Last week, Health Secretary Robert F. Kennedy Jr. announced that the Food and Drug Administration would require all new vaccines to be tested against placebos and to develop new vaccines without using mRNA technology.

On Today's Show:
Christina Jewett, reporter covering Food and Drug Administration forThe New York Times, explains what that will mean for future drugs, including COVID-19 booster shots, plus more FDA-related news headlines.

With the impacts of President Trump's trade wars beginning to be felt in the US, we discuss the macro- and micro-economics of the administration's trade policy.

On Today's Show:
Kimberly Adams, senior Washington correspondent for Marketplace and the co-host of the Marketplace podcast “Make Me Smart,” talks about the latest news on tariffs, including the end of the de minimis exemption, which may lead to higher prices for consumers. Plus, Arthur Dong, professor of strategy and economics at the McDonough School of Business at Georgetown University, offers analysis of the US-China relationship as Beijing is considering whether it should begin to negotiate with President Trump on trade.

With officials and lawmakers in Washington D.C. discussing federal budget priorities, we look the coming year in government funding. 

On Today's Show:
Kadia Goba, politics reporter for Semafor, reports on the latest news from Congress, including where things stand on budget negotiations, the SAVE Act and more.

Several cases of the Trump administration's immigration detentions and deportations have raised questions about due process.

On Today's Show:
Nick Miroff, staff writer for The Atlantic who covers immigration and the Department of Homeland Security, talks about the behind the scenes negotiations between the Trump administration and the president of El Salvador about the US sending deportees there, regardless of their country of origin.
 

Defense Secretary Pete Hegseth had previously discussed  blocking women from military service, though has since backed off on those efforts.

On Today's Show:
Katherine Sharp Landdeck, professor of history and director of Pioneers Oral History Project at Texas Woman's University and the author of The Women with Silver Wings: The Inspiring True Story of the Women Airforce Service Pilots of World War II (Crown, 2020), talks about American women in the military over the last century.

After 100 days of Trump's second term, questions have arisen about birthright citizenship, the arrests of judges and deportations without due process.

On Today's Show:
David Remnick, editor of The New Yorker and the host of The New Yorker Radio Hour, offers his assessment of Trump's second term so far, and the opposition that is beginning to form.

Recently, NJ Sen. Andy Kim made an unannounced visit to a federal immigration detention facility. 

On Today's Show:
Andy Kim, U.S. Senator (D-NJ), talks about his work in the Senate and the issues facing the Garden State.

After his first few months in office, where have the initial actions of the Trump administration aligned with Project 2025?

On Today's Show:
David Graham, staff writer at The Atlantic, author of their daily newsletter, and author of The Project: How Project 2025 Is Reshaping America (Random House Trade Paperbacks, 2025), shares his analysis of President Trump's agenda.

The global influence of the Catholic church has been a historically important force on the international stage. 

On Today's Show:
Daniel Rober, associate professor and department chair of the Catholic Studies department at Sacred Heart University, talks about the leading contenders to be the next pope, the fraught process in the Vatican and the different directions the next leader of the world's Catholics might take the church.

What constitutes an "authoritarian" government, and what causes them to fail?

On Today's Show:
Anne Applebaum, staff writer at The Atlantic, historian and author of Autocracy Inc. (Penguin, 2024), argues the checks on presidential power, put in place by the founders, have so far failed in the second Trump administration.