​In this episode, CSIS Senior Associate Jeffrey L. Sturchio speaks with Kathleen McManus, Assistant Professor of Medicine in the Division of Infectious Diseases and International Health at the University of Virginia Medical School, about what still needs to be done to achieve the ambitious goal of ending the HIV/AIDS epidemic in the United States. Professor McManus discusses how inequalities are driving HIV transmission and how they still affect vulnerable populations disproportionately, drawing on her experiences treating HIV patients in the Ryan White clinic at the University of Virginia. She also explores how the complicated and bewildering patchwork system of uneven coverage and access to HIV prevention and treatment services in the US healthcare system presents barriers to care and treatment for key populations at risk of HIV infection. The podcast concludes with Professor McManus’s reflections on what needs to be done at the state and local levels to translate the policy prescriptions of the US National HIV/AIDS strategy into service delivery programs that leave no one behind.