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Sylvia Asa is an endocrine pathologist leading University Hospitals in Cleveland, OH into the era of digital pathology. Previously, Dr. Asa was the Head of Pathology at Canada's largest hospital network, where she successfully built a digital pathology workflow. She joins Beyond The Scope to discuss the moment of realizing the power of digitizing a slide to achieving a fully integrated digital pathology workflow in Canada's largest medical network. As a Chair of the upcoming DPA Visions Conference (October 17-19 at the MGM Grand in Las Vegas), she previews the program and highlights some of the upcoming talks. Finally, Dr. Asa gives her thoughts on what the field of pathology may look like in 10-20 years.

A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

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Beyond the Scope returns as David and Giovanni discuss a publication from Archives of Pathology and Laboratory Medicine: "Digital Pathology Initiatives and Experience of a Large Academic Institution During the Coronavirus Disease 2019 (COVID-19) Pandemic". Topics include process to establish a 100% digital workflow, the remote validation process, and how the workflow was also useful for research and education. (24:49) Then, Harrison Dai (MS2, Eastern Virginia University) joins the show in a new segment sharing his experience as a medical student during the pandemic, in addition to the medical student perspective on digital pathology.

Reference paper:
https://meridian.allenpress.com/aplm/article/145/9/1051/464723/Digital-Pathology-Initiatives-and-Experience-of-a

DPA links:
https://digitalpathologyassociation.org/
https://dpa-dapa.com/login

A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

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Raj and Matt join Beyond the Scope to discuss the the Digital Anatomic Pathology Academy, hosted on PathPresenter - a primarily open source cloud based viewing platform for digital slides. DAPA is used as an educational, clinical, and publication tool. DPA members can access DAPA for free to make use of the numerous educational modules (dpa-dapa.com).

NOTE: this episode utilizes video for platform tutorials. Please visit https://digitalpathologyassociation.org/dpa-podcast-beyond-the-scope for the video version.

• 2:48 Guest intro
• 7:21 Introduction to the cloud based viewing and educational platform
• 8:47 Tutorial for navigating the platform
• 17:20 DAPA educational module features and demonstration
• 20:45 DAPA use cases; including an interactive way to study for boards
• 26:00 How DPA members and other can access the platform
• 27:50 Open source platform vs. licensed version for private data
• 30:10 MSKCC experience using the platform as an education portal and conference tool
• 33:00 Long term clinical goals of the platform
• 37:55 Utilizing the platform in underserved areas
• 39:23 Utilizing the platform for publications and E-books

A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

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Marilyn M. Bui, MD, PhD, FCAP is a senior member in the Department of Pathology at Moffitt Cancer Center where she serves as the scientific director of the Analytic Microscopy Core. She has previously served as president of the DPA and currently chairs many committees for CAP and DPA. Dr. Bui joins Beyond the Scope to discuss her work toward digital pathology adoption and building a connected network of pathologists.

• 1:58 Introduction and what it means to be a pathologist in the digital age
• 6:03 Evolution of pathology toward the digital era
• 10:18 How experience as a molecular biology researcher led to a career focused on DP/AI
• 14:25 Building relationships through the DPA and how to get involved
• 18:24 Highlights throughout the years of DPA leadership
• 22:34 Global digital pathology collaborations
• 24:23 DAPA - a cloud based platform for DP education
• 31:05 Using social media to promote DP adoption and education
• 32:47 Digital health initiatives at Moffitt Cancer Center
• 36:33 Current research projects in DP/AI
• 41:55 The future of pathology - how to improve the workforce,promote a healthy lifestyle, and decrease the workload

A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

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Chen Sagiv is an entrepreneur and computer scientist. She joins Beyond the Scope to discuss her story as a co-founder of DeePathology, a start-up providing AI tools for pathologists, as well as the challenges and excitement surrounding innovation in the digital pathology industry.

• 3:01 Introduction
• 7:29 Early applications of computer science in healthcare and why deep learning/AI methods are mandatory knowledge for modern computer scientists
• 11:15 The importance of cross disciplinary work between engineers, pathologists, and computer scientists
• 18:15 Story behind DeePathology and how the start-up helps pathologists use and understand AI tools
• 25:47 The perceived "black box" of AI vs. DIY AI platforms
• 31:50 Building AI algorithms from scratch
• 37:19 Advice for innovators in the pathology space

A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

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Dr. David Clunie is a radiologist, medical informaticist, DICOM open source software author and editor of the DICOM standard. He joins Beyond The Scope to discuss image format standards surrounding digital pathology adoption. For more information, please visit: https://www.dclunie.com/ .

