Autism just magically shows up.

"... I realized that all biochemistry is the bridesmaid to physics. I then realized that physics are how the business of cells gets completed. Light is the biophysical levers that control substrate level biochemistry in cells." - Dr. Jack Kruse

(Start here) Regenerative Health with Dr. Max Gulhane and Dr. Jack Kruse https://www.youtube.com/watch?v=Ln3WszTq0uA

Decentralized is the way (The Status Quo is NO GOOD) https://www.youtube.com/watch?v=VO4JwdXuXXs

Tryptophan Biosynthesis https://faseb.onlinelibrary.wiley.com/doi/epdf/10.1096/fj.04-2079rev

Autism and Melanin https://www.patreon.com/posts/quantum-45-83724567

0:00 Introduction & Framing Podcast blends science, personal experience, and opinion to explain autism. Autism “appeared” around 1938 (Kanner/Asperger), with rates rising sharply. Parallels to post-1880s conditions (Alzheimer’s 1906, diabetes, obesity, ADHD) linked to electrification.

5:30 Central Thesis: Light as the Common Environmental Factor Light is the key environmental change. Pre-1880s: sunlight/fire (red/IR-rich). Modern: blue-heavy artificial light. Disrupts vitamin A/B/D, amino acids, water, melanin, melanopsin, POMC.

12:00 Cellular & Mitochondrial Mechanisms Blue light dehydrates cells, disrupts TCA cycle and ATP production. Mitochondria need red/NIR for oxygen-to-water conversion; blue causes hypoxia/stress. Universal cellular vulnerability explains issues without added toxins.

19:00 Neuroplasticity & Autism as Adaptation Autism as extreme neuroplasticity adapting to light stress, like blind individuals repurposing visual cortex.

22:00 Lifespan Symmetry: Autism Dementia Autism and dementia rates mirror across lifespan. Both show early retinal damage. Artificial light at night exploded post-1940s, enabling 24/7 life at biological cost.

26:00 Light Spectra Compared Sun: 250–3100 nm, 43–47% red/IR. Incandescent/fire: warm/red-dominant. LEDs: blue peak (460–480 nm). Indoor dim vs. outdoor bright. Vitamin D inverse with autism; lower rates near equator.

31:00 Wavelength-Specific Benefits

37:00 The Unsung Hero Melanin absorbs all light to power biology and protect vs. stress/toxins. Neuromelanin links to Parkinson’s; autism raises Parkinson’s risk 3x.

48:00 Tryptophan → Serotonin → Melatonin Pipeline UVB activates tryptophan → serotonin → melatonin (95% mitochondrial). Blue light causes radicals, disrupts cells. Serotonin modulates development, sensory, gut

58:00 Rapid brain growth needs optimal light. Autism disrupts cell migration, speech/motor/sensory. GABA switch vulnerable.

1:07:00 B-Vitamins & UVB-dependent; blue disrupts folate/B12 for DNA methylation.

1:14:00 Autism rise coincides with electrification. More sunlight in pregnancy could reduce risk

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