This week, we devote an entire hour to what one important scholar deemed “the cause of and solution to all of life’s problems.” From its earliest role as a source of nourishment to its depictions in ancient literature, we examine the roots of mankind’s everlasting drinking problems. Plus, how a bizarre 60 Minutes piece spread the idea that red wine has medicinal effects. Then, a look at how popular culture has incorrectly framed Alcoholics Anonymous as the best and only option for addiction recovery. And, a scientist cooks up a synthetic substitute for booze.

1. Iain Gately, author of Drink: A Cultural History of Alcohol, on the ancient origins of our core beliefs about booze. Listen.

2. Robert Taylor, assistant managing editor at Wine Spectator, on red wine's constantly changing reputation as a healthy substance. Listen.

3. Gabrielle Glaser [@GabrielleGlaser], author of Her Best-Kept Secret: Why Women Drink - And How They Can Regain Control, on the history and P.R. methods of Alcoholics Anonymous. Listen.

4. David Nutt [@ProfDavidNutt], psychologist at Imperial College London, on his new alcohol substitute, "alcosynth." Listen.

Songs:

When I Get Low I Get High by Ella Fitzgerald

Tomorrow Never Knows by Quartetto D/Archi Dell'Orchestra Sinfonica Di Milano

Il Casanova Di Federico Fellini by Solisti E Orchestre Del Cinema Italiano

Option with Variations by Kronos Quartet/composer Rhiannon Giddens