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Part 1 of 3.
My guest for this weekâs episode is Bryan Dechairo, President, CEO, and Director at Sherlock Biosciences, an innovative biotech company that is enabling the democratization and decentralization of diagnostic testing to personalize healthcare and make an impact on global health. The Sherlock team and founders include engineering biology pioneers with world-leading expertise in CRISPR and synthetic biology, diagnostic industry veterans, and disease area authorities. Together, they provide an unparalleled set of capabilities that are transforming molecular diagnostics in clinical and non-clinical settings. Before Sherlock, and most recently, Bryan was Executive VP at Myriad Genetics and CSO and CMO at Assurex Health. His extensive career spans over two decades and also includes prominent positions at Medco Health, Pfizer, Oxagen, Sequana Therapeutics, and Roche. Bryan's vast experience working at both startups and Fortune 500 companies gives him unique insights that any entrepreneur can benefit from.
Join us as we sit down with Bryan as he discusses his early years growing up on a 10-acre hobby farm in Valley Center, Southern California, his decision to study integrative biology at UC Berkeley, and his early exposure to clinical diagnostics at Roche. Bryan talks about his transition to a startup, Sequana Therapeutics, and his love for that familial environment all while pursuing his PhD. Lastly, Bryan recounts embracing a new cultural experience in the UK while studying at the University College London. Please enjoy my conversation with Bryan Dechairo.
Find Our Guest, Bryan Dechairo, at these links:Â https://www.linkedin.com/in/bryandechairo/https://sherlock.bio/
Find Our Host, Jon Chee, at these links:Â https://www.linkedin.com/in/joncheehttps://www.excedr.com
Timestamps:
00:28 Intro
02:20 Episode starts, early days and upbringing, growing up in the 70s on a Southern California hobby farm
04:33 Being raised around science and research, finding business inspiration while being on a farm
08:02 Bryanâs decision to attend Berkeley and study Integrated Biology
11:00 Undergrad lab experience with genetics, mushroom hunting, volunteering for free experiences
15:23 Experiences and opportunities at Roche post-graduation, the opportunity to collaborate with competitors
19:19 Determining what was next after Roche, attended a life-changing career fair that led to working at Sequana Therapeutics
22:21 The enjoyment and family dynamic of working with a startup
26:23 A surprising and exciting move to the UK to work with Oxagen Ltd and receive a PhD at the University College of London
32:08 Outro
Social & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/
Enriched Notes:
Topics Mentioned:UC Berkeley https://en.wikipedia.org/wiki/University_of_California,_Berkeley What Is A PCR Machine? https://www.excedr.com/blog/what-is-a-pcr-machinePCR, qPCR, & DNA Amplification https://www.excedr.com/resources-category/pcr?47e8dc57_page=2What Is Polymerase Chain Reaction (PCR)? https://www.excedr.com/resources/what-is-polymerase-chain-reaction-pcrPCR Master Mix: Definition, Types, & More https://www.excedr.com/resources/pcr-master-mix-definition-types-and-moreHow PCR Systems Work & How We Save You Time & Money https://www.excedr.com/biotech-life-sciences/pcr-systemsGenetic Vectors: Overview, Types, & Applications https://www.excedr.com/resources/genetic-vectorsSingle-Cell Epigenomics: Changes to Genomes without DNA Alterations https://www.excedr.com/blog/single-cell-epigenomics
People Mentioned:Richard Brown https://www.legacy.com/us/obituaries/sandiegouniontribune/name/richard-brown-obituary?id=24374150Jamie Oliver https://en.wikipedia.org/wiki/Jamie_Oliver John Taylor https://www.linkedin.com/in/john-taylor-16953115/The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science companyâfrom pre-seed to IPO.
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