this episode will equip you with everything you need to wake up refreshed.

👉 Follow @sleepbiohacker on Instagram for daily tips, and don’t forget to share this episode with a friend!

Support the show

And be sure to connect with me on ig here https://www.instagram.com/sleepbiohacker/?hl=en
And check out other resources here https://www.sleepbiohacker.com/

Connect with Barton https://www.instagram.com/askbarton/channel/

Follow Upgraded Formulas https://www.instagram.com/upgradedformulas/

Get your new favorite minerals here https://www.upgradedformulas.com/

And use code: DRJAY for 20% off

2:48 How groundwater that was missing lithium, and was directly correlated to the highest rates of suicide and depression in the country.

3:34 Upgrading Mood

4:20 Can you get all of your minerals through food?

4:35 ​​What is the difference between vitamins minerals, electrolytes?

6:00 People that go back to prison again and again and again, have really high levels of certain things.

6:35 Is taking 50-100 supplements actually a brag?

6:55 Why you need to “test, not guess”

7:53 “If your calcium level is way up here, you should actually stop, stop taking the holy grail of vitamin D that everyone says is so good”

8:23 “Our bodies are a multi-dimensional piano where you play one key and there's a ripple effect.”

10:20 The power of alignment and WHY Barton started Upgraded Formulas

12:05 So what test should I start with?

12:40 Periodic Law & why test hair 

16:48 Vitamins were useless unless you had minerals there to activate them.

16:55 Vitamin D, if you don't have boron doesn't get activated.

17:22 If you already have low magnesium, eight out of 10 people are deficient in…

18:45 More on Barton’s why

20:05 Bone spurs and magnesium deficiency & body electric

23:30 Will raw liver do it? Or do I need to be taking minerals too?

24:40 Let's talk about copper and iron

Support the show

After 20 years as a regular dentist, Dr. Isabel thought that becoming a holistic and integrative dentist was necessary for the health and well-being of her patients. She got a Ph.D. in Integrative Medicine and studied biological dentistry and the nutritional and psycho-emotional connections between the mouth and the body. She is currently coaching her patients to find the root cause of their oral and whole-body imbalances.

She found that the body communicates through pain, symptoms, illnesses, emotions, and thoughts. She reached this conclusion after attempting to comprehend her and her patients' health issues. And chose to teach people through coaching, workshops, and retreats to be healthy and happy. She can identify the psycho-emotional blockage or limiting belief in your body and instruct you on how to discover it. Then, she assists you in learning them and creating new beliefs to obtain the health and life you deserve.

https://www.drisabelperez.com/

https://www.instagram.com/dr.isabelperez/

And be sure to connect with me on ig here https://www.instagram.com/sleepbiohacker/?hl=en

5:00 Ditching typical X-rays for full medical history and a CT scan, which is a 3d image.

10:00 How your DNA and grandparents DNA affects your dental health: Bio Dental Health

14:40 Do you get anxious at the dentist? Stem Office stimulates alpha brainwaves to help calm you down.

15:30 You can change how you look at past traumas 

16:38 TMJ & Emotions

21:00 Trauma Extractions

22:00 How not feeling enough could be affecting your dental health

25:10 Root Canals

29:42 Cavitations

32:43 Pineal Calcification

36:57 Mercury Amalgam Fillings and what you need to know about the removal process

39:15 How breathing through your mouth can hurt your oral health

40:00 Is it possible to have great oral hygiene, but have tooth decay issues?

44:32 Oil pulling 

45:00 “Once I look at the plaque that dental plaque under the microscope, I know exactly why they are having this inflammation.”

46:00 Alzheimer's and Spirochetes 

51:00 The power of mouth taping for Sleep Apnea

52:00 ADHD and alignment of the mouth

57:00 Brush with a soft electric toothbrush  

Support the show

For 10% OFF use code: bestnightever10
https://bioptimizers.com/

Follow BiOptimizers and myself on instagram
https://www.instagram.com/bioptimizers/
https://www.instagram.com/sleepbiohacker/

We talked about:

The power of enzymes and why we all need them!

Leaky gut 

The biggest health mistakes you may be making

How to optimize as you get older and actually feel better as you age! 

Of course, we talked about sleep! He spilled the secrets of his co-founder’s $50k sleep system!

Support the show

Could you use a little more help with stress reduction? I know I could. And you know, I'm always on the hunt for the coolest and most impactful technology to help you stress less and feel better. In this show, I'm sharing with you a new device in the world of stress reduction and better sleep, and it's called Cove. I get a lot of products and technologies to try people send them to me, a lot of them tend to get redundant or don't deliver. But this one stood out because the more I learned about it, and what it does, the more I got intrigued, and the more impact it had on my personal well-being. Now why this one works is because the Cove works on an entirely different brain pathway and one which you may have never heard of. I know I haven't. And by the end of the show, you'll have a greater understanding and appreciation of why I like it. In this episode, I chat with the co-founder & CEO of Feel More Labs, Francois Kress. It's a VC backed health and wellness technology company headquartered in New York. They are pioneering a new category of wearable devices that train and tune the nervous system. The company launched Cove, which is a wearable with a patented technology that applies gentle vibrations behind the ears that initiate a natural biological pathway between the skin and the brain to help people sleep better and improve resilience. Just to give a little more background into Francois, his previous positions include President of Louis Vuitton and Southeast Asia, the CEO of LVMH fashion group Oceania, the president of Fendi, North America, the CEO of Bulgari, Americas, the President, and CEO of product Americas, the global CEO of The Row, global president of Stuart Weitzman, and most recently global CEO of Carolina Herrera. He has also served as the board member of Kythera Biopharmaceuticals, which is a biotech company acquired by Allergan, he was educated in science at the prestigious Ecole Polytechnique in France and holds master's degrees in both international business and civil engineering, which you will understand why that connection is there between the fashion and luxury background as well as the deep interest in science and technology.  We'll talk about his background in the luxury goods market and the mindset behind the people who both run it and consume it. We'll talk about what Cove is and how it works and why they call it a hug for your mind. We'll talk about the science behind the specific biological pathway you've never heard of, that Cove works on which makes it really different. Of course, we're going to talk about some sleep hacks because this is The Best Night Ever. We'll also talk about the challenges of launching and growing a business during the pandemic. And if you are interested in learning more about this you can visit the website www.feelcove.com and use code: drjay20 for 20% off. 

Support the show