To scale sustainably, founders must not neglect their mental health. Arianna Huffington learned this the hard way after collapsing from burnout while leading The Huffington Post. She talked with host Reid Hoffman about how that wake-up call sparked her next venture, Thrive Global, which helps companies build cultures that prioritize well-being. With work wellness insights from Huffington, Chris Yeh and Dr. Matt Walker, this 2018 episode feels more essential than ever.

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When Ju Rhyu moved to South Korea for a corporate job, she noticed people unapologetically wearing hydrocolloid pimple patches on their faces — on the street, at the office, anywhere. She soon realized no one had cornered the US market yet on this skincare secret, and Hero Cosmetics was born. Rhyu joins host Jeff Berman this week to reveal the lessons she learned as a first-time entrepreneur who built a brand that earned a $630 million exit.

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Bill Gates announced this week that he will shutter his philanthropic foundation in 20 years – but not before using it to give away $200 billion to fight global diseases. In this archival episode from 2019, he tells host Reid Hoffman the story of how it all started – and how he learned to scale his impact as a philanthropist.

In Part 2 of this special two-part conversation, we’re talking with Bill Gates about the biggest success story ever told on the podcast. It was achieved not through Microsoft, but through the Bill & Melinda Gates Foundation. Bill and Melinda have built their foundation into one of the world’s single largest private philanthropies, and they’ve done it by taking lessons learned at Microsoft – on how to massively capitalize on inflection points – and applied them to the nonprofit world. With some surprises along the way. Here's their story. 

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When Elon Musk stepped into the White House spotlight and brought his DOGE chainsaw, no one was better poised to cover the fallout than WIRED. The tech journalism outlet knew Musk’s playbook from the get-go, from years of covering his companies and his takeover of Twitter. WIRED’s Global Editorial Director Katie Drummond joins Rapid Response to take us inside Musk’s transformative, head-spinning time at President Trump’s side thus far. Drummond weighs the lasting impact of DOGE’s efforts 100 days in, and says that even as Musk announces plans to step back from politics, we can still expect plenty more to come.

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Dr. Iman Abuzeid didn’t set out to disrupt the healthcare hiring system. But after she began listening more closely — especially to nurses — what she heard was an industry full of friction, delays, and burnout. Fixing that friction became the foundation for Incredible Health, a hiring marketplace now used by more than a million healthcare workers. In this episode, Dr. Abuzeid talks with host Jeff Berman about her strategic approach to expansion and how scaling allows her to have more impact — and stay true to her calling.

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In his return to Rapid Response, the billionaire entrepreneur, NBA owner, and CEO of Wonder, Marc Lore, told us he plans all his meals with AI – and he loves it. It’s just one part of his vision for transforming our relationship to food and health. His startup Wonder has already acquired Blue Apron, Grubhub and the media brand Tastemade, and he shares how that’s all laddering up to a superapp for meal time. Plus, while many businesses are raising prices in the face of today’s volatility, Lore reveals why he’s taking the bold step to lower them.

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Spring cleaning season is in full swing, and this week, we’re revisiting Reid Hoffman’s chat with Adi Tatarko, co-founder and CEO of Houzz, an online platform for home remodeling and design. In this episode recorded in 2021, Tatarko tells the story of founding Houzz with her husband after their own home renovation project turned into a nightmare. They’ve grown Houzz into a bustling platform and marketplace for homeowners, designers, architects, and craftspeople. Tatarko’s story shows how following your frustration can lead to opportunities for scale.

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As the founder of World Central Kitchen, renowned chef and humanitarian José Andrés has truly mastered the art of leading through crisis. José returns to Rapid Response to share insights from his new book, Change the Recipe — a candid collection of personal stories that doubles as a playbook for navigating uncertainty, breaking rules, and leading with heart. José also explores how AI is poised to reshape the food industry, the importance of unplugging, and more. In a world seemingly on fire, José shows us how to harness that fire — without getting burned.

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As CEO and co-founder of Modern Animal, Steven Eidelman is challenging the status quo of veterinary care — an industry long overdue for innovation. In this episode, Eidelman unpacks how Modern Animal is rebuilding the system to better serve vets, pet owners, and their furry companions. With about 600 employees and a rapidly expanding footprint, it’s a scale story full of lessons for anyone who is tired of business as usual.

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Amid tariff whiplash and the rejuggling of global trade, GE Vernova’s CEO Scott Strazik is finding a way to stay “relentlessly optimistic.” Strazik returns to Rapid Response to share how the company plans to continue its success as one of Wall Street’s top-performing stocks, despite looming supply chain disruption, and an evolving conversation about climate and the energy transition. Strazik also reflects on rising trends in wind and nuclear energy, and why staying agile matters more than ever.

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