• 3:00 Intro
• 4:15 Background on PACS and DICOM, and the importance to pathology
• 6:39 History of DICOM as the image standard for radiology
• 10:04 Why an image standard has yet to emerge for pathology
• 15:38 How pathology departments can work with IT departments to aid the digital transition
• 16:54 Clarifying misconceptions about PACS
• 21:52 Discussing all cost elements associated with digital pathology transition
• 27:43 Advice to pathologists regarding image archival standards long term
• 33:20 Collaborative efforts between pathology, radiology, and IT departments
• 37:22 Educating the pathology community on image standards and regulatory barriers
• 44:51 The role of enterprise IT in DP adoption

A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

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Raisa Glabman is a veterinary pathologist and a fellow in the NIH/NCI Comparative Biomedical Scientist Training Program (CBSTP). Raisa joins Beyond the Scope to discuss her research on immunotherapy and the tumor microenvironment, how researchers in her field are using DP/AI, and the current state of DP adoption in veterinary medicine.

• 2:28 Introduction
• 4:37 NCI CBSTP program
• 9:00 Why veterinary pathology is interested in DP/AI for clinical and research applications
• 12:45 What human and veterinary pathologists can learn from each other regarding DP adoption
• 16:30 DP applications in various veterinary pathology settings - industrial labs, academic centers, and small clinics
• 20:25 Raisa's research on immunotherapy and the tumor microenvironment
• 25:53 How Raisa is using DP/AI for her research
• 28:10 Doing research during the pandemic
• 29:43 Being an early adopter of DP/AI tools for this specific type of research
• 34:50 How DP will help researchers ask new scientific questions

A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

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George Green, Head of Pharmacodiagnostics at Bristol Meyers Squibb, joins Beyond the Scope to discuss the pharmaceutical industry's perspective on digital pathology and artificial intelligence. The conversation revolves around how digital pathology will see increased applications in the current era of precision medicine.

• 1:22 Introduction 
• 4:15 The companion diagnostics revolution in pharma
• 9:54 Early applications of digital pathology in pharma
• 14:38 How the mindset of pathologists has evolved since the dawn of DP/AI
• 19:55 Pharma perspective on how DP/AI will drive the future of precision medicine
• 25:00 Increasing DP adoption in the pharma industry
• 28:40 Digital pathology bringing better patient care around the world

A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

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Esther Abels, co-chair of the DPA Regulatory & Standards Task Force, has worked on the regulatory approval of digital pathology systems since the beginning. She joins Beyond The Scope to discuss her current role advancing the regulatory science of digital pathology and provides an update on the initiatives of the DPA Regulatory and Standards Task Force. Esther also discusses the excitement surrounding digital pathology for precision medicine.

• 2:21 Introduction
• 6:25 Early applications of digital pathology to the pharma industry
• 8:00 Process of validating and achieving FDA approval of the first slide scanners
• 10:00 How collaboration and teamwork help achieve regulatory approval
• 17:48 Current initiatives of the DPA Regulatory and Standars Task Force
• 21:40 510(k) exemption of digital pathology devices
• 25:00 Real world data initiative and is remote sign out permanent?
• 31:08 Using digital pathology for precision medicine

A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

Send us Fan Mail

Talat Zehra is a pathologist at Jinnah Sindh University in Karachi, Pakistan. Dr. Zehra joins Beyond The Scope to share how the scarcity of pathologists in Pakistan and many other regions of the world affect patient care. Dr. Zehra also discusses the advantages and challenges of bringing digital pathology to developing countries.

• 1:00 Introduction
• 3:30 Dr. Zehra's research with WSI in Pakistan
• 6:15 Pathology services in Pakistan and other developing countries
• 13:15 Pathology in rural areas of the world
• 14:33 Benefits of digital pathology in developing countries
• 17:42 Challenges of digital pathology adoption in developing countries
• 19:05 Ideas for vendors and other pathologists to help increase adoption in developing countries

Please visit other resources mentioned in this podcast:

https://digitalpathologyassociation.org/blog/digital-pathology-enabling-remote-operations-during-covid-19-pandemic-and-beyond-pathologist-perception-working-in-pakistan

https://healthcare-in-europe.com/en/news/digital-pathology-dawns-in-developing-countries.html

A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.