You’d be forgiven for being surprised if your doctor wrote you a prescription for ecstasy, ayahuasca, magic mushrooms, or LSD. But a recent resurgence in psychedelic research shows that a number of mental health conditions can be treated directly and effectively with potent psychoactive drugs. Dr. Dave Nichols has been studying the chemistry of these drugs for over 40 years, and he’s convinced of their therapeutic potential — and aware of the dangers of abuse. After a long psychedelic winter, are we ready to welcome these drugs back into the psychiatric fold?

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