CARTA - Anthropogeny (Audio)

Human beings show a range of emotional attachment, affection, and infatuation often referred to as “love”. Love promotes long-lasting and secure relationships that involve nurturing and support. Biological mechanisms underlying such behavior involve ancient neuropeptides and their receptors in the brain. These systems are also involved in reproduction, ranging from mating and pair-bonding, to giving birth and lactation. They shape the earliest experiences of all mammals and their mothers. The concept of love and how we experience it are affected by culture and its diverse societal norms. This symposium will explore the evolutionary roots of human love, compare human love to corresponding emotions in other animals, consider human conditions that prevent the expression of such feelings, and examine the key role of love and affection for our development and daily lives.  Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40506]

Human fathers exhibit hormonal shifts in testosterone, prolactin, and oxytocin, enabling flexible responses to parenting. In species with costly paternal care, these shifts balance mating and parenting efforts, suggesting evolved neuroendocrine capacities that support fatherhood. Today, fathers collaborate with mothers worldwide, though their roles vary across cultures and family systems, much as they likely did evolutionarily. Using research from the Philippines, Congo-Brazzaville, and the U.S., alongside cross-cultural data, this talk examines how men’s hormonal physiology adapts to parenthood and influences family behaviors and bonds within diverse ecological and cultural contexts. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40387]

The titi and owl monkeys of South America live in socially-monogamous groups where the male and female establish a pair bond and share parental duties. Why do males of these species mate in a monogamous relationship presumably foregoing other reproductive opportunities? And why are titi and owl monkey males such good fathers, investing heavily in the care of offspring that they cannot be certain they sired? Relying on ecological, behavioral and genetic data collected during 28 years from wild populations in Argentina, Peru and Ecuador. This lecture will discuss the role of food distribution, mate guarding and infant care in the evolution of pair-bonds, monogamy and paternal care. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40382]

Grandmothers play a key role as alloparents in human families. A leading hypothesis suggests that the inclusive fitness benefits of grandmaternal care selected for an extended female lifespan after reproduction, a unique trait among primates. Beyond lifespan extension, grandmothers may have biological adaptations for caregiving. Research from our lab shows grandmothers have lower DNA methylation of the oxytocin receptor gene (OXTR) compared to non-grandmothers, with lower methylation linked to stronger bonds with grandchildren. MRI scans reveal grandmothers have a lower brain age than controls, further reduced among those with higher engagement. These findings suggest grandmotherhood may enhance oxytocin signaling, promoting bonding and slowing brain aging. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40383]

Close relationships help us shape both our other social interactions as well as our internal physiology. Do these close relationships, also known as pair bonds, look and function similarly in species as diverse as titi monkeys, prairie voles, seahorses, and humans? How do negative experiences such as loss factor into, and perhaps strengthen, our close relationships? And what do we mean by luminance? This lecture will explore these topics while also touching on the underlying neurobiology of pair bonding. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40380]

Dr. Theofanopoulou studies neural circuits behind sensory-motor behaviors like speech and dance, aiming to develop drug- and arts-based therapies for brain disorders. Her brain imaging research reveals overlapping motor cortex regions controlling muscles for speech and dance, while transcriptomic studies show upregulation of the oxytocin gene pathway in key areas like the motor cortex and brainstem. Using zebra finches, Bengalese finches, white-rumped munias, and humans, she demonstrates oxytocin's role in vocal production. She also developed genomic tools to apply these findings across vertebrates. Her future work explores oxytocin-based drugs and dance therapies to treat speech and motor deficits in brain disorders. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40384]

Humans are an intensely social species. We experience social interactions as rewarding from infancy, and the social cognitive skills that we develop in the context of our earliest interpersonal attachments are critical for our survival and personal well being. Lack of social connection is common in many psychiatric and neurodevelopmental disorders. In some disorders, like autism spectrum disorder, social cognition and social interaction impairments are the defining, core feature. Yet, despite the importance of social functioning in humans, our understanding of the neurobiological mechanisms that regulate social behavior is limited. This lecture will describe the roles of two neuropeptides, oxytocin and vasopressin, in the regulation of social behavior in animals, and how findings from this research are providing fundamental insights into human social disorders, with a particular focus on vasopressin and autism spectrum disorder. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40381]

Oxytocin is a peptide molecule with a multitude of physiological and behavioral functions. Based on its association with reproduction, including social bonding, sexual behavior, birth and maternal behavior, oxytocin also has been called “the love hormone.” This presentation will examine parallels between the healing power of oxytocin and love. As described here, many myths and gaps in knowledge remain concerning oxytocin and love. A few of these are described and we hypothesize that the potential benefits of both love and oxytocin may be better understood in light of interactions with more ancient systems, including the autonomic nervous system, vasopressin and the immune system. The shared functions of oxytocin, love and sociostasis have profound implications for health and longevity, including the prevention and treatment of excess inflammation and related disorders, especially those occurring in early life and during periods of chronic threat or disease. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40379]

Human beings show a range of emotional attachment, affection, and infatuation often referred to as “love”. Love promotes long-lasting and secure relationships that involve nurturing and support. Biological mechanisms underlying such behavior involve ancient neuropeptides and their receptors in the brain. These systems are also involved in reproduction, ranging from mating and pair-bonding, to giving birth and lactation. They shape the earliest experiences of all mammals and their mothers. The concept of love and how we experience it are affected by culture and its diverse societal norms. This symposium will explore the evolutionary roots of human love, compare human love to corresponding emotions in other animals, consider human conditions that prevent the expression of such feelings, and examine the key role of love and affection for our development and daily lives.  Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40505]

Ancient texts warn of love turning into hatred, as seen in stories like Cain and Abel or “Et tu, Brute?” This talk explores the neurobiology of hatred based on the biology of love: the oxytocin system, attachment networks, and biobehavioral synchrony, which mature through mother-infant bonding and later support group solidarity and out-group hostility. Using this model, we developed Tools of Dialogue© for Israeli and Palestinian youth. After 8 sessions, participants showed reduced hostility, increased empathy, hormonal changes (lower cortisol, higher oxytocin), and lasting attitudes of compromise. Seven years later, these changes supported their peacebuilding efforts, showing how social synchrony can transform hatred into reciprocity and cooperation. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40386]