Masters of Scale

Few companies have as much influence over AI’s trajectory as OpenAI. Reid Hoffman sits down with CFO Sarah Friar to understand the precipice of the moment we are in and the decisions that could shape what comes next for each of us.

This conversation was recorded live as part of Masters of Scale Summit on October 21, 2026, at the Presidio Theatre in San Francisco.

Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribe

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

REI has been around for 88 years. Mary Beth Laughton wants to make sure it’s around for 88 more. The CEO of America’s largest consumer co-op joins Rapid Response to talk about what it actually takes to revive an iconic business — without shareholders, without quarterly earnings calls, and with 26 million members who hold you to a higher standard than any Wall Street analyst ever could. She explains why her first act as CEO was to publicly break ties with a Trump cabinet secretary, and how the co-op structure gives REI a kind of clarity that most retailers can’t buy. Plus lessons drawn from Nike, Sephora, and Athleta on what it really means to lead a mission-driven brand when the values are battle tested, not just stated.

Visit the Rapid Response website here: https://www.rapidresponseshow.com/

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Rich Roll’s popular podcast recently passed 1,000 episodes. He sat down with host Jeff Berman to discuss his growing podcast network, why he’s ignoring the algorithm, and his tumultuous path from addiction to wellness and endurance athletics. 

Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribe

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Renee Wegrzyn spent her career building the future of American science — including ARPA-H, the White House agency created to accelerate health breakthroughs. Then the Trump administration showed her the door. Wegrzyn co-founded Transfyr to tackle what she calls one of the most overlooked issues in science: the magic hands problem. She joins Rapid Response to explain why fixing this unglamorous bottleneck is the prerequisite for everything AI promises to deliver in medicine, what the federal funding cuts are really costing science, and why she can feel the next Sputnik moment coming — even if she can’t quite name it yet.

Visit the Rapid Response website here: https://www.rapidresponseshow.com/

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Thibault “Tibo” Sottiaux is OpenAI’s head of Product & Platform, making him responsible for the AI tools used by more than a billion users worldwide. Rana el Kaliouby spoke with Tibo on Pioneers of AI about why he’s “proud” OpenAI delayed its latest Astra model over safety concerns, the new suite of agentic products released at DevDay, and what it’s like to lead inside a frontier AI company in this extraordinary moment in history. 

Learn more about Pioneers of AI: http://pioneersof.ai/

Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Alyssa Ravasio loves using ‘coyote trickster energy’ to get more people to put down their technology. Her camping marketplace, Hipcamp, has grown into the largest source for booking campsites on public and private land. She talks with host Jeff Berman about scaling the company, learning to prioritize your health as a founder, and more. 

Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribe

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Prediction markets incentivize truth. Everything else incentivizes clickbait. That's the core argument Luana Lopes Lara makes for Kalshi — the prediction market platform she co-founded that has gone from $5 billion to $22 billion in valuation in under a year, and is now being sued by New York's attorney general for $36 billion. Luana joins Rapid Response to make the case that Kalshi is fundamentally different from DraftKings — even though 75% of its volume is sports — explain why George Santos got banned for trying to trade on his own congressional attendance, and share what Kalshi's data actually says about the midterms. Plus the Timothée Chalamet dentist-chair ad, what ballet taught her about running a company, and what it's actually like to become the world's youngest self-made female billionaire.

Visit the Rapid Response website here: https://www.rapidresponseshow.com/

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jennifer Ferro is the former board chair of NPR and president of Southern California’s iconic public radio organization: KCRW. Ferro talks with host Jeff Berman about how nearly two decades as the founder’s deputy taught her to lead, why she thinks we deserve a better internet, and how the best defense of getting ignored is simple: Don’t be boring.

Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribe

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The second a brand like Hershey stops being culturally relevant, says its CEO Kirk Tanner, you should be worried. He joins Rapid Response to explain exactly what he's doing to make sure that never happens. Tanner also reveals why GLP-1 users are actually good for the candy business, how AI is now routing Hershey's sales force in real time through Target and Walmart, and why the Reese's Oreo collaboration (which generated $100 million in its first five months) is the model for how iconic brands find new energy. And with a major Hollywood film about Milton Hershey coming this fall, he talks about whether this is Hershey's Barbie moment.

Visit the Rapid Response website here: https://www.rapidresponseshow.com/

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Own or be owned. That's Codie Sanchez's ultimatum for anyone serious about their financial future. The founder of Contrarian Thinking and author of the new book Own or Be Owned returns to Rapid Response to make her most impassioned case yet for why buying a small business is the most reliable path to wealth that most people are too scared to take. She breaks down what "cowboying" your business is costing you, and why AI isn’t a shortcut for everyone, but instead an accelerator for what's already inside you. Plus, the industries she'd invest in right now, and why most small business owners are solving the wrong problems.

Visit the Rapid Response website here: https://www.rapidresponseshow.com/

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.